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Scientific News
Collaboration Leads to Possible Shortcut to New Drugs
The reaction, reported in Science, demonstrates how a carboxylic acid can be transformed into a very reactive site through use of a novel photoredox catalyst.
Catalysts That Mimic Enzymes Could Revolutionize Pharmaceutical Manufacturing
Structures made of polymer chains allow the catalysts to work in water.
Discovery of How Taxol Works Could Lead to Better Anticancer Drugs
The drug’s interference with the normal function of microtubules could help in designing better anticancer drugs.
Chemists Discover Cancer Drug Candidate Structure
Chemists at The Scripps Research Institute have determined the correct structure of a highly promising anticancer compound approved by the U.S. FDA for clinical trials in cancer patients.
Novel Drug Targets for Allergy Identified
Researchers have identified several target molecules which are suitable for the development of new allergy drugs.
Drug Does Not Improve Set of Cardiovascular Outcomes for Diastolic Heart Failure
NIH-supported study finds drug does appear to reduce hospitalizations for diastolic heart failure.
Entirely Novel Strategy to Molecular Anticancer Therapy Tricks Malignant Cells
New drug prevents tumour growth by inhibiting the nucleotide sanitizing enzyme MTH1.
New Trial of Personalized Cancer Treatment Begins in Oxford
Phase I trial in Oxford will investigate a new drug, called CXD101.
Flow Microreactor Synthesis in Organo-Fluorine Chemistry
This review focuses on successful examples on synthesis and reactions of fluorine-containing molecules by the use of flow microreactor systems.
Reviewing Colchicaceae Alkaloids - Perspectives of Evolution on Medicinal Chemistry
Researchers have shown how thinking about evolution can influence selection of plant material in drug lead discovery.

Chemogenomic Strategies to Expand the Bioactive Chemical Space
Edgar Jacoby, Group Leader, Novartis, speaking at MedChem Europe

Dynamic Combinatorial Library – an Integrated Approach for Direct Lead Discovery Using Chemical Fragments
Beining Chen, Senior Lecturer, University of Sheffield, speaking at MedChem Europe

Dynamic Combinatorial Library – an Integrated Approach for Direct Lead Discovery Using Chemical Fragments
Beining Chen, Senior Lecturer, University of Sheffield, speaking at MedChem Europe

Chemical Synthesis and Rapid Scale-Up in Continuous Flow Reactors
Paul Watts, Senior Lecturer, University of Hull, speaking at Advances in Synthetic Chemistry

Supported Organic, Nanometallic and Enzymatic Catalysis in Microreactors
Willem Verboom, Associate professor, Univ. of Twente, speaking at Advances in Synthetic Chemistry

Microwave-assisted Multi-component Syntheses of Heterocycles Initiated by Transition Metal Catalysis
Thomas J. J. Müller, Chair of Organic Chemistry, Heinrich-Heine-Universität Düsseldorf, speaking at Advances in Synthetic Chemistry

Scaling Out an SNAr Reaction in Microwave Flow Reactors
Jonathan Moseley, Associate Principal Scientist, AstraZeneca, speaking at Advances in Synthetic Chemistry

Novel Process Windows - Gateways to Sustainable and Intensified Process Chemistry
Volker Hessel, Professor, Eindhoven University, speaking at Advances in Synthetic Chemistry

A Roadmap for Successful Probe Discovery in an Academic Setting: The KU Experience
Rathnam Chaguturu, University of Kansas, Director, speaking at Probe Discovery 2010.

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