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Scientific News
Cancer Treatment with KU Origins Enters Second Clinical Trial
Cleave Biosciences has begun a Phase 1 clinical trial to evaluate CB-5083.
Grant will Help Develop More Powerful Disinfectants
$200,000 grant awarded to develop the next generation of antibacterial cleansers and disinfectants.
Artificially-intelligent Robot Scientist ‘Eve’ Could Boost Search for New Drugs
Eve, an artificially-intelligent ‘robot scientist’ could make drug discovery faster and much cheaper, say researchers writing in the Royal Society journal Interface.
Novogen Announces Important Discovery in Regenerative Medicine Program
A key proof-of-concept step to develop drugs capable of stimulating the function of brain tissue stem cells.
Stanford Chemists Take Step Toward Solving Mystery of How Enzymes Work
Steven Boxer and his students have found that the electrostatic field within an enzyme accounts for the lion's share of its success.
New Class of Synthetic Molecules Mimics Antibodies
A Yale University lab has crafted the first synthetic molecules that have both the targeting and response functions of antibodies.
The Hunt for Botanicals
Herbal medicine can be a double-edged sword and should be more rigorously investigated for both its beneficial and harmful effects, say researchers writing in a special supplement of Science.
Novel Agent Decreases Neuropathic Pain in Patients with Type 2 Diabetes
Promising profile of disease modification and pain reduction leads to proof of concept trials.
Barrier-Breaking Drug May Lead to Spinal Cord Injury Treatments
NIH-funded scientists take first step towards developing promising new drug.
Two Drugs are No More Effective Than One to Treat Common Kidney Disease
NIH study finds limited kidney benefit from more rigorous blood pressure treatment.

Patent Pheromones: Attracting Money, Repelling Infringement, Prompting a Mating Response
Thomas Saunders, Of Counsel, Rissman Hendricks & Oliverio, speaking at Medchem Europe 2011.

Latent Hit Identification in Primary Screening Data with Compound Set Enrichment
Thibault Varin, PostDoctoral Fellow, Novartis, Speaking at Medchem Europe 2011.

Current Perspectives in Fragment Based Ligand Discovery
Roderick Hubbard, Professor, University of York, speaking at Medchem Europe 2011

Approach to Quick Lead Optimization Including Physicochemical and ADME Profiling
Pranas Japertas, Director, ACD Labs, Speaking at Medchem Europe 2011.

Renin Inhibitors: A Journey Through Polarity, Size and Potency
Olivier Bezençon, Chemistry Project Leader and Senior Group Leader, Actelion Pharmaceuticals, speaking at Medchem Europe 2011.

State-of-the-Art in Ligand-Based Virtual Screening
Jürgen Bajorath, Professor, Department of Life Science Informatics, University of Bonn, speaking at Medchem Europe 2011.

‘Better Compounds Faster’ – The Development and Exploitation of a Desktop Predictive Chemistry Toolkit
John Cumming, Global Programme Manager for Predictive Chemistry, AstraZeneca R&D, speaking at Medchem Europe 2011.

Thermodynamics Guided Lead Discovery and Optimization
György M. Keseru, Head of Discovery Chemistry, Gedeon Richter, speaking at Medchem Europe 2011.

Enhancing Success Rates in Virtual Screening
Giulio Rastelli, Associate Professor in Medicinal Chemistry at the University of Modena, speaking at Medchem Europe 2011.

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