The HT-4X centrifugal evaporator from Genevac provides optimised sample preparation capabilities for scientists working in the drug discovery environment. Built to the highest specifications, the HT-4X makes demanding applications routine. Corrosive vapours such as trifluoroacetic acid may be removed by the standard system and an inert purge option allows high safety evaporation of flammable solvents. In addition, the HT-4X can also be used to achieve high speed lyophilisation of HPLC fractions and solvents used for reformatting samples. The HT-4X is a high performance evaporator that combines ease of use, compactness, operational versatility and efficient sample processing. An innovative built-in dual chamber refrigerated condenser, that combines a powerful cryopump and solvent recovery system, together with extra powerful IR lamps, accelerates the speed of evaporation, even for high boiling point solvents such as DMSO. In addition, efficient chamber cooling between runs is particularly useful to protect thermally sensitive samples when run immediately after higher boiling point solvents. The system additionally offers an auto-defrosting condenser option and novel functions such as auto shutdown and auto-solvent selection, making it extremely easy to use. Genevac’s patented SampleGuard™ and Dri-Pure® technology is included to protect samples from overheating and bumping. Operated via an integral full colour screen the Genevac HT-4X offers comprehensive display of real-time data enabling rapid methods development across a wide range of applications. The easy-to-use system provides facility to store up to 99 evaporation methods making it ideal for multi-user environments.