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Scientific News
Drug Does Not Improve Set of Cardiovascular Outcomes for Diastolic Heart Failure
NIH-supported study finds drug does appear to reduce hospitalizations for diastolic heart failure.
Entirely Novel Strategy to Molecular Anticancer Therapy Tricks Malignant Cells
New drug prevents tumour growth by inhibiting the nucleotide sanitizing enzyme MTH1.
New Trial of Personalized Cancer Treatment Begins in Oxford
Phase I trial in Oxford will investigate a new drug, called CXD101.
Flow Microreactor Synthesis in Organo-Fluorine Chemistry
This review focuses on successful examples on synthesis and reactions of fluorine-containing molecules by the use of flow microreactor systems.
Reviewing Colchicaceae Alkaloids - Perspectives of Evolution on Medicinal Chemistry
Researchers have shown how thinking about evolution can influence selection of plant material in drug lead discovery.
New Drug Treatment Reduces Chronic Pain Following Shingles
New drug EMA401 reduce pain and did not cause any serious side effects.
Scripps' Scientists Develop Promising Drug Candidates for Pain and Addiction
Two new drug scaffolds offer researchers novel tools that act on the kappa opioid receptor.
World’s Tiniest Drug Cabinets could be Attached to Cancerous Cells for Long Term Treatment
Reservoirs of pharmaceuticals could be manufactured to bind specifically to infected tissue such as cancer cells for slow, concentrated delivery of drug treatments.
Malaria Drug Target Raises Hopes for New Treatments
Scientists identify way to stop malaria parasites from multiplying.
Tobacco, Drug Use in Pregnancy Can Double Risk of Stillbirth
NIH network study documents elevated risk associated with marijuana, other substances.

Drug-drug combinations made simple
Roderick L. Beijersbergen, Associate Professor Division of Molecular Carcinogenesis and Head NKI Robotics and Screening Center.

Druggability of Dynamic Protein-Protein Interfaces
Volkhard Helms, Universitat des Saarlandes, speaking at Discovery Chemistry Congress 2013.

Library Design for Tackling Protein-protein Interactions: The 2P2I Approach
Dr Philippe Roche, CNRS, speaking at Discovery Chemistry Congress 2013.

Approaches to the Discovery of Small-molecule MDM2-p53 Inhibitors
Dr Ian Hardcastle, Newcastle University, speaking at Discovery Chemistry Congress 2013.

How to Make Yeast Tremble and Suffer Energy Loss: Yeast Models for Prion and Mitochondrial Diseases
Professor Marc Blondel, Université de Bretagne Occidentale, speaking at Discovery Chemistry Congress 2013.

Towards the Systematic Exploration of Chemical Space: Design, Synthesis and Exploitation of Diverse Small Molecular Libraries
Dr Richard Doveston, University of Leeds, speaking at Discovery Chemistry Congress 2013.

Chemical Proteomics: Drug Targets, Drug Selectivity, MoA and Resistance
Dr. Guillaume Médard, Technische Universität München, speaking at Discovery Chemistry Congress 2013.

Continuous Flow Multi-Step Organic Synthesis - Methods and Applications
Tim Jamison, Professor at Massachusetts Institute of Technology, speaking at Flow Chemistry Congress.

Fragment Based de novo Ligand Design: A Valuable Optimisation Tool in Fragment Based Lead Discovery
Peter Johnson, University of Leeds, speaking at Discovery Chemistry Congress 2012.

The Versatility of Fragment Screening Approaches and the Application of Fragment Binding Information in Durg Discovery
Stefan Geschwindner, AstraZeneca, speaking at Discovery Chemistry Congress 2012.

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