Thursday, May 17, 2012
Technology Networks
Technology Networks
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 | The Potassium Channels Kv1.3 and KCa3.1 as Targets for Inflammatory Brain Pathologies Professor Heike Wulff, University of California, speaking at Ion Channel Targets 2011. |
 | Alpha2* Nicotinic Acetylcholine Receptors as a Therapeutic Target for Memory Enhancement Dr Katumi Sumikawa, University of California, speaking at Ion Channel Targets 2011. |
Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists - A Target Pipeline and Stakeholder Analysis 2012
La Merie
This report provides a compilation of business, commercial, clinical and scientific information about GLP-1 receptor agonists. A comprehensive analysis of the state of the art and key trends guides the reader through this emerging antidiabetic drug class. Scientific and technological approaches as well as molecules in the target pipeline of GLP-1 receptor agonists are described and assessed.
Life Science and Chemical Instrumentation Market (2011 - 2016)
MarketsandMarkets
Spectroscopy, Chromatography, DNA Sequencer & Amplifier, Lab Automation, Array, Flow Cytometer, Electrophoresis, Immuno Assay & Others
Multi-Mode Microplate Reader Trends
HTStec
This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on multi-mode microplate readers carried out in September 2011.
Emerging Pharmaceutical Markets 2012
Select Biosciences Ltd
The report covers all the key aspects of the various emerging pharmaceutical markets and has broadly outlined the factors that are affecting the industry. The report also provides current and predicted future performance of the pharmaceutical market in different regions of the world.
The Future of GPCRs in Drug Discovery
Business Insights
This report analyzes which classes of GPCR and specific GPCRs have been exploited. It looks at novel approaches to targeting GPCRs and their benefits and explores potential targets that could be of relevance to major, under-treated diseases. The report profiles small companies specializing in specific aspects of GPCR technology and analyzes the commercial outlook drugs targeting GPCRs.
Top 10 Drug Discovery Technologies - Strategic Analysis and Global Forecasts
MarketsandMarkets
The top 10 drug discovery technologies play a vital role in the growth of the entire pharmaceutical industry as they are the key contributors in the swift introduction of blockbusters and innovative drugs. The applications of these technologies in the introduction of drugs have created significant opportunities for market growth. The slow introduction of new blockbuster drugs is a major concern which the drug development companies are catering to by using these top technologies.
La Merie
This report provides a compilation of business, commercial, clinical and scientific information about GLP-1 receptor agonists. A comprehensive analysis of the state of the art and key trends guides the reader through this emerging antidiabetic drug class. Scientific and technological approaches as well as molecules in the target pipeline of GLP-1 receptor agonists are described and assessed.
Life Science and Chemical Instrumentation Market (2011 - 2016)
MarketsandMarkets
Spectroscopy, Chromatography, DNA Sequencer & Amplifier, Lab Automation, Array, Flow Cytometer, Electrophoresis, Immuno Assay & Others
Multi-Mode Microplate Reader Trends
HTStec
This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on multi-mode microplate readers carried out in September 2011.
Emerging Pharmaceutical Markets 2012
Select Biosciences Ltd
The report covers all the key aspects of the various emerging pharmaceutical markets and has broadly outlined the factors that are affecting the industry. The report also provides current and predicted future performance of the pharmaceutical market in different regions of the world.
The Future of GPCRs in Drug Discovery
Business Insights
This report analyzes which classes of GPCR and specific GPCRs have been exploited. It looks at novel approaches to targeting GPCRs and their benefits and explores potential targets that could be of relevance to major, under-treated diseases. The report profiles small companies specializing in specific aspects of GPCR technology and analyzes the commercial outlook drugs targeting GPCRs.
Top 10 Drug Discovery Technologies - Strategic Analysis and Global Forecasts
MarketsandMarkets
The top 10 drug discovery technologies play a vital role in the growth of the entire pharmaceutical industry as they are the key contributors in the swift introduction of blockbusters and innovative drugs. The applications of these technologies in the introduction of drugs have created significant opportunities for market growth. The slow introduction of new blockbuster drugs is a major concern which the drug development companies are catering to by using these top technologies.
Fall in Deaths Following Withdrawal of Pain Killer
Reduction in deaths after withdrawn of pain-relief drug co-proxamol in UK.
