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Scientific News
Novogen Announces Important Discovery in Regenerative Medicine Program
A key proof-of-concept step to develop drugs capable of stimulating the function of brain tissue stem cells.
Stanford Chemists Take Step Toward Solving Mystery of How Enzymes Work
Steven Boxer and his students have found that the electrostatic field within an enzyme accounts for the lion's share of its success.
New Class of Synthetic Molecules Mimics Antibodies
A Yale University lab has crafted the first synthetic molecules that have both the targeting and response functions of antibodies.
The Hunt for Botanicals
Herbal medicine can be a double-edged sword and should be more rigorously investigated for both its beneficial and harmful effects, say researchers writing in a special supplement of Science.
Novel Agent Decreases Neuropathic Pain in Patients with Type 2 Diabetes
Promising profile of disease modification and pain reduction leads to proof of concept trials.
Barrier-Breaking Drug May Lead to Spinal Cord Injury Treatments
NIH-funded scientists take first step towards developing promising new drug.
Two Drugs are No More Effective Than One to Treat Common Kidney Disease
NIH study finds limited kidney benefit from more rigorous blood pressure treatment.
Antibiotic Resistance Threatens Future of Modern Medicine
Overuse and misuse of antibiotics, one of the key contributors to antimicrobial resistance (AMR).
Computer Model Sets New Precedent in Drug Discovery
New computational model can precisely simulate, predict therapeutic protein behaviors to help zero in on ideal drug design candidates.
New Drug for Common Liver Disease Improves Liver Health
An experimental drug aimed at treating a common liver disease showed promising results and potential problems in a multicenter clinical trial funded by the NIH.

Biomarkers as Expression Signatures: Combinatorial Problem Solved with Gene Networks
Audrey Alexenko, Researcher, Stockholm Bioinformatics Centre, speaking at the Molecular Diagnostics World Congress 2009

Bioluminescent Cytochrome P450 Inhibition and Induction Assays: Comparisons to Conventional Methods
Jim Cali, Senior Scientist, Promega, speaking at ADMET Europe 2009

In silico Prediction of ADMET Properties
John Dearden, School of Pharmacy and Chemistry, Liverpool John Moores University, speaking as ADMET Europe 2009

Retigabine and Therapeutic Indications of Activating Neuronal KCNQ Voltage-Gated Potassium Ion Channels
Jim Wu, Head of Discovery Biology, Roche R&D Center, speaking at Ion Channel Targets 2008

Hypertension in P2Y2 Receptor-Deficient Mice is Caused by Constitutive Activation of ENaC
James Stockand, Associate Professor, University of Texas Health Science Center at Houston, speaking at Ion Channel Targets 2008

Mechanosensitivity, A Wide Open Field
Frederick Sachs, Distinguished Professor, New York State University at Buffalo, speaking at Ion Channel Targets 2008

Principles for 3D/4D Classification of Drugs
Vladimir Potemkin, Head of Organic Chemistry Department, Chelyabinsk State University, speaking at Virtual Discovery 2008

Molecular Dynamics Study of Amyloid Formation of Two Abl-SH3 Domain Peptides: Single and Multiple Beta-sheets
Inta Liepina, Principal Scientist, Latvian Institute of Organic Synthesis, speaking at virtual Discovery 2008

Novel Recombinant Peptide Toxin Fusion Proteins as Potential Therapeutics for the Treatment of Autoimmune Disease
Hung Nguyen, Principal Scientist, Amgen, speaking at Ion Channel Targets 2008

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