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Scientific News
Collaboration Leads to Possible Shortcut to New Drugs
The reaction, reported in Science, demonstrates how a carboxylic acid can be transformed into a very reactive site through use of a novel photoredox catalyst.
Catalysts That Mimic Enzymes Could Revolutionize Pharmaceutical Manufacturing
Structures made of polymer chains allow the catalysts to work in water.
Discovery of How Taxol Works Could Lead to Better Anticancer Drugs
The drug’s interference with the normal function of microtubules could help in designing better anticancer drugs.
Chemists Discover Cancer Drug Candidate Structure
Chemists at The Scripps Research Institute have determined the correct structure of a highly promising anticancer compound approved by the U.S. FDA for clinical trials in cancer patients.
Novel Drug Targets for Allergy Identified
Researchers have identified several target molecules which are suitable for the development of new allergy drugs.
Drug Does Not Improve Set of Cardiovascular Outcomes for Diastolic Heart Failure
NIH-supported study finds drug does appear to reduce hospitalizations for diastolic heart failure.
Entirely Novel Strategy to Molecular Anticancer Therapy Tricks Malignant Cells
New drug prevents tumour growth by inhibiting the nucleotide sanitizing enzyme MTH1.
New Trial of Personalized Cancer Treatment Begins in Oxford
Phase I trial in Oxford will investigate a new drug, called CXD101.
Flow Microreactor Synthesis in Organo-Fluorine Chemistry
This review focuses on successful examples on synthesis and reactions of fluorine-containing molecules by the use of flow microreactor systems.
Reviewing Colchicaceae Alkaloids - Perspectives of Evolution on Medicinal Chemistry
Researchers have shown how thinking about evolution can influence selection of plant material in drug lead discovery.

Alpha2* Nicotinic Acetylcholine Receptors as a Therapeutic Target for Memory Enhancement
Dr Katumi Sumikawa, University of California, speaking at Ion Channel Targets 2011.

Smooth Muscle Kv7 (KCNQ) Potassium Channels: Important New Therapeutic Targets
Professor Kenneth Byron, Loyola University Chigaco, speaking at Ion Channel Targets 2011.

Protons, Heat and Mechanical Force Converge to Gate Two-Pore Potassium Channels at the Selectivity Filter
Dr Slav Bagriantsev, University of California, speaking at Ion Channel Targets 2011.

Patent Pheromones: Attracting Money, Repelling Infringement, Prompting a Mating Response
Thomas Saunders, Of Counsel, Rissman Hendricks & Oliverio, speaking at Medchem Europe 2011.

Latent Hit Identification in Primary Screening Data with Compound Set Enrichment
Thibault Varin, PostDoctoral Fellow, Novartis, Speaking at Medchem Europe 2011.

Current Perspectives in Fragment Based Ligand Discovery
Roderick Hubbard, Professor, University of York, speaking at Medchem Europe 2011

Approach to Quick Lead Optimization Including Physicochemical and ADME Profiling
Pranas Japertas, Director, ACD Labs, Speaking at Medchem Europe 2011.

Renin Inhibitors: A Journey Through Polarity, Size and Potency
Olivier Bezençon, Chemistry Project Leader and Senior Group Leader, Actelion Pharmaceuticals, speaking at Medchem Europe 2011.

State-of-the-Art in Ligand-Based Virtual Screening
Jürgen Bajorath, Professor, Department of Life Science Informatics, University of Bonn, speaking at Medchem Europe 2011.

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