Interfacing Medicinal Chemistry with Structural Bioinformatics
The observed aaRS-specific stability differences between key riboswitch structural elements could potentially be targeted to effect ligand-specificity in future drug discovery efforts.
Revolutionary New Cancer Targeting Technology Described in Nature Medicine
Immunocore scientists manage to overcome cancer problem by boosting the ability of cancer-specific TCRs.
Anti-HIV Drug Use During Pregnancy Does Not Affect Infant Size, Birth Weight
NIH study indicates drug safe during pregnancy, but infants smaller at first birthday.
Prosonix Demonstrates Improved Delivery and Co-localization of Respiratory Medicines
New review published in European Respiratory Disease(ERD).
Design, Synthesis and Activity Study of Aminopeptidase N Targeted AHPA Derivatives
APN was shown to be involved in the degradation of extracellular matrix in tumor invasion and may serve as a target receptor for drug delivery into tumors and also contribute to angiogenesis.
Researchers Turn Big Data Problems into Advanced Biology and Drug Discoveries
University of Illinois at Chicago and The Genome Analysis Centre in Norwich, UK leverage SGI(R) UV(TM) to accelerate drug discovery and complex problem analysis.
New Research on Zebrafish Brings a Cure for Hearing Loss Closer
Zebrafish to discover drugs that may lead to the restoration of hearing.
Enabling Large-Scale Design, Synthesis and Validation of Small Molecule Protein-Protein Antagonists
With the number of new drug applications (NDA) on the decline, a new approach that stops our dependence from old compounds, and utilizes the vast information available on protein interactions and structure, is desperately needed.
Preclinical Predictors of Anticancer Drug Efficacy: Critical Assessment with Emphasis on Nanomolar Potency
This article looks at prediction of cancer drug efficacy in its ultimate user, the human patient and reviews current knowledge followed by illustrative examples that, in the absence of definitive data, provide an empirical perspective.
Reduction in deaths after withdrawn of pain-relief drug co-proxamol in UK.
Interfacing Medicinal Chemistry with Structural Bioinformatics
The observed aaRS-specific stability differences between key riboswitch structural elements could potentially be targeted to effect ligand-specificity in future drug discovery efforts.
Revolutionary New Cancer Targeting Technology Described in Nature Medicine
Immunocore scientists manage to overcome cancer problem by boosting the ability of cancer-specific TCRs.
Anti-HIV Drug Use During Pregnancy Does Not Affect Infant Size, Birth Weight
NIH study indicates drug safe during pregnancy, but infants smaller at first birthday.
Prosonix Demonstrates Improved Delivery and Co-localization of Respiratory Medicines
New review published in European Respiratory Disease(ERD).
Design, Synthesis and Activity Study of Aminopeptidase N Targeted AHPA Derivatives
APN was shown to be involved in the degradation of extracellular matrix in tumor invasion and may serve as a target receptor for drug delivery into tumors and also contribute to angiogenesis.
Researchers Turn Big Data Problems into Advanced Biology and Drug Discoveries
University of Illinois at Chicago and The Genome Analysis Centre in Norwich, UK leverage SGI(R) UV(TM) to accelerate drug discovery and complex problem analysis.
New Research on Zebrafish Brings a Cure for Hearing Loss Closer
Zebrafish to discover drugs that may lead to the restoration of hearing.
Enabling Large-Scale Design, Synthesis and Validation of Small Molecule Protein-Protein Antagonists
With the number of new drug applications (NDA) on the decline, a new approach that stops our dependence from old compounds, and utilizes the vast information available on protein interactions and structure, is desperately needed.
Preclinical Predictors of Anticancer Drug Efficacy: Critical Assessment with Emphasis on Nanomolar Potency
This article looks at prediction of cancer drug efficacy in its ultimate user, the human patient and reviews current knowledge followed by illustrative examples that, in the absence of definitive data, provide an empirical perspective.
GSK to Fully Acquire Cellzome for £61 Million
GSK to further expand its platform technology expertise with acquisition of chemical proteomics company.
YM BioSciences Reports Operational and Financial Results for the Third Quarter of Fiscal 2012
Pivotal trials for CYT387 in myelofibrosis to begin in the second half of calendar 2012.
Antisense Pharma Internationalizes Management Board
Dr. Philippe Calais appointed Chief Executive Officer.
