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Combining Chemotherapy With Immune-Blocking Drug Could Stop Cancer Growing Back
Giving patients a drug that blocks part of the immune system from going into overdrive might help prevent cancer coming back in some people.
Researchers Pioneer Use of Capsules to Save Materials
Wax capsule delivery systems can simplify a wide range of chemistry transformations.
Photoredox Catalyst Unlocks New Pathways for Nickel Chemistry
Using a light-activated catalyst, researchers have unlocked a new pathway in nickel chemistry to construct carbon-oxygen (C-O) bonds that would be highly valuable to pharmaceutical and agrochemical industries.
Scientists Determine How Antibiotic Gains Cancer-Killing Sulfur Atoms
In a discovery with implications for future drug design scientists have shown an unprecedented mechanism for how a natural antibiotic with antitumor properties incorporates sulfur into its molecular structure, an essential ingredient of its antitumor activity.
Familiar Drugs May Block Ebola Virus Infection
A well-known class of molecules, many of which are already in use therapeutically, may be able to block the Ebola virus’s entry into cells and halt the disease in its tracks, according to researchers at the University of Illinois at Chicago.
New Extra ‘Sticky’ Microgel Could Revolutionise Bladder Cancer Treatment
Researchers have designed a new super-efficient way of delivering an anti-cancer drug which could extend and improve the quality of life for bladder cancer patients - and perhaps save lives.
Common Class of ‘Channel Blocking’ Drugs May Find a Role in Cancer Therapy
Discoveries in fruit flies prompt unusual treatment of patient with metastatic disease.
Common Medications Could Delay Brain Injury Recovery
Drugs used to treat common complaints could delay the recovery of brain injury patients according to research by University of East Anglia (UEA) and University of Aberdeen scientists, published today in Brain Injury.
Scientists Make Strides in Therapy Preventing Addiction Relapse
Single Injection of Drug Candidate Prevents Meth Relapse in Animal Models.
New Clot-Busting Treatments Target Number One Killer
Australian researchers funded by the National Heart Foundation are a step closer to a safer and more effective way to treat heart attack and stroke via nanotechnology.
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AMRI

Rising R&D costs, increasing expectations in the areas of productivity and quality, and a growing need to establish operations in close proximity to emerging markets are driving the international expansion of drug-discovery organizations. This global shift is driving new trends in the area of career development and hiring, such as the need for experienced scientific professionals at different locations all over the globe. Although the global pharmaceutical industry is going through significant changes, the role of medicinal chemistry in identifying and optimizing potential new drug candidates remains substantial. Going forward, current and future candidates in the area of medicinal chemistry and other scientific disciplines who have a willingness to work overseas may gain a competitive advantage when entering or advancing within the drug discovery field. 

During the past 10 years, there has been limited growth in the number of approved new chemical entities entering the marketplace in spite of a significant increase in overall R&D spending. For a number of reasons, R&D activities have also become more global during this time. As a result of this globalization associated with expanding international operations, there is an increased need for talent – principally with discovery and development skill sets – that may favor candidates who are willing to consider working in these non-traditional locations. 

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