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Mass Spec Technology Drives Innovation Across the Biopharma Workflow
With greater resolving power, analytical speed, and accuracy, new mass spectrometry technology and techniques are infiltrating the biopharmaceuticals workflow.
Gene Deletion Reveals Cell Secrets
Researchers have deleted 174 genes in yeast to analyse the effect of individual gene deletion.
Peer Reviewed Study Demonstrates Mass Spec Technique
The peer reviewed study demonstrates MS workflow, TMTCalibrator workflow, which dramatically enhances detection of key early stage Alzheimer’s biomarkers.
Impact of Emerging Contaminants in Our Water Supply
Emerging contaminants, any synthetic or naturally occurring chemical not commonly monitored in the environment, in our water supply are becoming of increasing concern due to their potential ecological and/or human health effects.
Collaboration to Develop Cannabis Testing Standards
SCIEX workflow solution enables cannabis labs to ensure product safety with robust, cost-effective analytical methods to facilitate routine testing.
Antibiotic Resistance Genes in Indoor Dust
Genetic analyisis of dust samples discovered antimicrobial chemicals and antibiotic-resistance genes.
Sharks Contain High Levels of Neurotoxins Linked to Alzheimer’s
Research team suggests restricting shark consumption to protect human health as shark fins & meat contain high levels of neurotoxins.
Peptide Mutants Help Identify Vulnerability in Tumor Cells
Researchers can detect mutant proteins based on MS data and the results of exome sequencing.
Diverse Fungi Secrete Similar Suite of Decomposition Enzymes
A recent study reveals different fungal species secrete a rich set of enzymes that share similar functions, despite species-specific differences in the amino acid sequences of these enzymes.
Misfiring Drugs Hit the Wrong Targets
Anti-HIV protein inhibitor drugs can bind to the wrong protein, causing unwanted side effects.
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Unified Laboratory Intelligence for Impurity Resolution Management
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ACD Labs

Maximizing the effective patent life of a marketed drug is one of the main priorities for researchers. According to a March 2010 article in Nature, the estimated average cost for pharmaceutical companies to bring a new chemical entity (NCE) to market is approximately 1.8 billion and requires 13.5 years on average. Identifying and characterizing an impurity in a couple of days less time can literally equate to a gain of a million dollars in net present value. Being able to do this repeatedly as impurities are encountered through the drug development and acceptance of a drug substance can shave weeks, or even months, off the time to market, increasing returns by millions of dollars.

Unified Laboratory Intelligence (ULI) is a category of R&D informatics that combines software, algorithmic tools, and databases to form a scalable platform for the collection and unification of chemical, structural, and analytical data. ULI accumulates information and knowledge from successive projects across different chemistry disciplines to create a one-to-many chemical intelligence-from-information ‘live’ cycle. With ULI, scientists can easily search and quickly retrieve ‘live’ data to gain and apply intelligence and insight that improves decision-making. 

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RTI Launches New Spectral Database for Forensic Laboratories, Research and Law Enforcement
RTI International, funded by a grant from the National Institute of Justice (NIJ), has created 'Forensic DB', a cheminformatics database for the retention, review, and ongoing collection of spectroscopic data pertaining to toxins, drugs, and other compounds of interest to the forensics community.
Wednesday, December 08, 2010
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