Prosonix to Present at RDD 2012 and ATS 2012 International Conference
Prosonix will present a poster entitled ‘Engineered Combination Respiratory Medicines for Localized Drug Delivery’ at RDD.
Pliaglis Receives Positive Opinion from the BfArM in the E.U.
Enters national licensing phase in 17 E.U. countries.
Verona Pharma Appoints New CEO
Appointment of experienced biotechnology CEO as part of succession planning.
Horizon and H3 Biomedicine to Collaborate
H3 Biomedicine to employ Horizon’s unique gene editing technology and isogenic cell lines to validate genetically defined drug targets for development of cancer therapeutics.
Nuvo Research Announces 2012 First Quarter Results
U.S. prescriptions of Pennsaid continued to grow quarter-over-quarter.
Creabilis Appoints Dr Simon Russell as Chief Business Officer
Dr Russell to maximize the commercial potential of Company’s products and technology.
ELRIG Announces Speaker Programme for Drug Discovery 2012 Conference
The 6th Annual Drug Discovery Conference, in collaboration with SLAS, will be held at Manchester Central Convention Complex on 5th – 6th September 2012.
GSK to further expand its platform technology expertise with acquisition of chemical proteomics company.
YM BioSciences Reports Operational and Financial Results for the Third Quarter of Fiscal 2012
Pivotal trials for CYT387 in myelofibrosis to begin in the second half of calendar 2012.
Antisense Pharma Internationalizes Management Board
Dr. Philippe Calais appointed Chief Executive Officer.
Prosonix to Present at RDD 2012 and ATS 2012 International Conference
Prosonix will present a poster entitled ‘Engineered Combination Respiratory Medicines for Localized Drug Delivery’ at RDD.
Pliaglis Receives Positive Opinion from the BfArM in the E.U.
Enters national licensing phase in 17 E.U. countries.
Verona Pharma Appoints New CEO
Appointment of experienced biotechnology CEO as part of succession planning.
Horizon and H3 Biomedicine to Collaborate
H3 Biomedicine to employ Horizon’s unique gene editing technology and isogenic cell lines to validate genetically defined drug targets for development of cancer therapeutics.
Nuvo Research Announces 2012 First Quarter Results
U.S. prescriptions of Pennsaid continued to grow quarter-over-quarter.
Creabilis Appoints Dr Simon Russell as Chief Business Officer
Dr Russell to maximize the commercial potential of Company’s products and technology.
ELRIG Announces Speaker Programme for Drug Discovery 2012 Conference
The 6th Annual Drug Discovery Conference, in collaboration with SLAS, will be held at Manchester Central Convention Complex on 5th – 6th September 2012.
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Analyzing Molecular Polar Surface Descriptors to Predict Blood-Brain Barrier Permeation
University of Würzburg
Permeation of active drugs across the vascular brain endothelium into the central nervous system (CNS) is controlled by the blood-brain barrier (BBB). Some molecular quantities like polar surface (PS) descriptors are of key interest to medicinal chemists to predict the BBB permeation fate for different drug-like chemical compounds.
Classification of Drugs by CNS Access: An Insight from Quantitative Blood-Brain Transport Characteristics
Advanced Chemistry Development
Aim of this study was to identify relationships between quantitative blood-brain transport parameters and qualitative data indicating whether the compound penetrates into the brain efficiently enough to exhibit action in the CNS.
An In Silico Test Battery for Rapid Evaluation of Genotoxic and Carcinogenic Potential of Chemicals
Advanced Chemistry Development Inc
The FDA guidance for industry states impurities under the ICH threshold may be exaluated for genotoxicity and carcinogenicity. This study uses an expert system to detect mutagens and compounds labeled as potent carcinogens by the FDA.
UPLC-MS/MS for the Screening, Confirmation and Quantification of 32 Drugs Illegally Added to Herbal/Dietary Supplements for the Enhancement of Male Sexual Performance
Supreme Council of Health, Qatar
This poster outlines development of a novel screening method that is suitable for both the detection of known and unknown ED drugs and analogues. Comprehensive spectral data is collected and automatically compared to a prepared library if known drugs.
