Corporate Banner
Satellite Banner
Mass Spectrometry
Scientific Community
Become a Member | Sign in
Home>Resources>Application Notes>This Application Note
  Application Notes
Scientific News
New Hope for Personalized Treatment of Eczema
Pharmaceutical researchers at Oregon State University have developed a new approach to treat eczema and other inflammatory skin disorders that would use individual tests and advanced science to create personalized treatments based on each person's lipid deficiencies.
Flowing Electrons Help Ocean Microbes Gulp Methane
Recent work at Caltech has shown that microbes work together to consume large amounts of methane released from vents on the ocean floor by using electrons to share energy over long distances.
Thousands of Protein Interactions Identified
Thanks to the work by Utrecht University researcher Fan Liu and her colleagues, it is now possible to map the interactions between proteins in human cells.
Newly Identified Biochemical Pathway Could Be Target for Insulin Control
Researchers at Duke Medicine and the University of Alberta are reporting the identification of a new biochemical pathway to control insulin secretion from islet beta cells in the pancreas, establishing a potential target for insulin control.
Dirty,Crusty Meals Fit for (Long-Dormant) Microbes
Researchers apply the latest analytical techniques to further our understanding of desert biocrusts.
CSI -- On The Metabolite's Trail
Bioinformaticians at the University of Jena make the most efficient search engine for molecular structures available online.
First Complete Structural Study Of A Pegylated Protein
Significant data obtained at NUI Galway reports first crystal structure of a protein modified with a single PEG chain.
Potential Ovarian Cancer Biomarker Isolated
Researchers from North Carolina State University utilized a highly sensitive mass spectrometry analysis to identify and measure difficult-to-detect N-glycan biomarkers associated with ovarian cancers in stages I – IV.
Waters’ Centers of Innovation Program Honors Ohio State University Laboratory
Wysocki-led facility recognized for proteomics, disease research and mass spectrometry excellence.
Protein Aggregation After Heat Shock Is An Organized, Reversible Response
New study finds protein aggregation after heat exposure is a reversible cellular process, not unrecoverable damage from misfolding.
Scroll Up
Scroll Down

Simple sample preparation for the determination of vitamin D in serum by LC-MSMS
Bookmark and Share

Tecan Group Ltd.

Prior to any analysis by LC-MSMS, a sample clean-up step is recommended in order to remove matrix components such as proteins, lipids, carbohydrates and salts. 

The current methods for sample preparation require at least one labor-intensive and time-consuming step, such as filtration, centrifugation or solvent evaporation. In addition, these steps prevent straightforward automation of the sample preparation process, which is highly desirable in order to cope with the increasing number of vitamin D determinations and sample load experienced by many laboratories. 

The AC Extraction Plate simplifies sample preparation by eliminating the need for centrifugation, filtration or solvent evaporation steps. 

This application note demonstrates the suitability of the AC Extraction Plate for sample preparation prior to the determination of vitamin D in serum by LC-MSMS, along with details of the workflow and how to use the AC Extraction Plate. 

Further Information

Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,600+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,800+ scientific videos