Corporate Banner
Satellite Banner
Medicinal Chemistry
Scientific Community
 
Become a Member | Sign in
Home>Events>This Event
  Events - July 2014


Biochemical Assays for Screening Workshop

09 Jul 2014 - 11 Jul 2014 - Hamburg, Germany



Bookmark and Share


Taking place over three days at the European ScreeningPort facility in Hamburg, the workshop will offer attendees the chance to participate in practical sessions using the latest technology available from the top screening equipment / reagent vendors in the pharmaceutical industry.

This is a must-attend event for anyone in the drug discovery industry to learn about screening technologies and discover what they can do for your company or laboratory.

Who should attend

• Scientists at all levels (undergraduates, postgraduates and laboratory based scientists within academic and industrial research organisations) who are engaged in early stage drug discovery and have an interest in the development, validation and utilisation of biochemical assays for screening against small molecule libraries.

• The course will include a series of lectures describing the screening compatible biochemical assays for use in drug discovery.

• The majority of the course will be laboratory based in which assays for targets that are currently actively being pursued for drug discovery purposes (kinases, histone deacetylases and proteases) will be developed, validated and screened against a small molecule library (known drugs). Selected Hit compounds will be evaluated in suitable Secondary assays.

Expected outcomes from the workshop

It is envisaged that upon completion of the course, attendees will have gained an insight into the key parameters to be considered when developing biochemical assays and performing small molecule screening, data analysis and validation of Hits in suitable Secondary assays.

Agenda Topics

•    Km Determination for Substrates
•    Aspects of Adaption of Assays for Screening of a Small Molecule Library (Known Drugs)
•    Choice of Biochemical Assay Development Projects: Kinase, Protease or Histone Deacetylase
•    Data Analysis and Classifying Compounds as Hits
•    IC50 Determination for Inhibitor, Signal Stability, Choice of Liquid Handling and Z’
•    Interferers
•    Kinetic Characterisation of Enzymes
•    Validation of Hits Selected from Screening Campaigns



Further information
Scientific News
Experimental Drug Cancels Effect from Key Intellectual Disability Gene
A University of Wisconsin—Madison researcher who studies the most common genetic intellectual disability has used an experimental drug to reverse — in mice — damage from the mutation that causes the syndrome.
Doubling Down on Dengue
HMS researchers have discovered two ways a compound blocks dengue virus.
Reprogramming Scorpion Venom
‘Twist of nature’ neutralizes toxin.
Tailoring a Suit for Tumor-Penetrating Cancer Meds
For more than a decade, biomedical researchers have been looking for better ways to deliver cancer-killing medication directly to tumors in the body.
Resurrecting an Abandoned Drug
Previously discarded drug shows promise in helping human cells in a lab dish fight off two different viruses.
Safer, Cheaper, Greener and More Efficient System for Organic Synthesis
The new medium not only supports organic synthesis it also produces considerably higher yields of product than pure organic solvents.
Fighting Prostate Cancer
Identifying the most promising compounds which can be used as medications for prostate cancer.
Collaboration to Develop Cancer Therapeutics
Major license agreement with Merck, enabled by Blavatnik Biomedical Accelerator, aims to develop therapy for most common form of acute leukemia.
Faster UVA Molecular Analysis Technology
There are people in the world – chemical engineers, astronomers, national defense scientists investigating an explosion – who need to know just what something is made of, down to the molecular level.
Scientists Synthesize Anti-Cancer Agent
A team led by Rice University synthetic organic chemist K.C. Nicolaou has developed a new process for the synthesis of a series of potent anti-cancer agents originally found in bacteria.
Scroll Up
Scroll Down
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,000+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,400+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!