A Simple, Robust Automated Multiplexed Cell-Based Assay Process for the Assessment of Mitochondrial Dysfunction and Cytotoxicity
Biotek Instruments
Recent studies have shown that an increasing number of drugs no longer on the market have negative effects on mitochondrial function in key organs such as the liver and heart. Therefore it is increasingly important to monitor the effects of lead compounds on mitochondrial function in relevant cell systems. The ability to incorporate a simple, rapid, multiplexed, predictive assay can make the detection of potential toxic effects easier to perform early on in the drug discovery process.
An Automated, Cell-based Platform for the Rapid Detection of Novel Androgen Receptor Modulators
BioTek Instruments
The Androgen Receptor (AR) is a member of the family of nuclear receptors responsive to steroid hormones. This poster aims to devise, validate and perform a preliminary automated HTS screening campaign to identify novel modulators of AR activity.
Validation of an Automated Cell-Based Bioluminescent TNFa Blocker Bioassay
BioTek Instruments
TNFa blocker biopharmaceuticals represent an important and successful class of protein drugs used in the treatment of several autoimmune diseases. Bioassays are indispensible tools in biopharmaceutical drug development and commercialization that are used to quantify biological activity and stability of drugs or drug candidates. The automation of these assays can serve to create an accurate, robust process which can allow the researcher to perform other more important functions.
Automation of a Generic Fluorescence Methyltransferase Activity Assay
BioTek Instruments
Epigenetic processes are attracting considerable attention in drug discovery as their fundamental roles in controlling normal cell development and contributions to disease states become more clearly defined. This work combines a fluorescence-based assay with liquid handling and dispensing instrumentation and a multi-mode reader which can be used to monitor the biological activity of the histone methyltransferase (HMT) G9a, a model system.
Modeling Disposition of Sotalol following Intravenous and Oral Administration in Healthy Adult Subjects
Simulations Plus
Sotalol is a non specific adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmia. Its absorption, distribution and systemic PK or, collectively, ‘disposition’ was modeled and simulated using GastroPlus™ v7.0. Biopharmaceutical properties were obtained from in silico predictions and in vitro measurements.
Predicting hERG Potassium Channel Affinity with Artificial Neural Network Ensembles
Simulations Plus
Modeling hERG inhibition has gained significant popularity since 2005, when the FDA recognized the correlation between hERG inhibition and a prolonged QT interval by issuing guidance for the evaluation of new non-antiarrythmic drugs against the hERG channel.Long QT syndrome or LQTS is a risk factor for ventricular tachyarrhythmias and sudden death.
University of Würzburg
Permeation of active drugs across the vascular brain endothelium into the central nervous system (CNS) is controlled by the blood-brain barrier (BBB). Some molecular quantities like polar surface (PS) descriptors are of key interest to medicinal chemists to predict the BBB permeation fate for different drug-like chemical compounds.
Classification of Drugs by CNS Access: An Insight from Quantitative Blood-Brain Transport Characteristics
Advanced Chemistry Development
Aim of this study was to identify relationships between quantitative blood-brain transport parameters and qualitative data indicating whether the compound penetrates into the brain efficiently enough to exhibit action in the CNS.
An In Silico Test Battery for Rapid Evaluation of Genotoxic and Carcinogenic Potential of Chemicals
Advanced Chemistry Development Inc
The FDA guidance for industry states impurities under the ICH threshold may be exaluated for genotoxicity and carcinogenicity. This study uses an expert system to detect mutagens and compounds labeled as potent carcinogens by the FDA.
UPLC-MS/MS for the Screening, Confirmation and Quantification of 32 Drugs Illegally Added to Herbal/Dietary Supplements for the Enhancement of Male Sexual Performance
Supreme Council of Health, Qatar
This poster outlines development of a novel screening method that is suitable for both the detection of known and unknown ED drugs and analogues. Comprehensive spectral data is collected and automatically compared to a prepared library if known drugs.
A Simple, Robust Automated Multiplexed Cell-Based Assay Process for the Assessment of Mitochondrial Dysfunction and Cytotoxicity
Biotek Instruments
Recent studies have shown that an increasing number of drugs no longer on the market have negative effects on mitochondrial function in key organs such as the liver and heart. Therefore it is increasingly important to monitor the effects of lead compounds on mitochondrial function in relevant cell systems. The ability to incorporate a simple, rapid, multiplexed, predictive assay can make the detection of potential toxic effects easier to perform early on in the drug discovery process.
