Reversed-Phase Point-of-use Purifier for the Removal of Trace Organics in High Purity Water Recent developments of Liquid Chromatography instrumentation, such as UHPLC coupled with mass spectrometry, have increased the separation efficiency and sensitivity. Unfortunately, there are some
unwelcome consequences. One of these is the detection of trace contamination in the solvents used to prepare mobile phases. The aim of this work was to design a cartridge which produces high water quality for very sensitive LC-MS applications.