An Automated, Cell-based Platform for the Rapid Detection of Novel Androgen Receptor Modulators
BioTek Instruments
The Androgen Receptor (AR) is a member of the family of nuclear receptors responsive to steroid hormones. This poster aims to devise, validate and perform a preliminary automated HTS screening campaign to identify novel modulators of AR activity.
Validation of an Automated Cell-Based Bioluminescent TNFa Blocker Bioassay
BioTek Instruments
TNFa blocker biopharmaceuticals represent an important and successful class of protein drugs used in the treatment of several autoimmune diseases. Bioassays are indispensible tools in biopharmaceutical drug development and commercialization that are used to quantify biological activity and stability of drugs or drug candidates. The automation of these assays can serve to create an accurate, robust process which can allow the researcher to perform other more important functions.
Automation of a Generic Fluorescence Methyltransferase Activity Assay
BioTek Instruments
Epigenetic processes are attracting considerable attention in drug discovery as their fundamental roles in controlling normal cell development and contributions to disease states become more clearly defined. This work combines a fluorescence-based assay with liquid handling and dispensing instrumentation and a multi-mode reader which can be used to monitor the biological activity of the histone methyltransferase (HMT) G9a, a model system.
Modeling Disposition of Sotalol following Intravenous and Oral Administration in Healthy Adult Subjects
Simulations Plus
Sotalol is a non specific adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmia. Its absorption, distribution and systemic PK or, collectively, ‘disposition’ was modeled and simulated using GastroPlus™ v7.0. Biopharmaceutical properties were obtained from in silico predictions and in vitro measurements.
Predicting hERG Potassium Channel Affinity with Artificial Neural Network Ensembles
Simulations Plus
Modeling hERG inhibition has gained significant popularity since 2005, when the FDA recognized the correlation between hERG inhibition and a prolonged QT interval by issuing guidance for the evaluation of new non-antiarrythmic drugs against the hERG channel.Long QT syndrome or LQTS is a risk factor for ventricular tachyarrhythmias and sudden death.
Measurement of Phenolic Compounds in Red Wines Using the SpectraMax® Plus384 Microplate Reader
Molecular Devices
Measurement of tannin, iron-reactive phenolics, anthocyanin and polymeric pigment in red wine is an important part of quality control in the wine industry. Precise and reliable measurement of phenolic compounds in wine is critical for making decisions during fermentation, maceration, pressing and blending. Harbertson et al. developed a comprehensive red wine phenolics assay in 2003.1 Traditionally this assay is performed using a cuvette-based UV-vis spectrophotometer. It is a time-consuming and
Cytotoxicity in Cells: Easy Determination Using Lonza ViaLight Plus and ToxiLight BioAssays on the SpectraMax L Microplate Luminometer
Molecular Devices
Bioluminescent cytotoxicity assays offer the user increased detection limits, speed, and accuracy, and have been well documented (Crouch et al., 1993). Healthy cells maintain a high constant ATP concentration in culture. During proliferation, the total ATP in the culture increases in line with cell number. Conversely, dying cells are unable to maintain their high ATP level, as synthesis becomes compromised, and so levels are seen to reduce. The level of ATP present within a culture is indicative
Microplate-Based Endotoxin Testing in GLP/GMP Environments with the VersaMax™ Absorbance Microplate Reader and Pyrochrome® Assay
Molecular Devices
Monitoring for contaminants is a critical step during the production process in the pharmaceutical and medical device industries. A frequent contaminant, endotoxin, can cause fever, inflammation, headache, nausea, and even death. Found in the cell wall of gram negative bacteria, endotoxin has routinely been detected by the sensitive and specific Limulus Amebocyte Lysate (LAL) assay. In the presence of endotoxins, LAL coagulates through an enzyme-mediated cascade, which has then been traditional
Heating on an Atlas Hotplate
Syrris Ltd
In the following experiments, different vessels were heated using the Atlas hotplate, with and without the Atlas Stacking Drybath. In every case, an external thermocouple probe has been used with the system to accurately measure “reaction” temperature.
Analysing Endotherms using Atlas
Syrris Ltd
This application note shows how atlas and reaction monitoring can be used to look at endothermic processes.
Tracking Exotherms using Atlas Reaction Monitoring
Syrris Ltd
This application note shows how atlas and reaction monitoring can be used to look at exothermic processes.
Reaction Monitoring with Atlas 1
Syrris Ltd
This application note reports the use of the atlas system to monitor the hydrolysis of acetic anhydride, a typical test reaction for exothermic processes.
Reaction Monitoring with Atlas 2
Syrris Ltd
This application note details an experiment to show the repeatability and scalability of reaction monitoring signals by using an electrical heater system.
Examples of FRX Applications for Demonstration
Syrris Ltd
FRX as a product offers a wide range of applications in a number of areas. To try and increase the exposure of the product to a wider audience, two standard demonstrations are detailed here. The first is a Wittig reaction showing the operation of an FRX200 system. The second is a separation of water and ethyl acetate demonstrating the operation of the FLLEX (Flow Liquid Liquid EXtraction module), for FRX300 or FRX400.
Cleaning Microreactors
Syrris Ltd
This application note gives hints and tips on cleaning & unblocking flow reactors, i.e. chips or tube based reactors. It is suggested that the whole document is read before attempting to unblock a reactor.
Molecular Devices
Measurement of tannin, iron-reactive phenolics, anthocyanin and polymeric pigment in red wine is an important part of quality control in the wine industry. Precise and reliable measurement of phenolic compounds in wine is critical for making decisions during fermentation, maceration, pressing and blending. Harbertson et al. developed a comprehensive red wine phenolics assay in 2003.1 Traditionally this assay is performed using a cuvette-based UV-vis spectrophotometer. It is a time-consuming and
Cytotoxicity in Cells: Easy Determination Using Lonza ViaLight Plus and ToxiLight BioAssays on the SpectraMax L Microplate Luminometer
Molecular Devices
Bioluminescent cytotoxicity assays offer the user increased detection limits, speed, and accuracy, and have been well documented (Crouch et al., 1993). Healthy cells maintain a high constant ATP concentration in culture. During proliferation, the total ATP in the culture increases in line with cell number. Conversely, dying cells are unable to maintain their high ATP level, as synthesis becomes compromised, and so levels are seen to reduce. The level of ATP present within a culture is indicative
Microplate-Based Endotoxin Testing in GLP/GMP Environments with the VersaMax™ Absorbance Microplate Reader and Pyrochrome® Assay
Molecular Devices
Monitoring for contaminants is a critical step during the production process in the pharmaceutical and medical device industries. A frequent contaminant, endotoxin, can cause fever, inflammation, headache, nausea, and even death. Found in the cell wall of gram negative bacteria, endotoxin has routinely been detected by the sensitive and specific Limulus Amebocyte Lysate (LAL) assay. In the presence of endotoxins, LAL coagulates through an enzyme-mediated cascade, which has then been traditional
Heating on an Atlas Hotplate
Syrris Ltd
In the following experiments, different vessels were heated using the Atlas hotplate, with and without the Atlas Stacking Drybath. In every case, an external thermocouple probe has been used with the system to accurately measure “reaction” temperature.
Analysing Endotherms using Atlas
Syrris Ltd
This application note shows how atlas and reaction monitoring can be used to look at endothermic processes.
Tracking Exotherms using Atlas Reaction Monitoring
Syrris Ltd
This application note shows how atlas and reaction monitoring can be used to look at exothermic processes.
Reaction Monitoring with Atlas 1
Syrris Ltd
This application note reports the use of the atlas system to monitor the hydrolysis of acetic anhydride, a typical test reaction for exothermic processes.
Reaction Monitoring with Atlas 2
Syrris Ltd
This application note details an experiment to show the repeatability and scalability of reaction monitoring signals by using an electrical heater system.
Examples of FRX Applications for Demonstration
Syrris Ltd
FRX as a product offers a wide range of applications in a number of areas. To try and increase the exposure of the product to a wider audience, two standard demonstrations are detailed here. The first is a Wittig reaction showing the operation of an FRX200 system. The second is a separation of water and ethyl acetate demonstrating the operation of the FLLEX (Flow Liquid Liquid EXtraction module), for FRX300 or FRX400.
Cleaning Microreactors
Syrris Ltd
This application note gives hints and tips on cleaning & unblocking flow reactors, i.e. chips or tube based reactors. It is suggested that the whole document is read before attempting to unblock a reactor.
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