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Life of a Scientific Poster...
Pittcon 2015 Seminar: IC-HRAM For Metabo...Science with Sciex #4: SWATH™ Acquisitio...New Metabolomics Biomarker for Heart Fai...

Featured Products
Featured Product - PeakInvestigator™ Deconvolution & Centroiding Software
PeakInvestigator™ Deconvolution & Centroiding Software

Webcasts
Webcasts - Mass spectrometry based metabolomics in chemical and nanomaterial risk assessmentMass spectrometry based metabolomics in chemical and nanomaterial risk assessment
In this webinar, Mark Viant, Professor of Metabolomics at the University of Birmingham, will introduce the concepts of metabolomics as well as the challenges faced in chemical hazard assessment.
Webcasts - New Metabolomics Biomarker for Heart FailureNew Metabolomics Biomarker for Heart Failure
Philipp Schatz, Metanomics Health GmbH, speaking at Diagnostics & Biomarkers 2015.

Market Reports
Analytical Instrument Market in the US 2014-2018
Infinity Research

TechNavio's report focuses on the US and has been prepared based on an in-depth market analysis with inputs from industry experts.
Molecular Spectroscopy Market by Technology & Application - Forecast to 2018
MarketsandMarkets

Over the years, the molecular spectroscopy market, comprising instruments, consumables, and services, has witnessed various technological advancements. These advancements have led to a growth in the number of molecular spectroscopy applications.
Mass Spectrometry Market by Technology & Application - Global Trends & Forecast to 2018
MarketsandMarkets

The global mass spectrometry market witnesses high competitive intensity as there are many big and small firms with similar product offerings. These companies adopt various strategies to increase their market shares and to establish a strong foothold in the global market.
Liposomes
RI Technologies

This market insight report on liposomes gives an insight into global liposomes market. The report provides market analytics by application, and by therapeutic area.
Metabolomics
RI Technologies

This report gives an insight into Metabolomics Technologies - Combined/Integrated Systems, Hardware Systems for metabolic analytics, and Software Systems. Estimations and predictions for the total global Metabolomics Technologies' market are given by geographic regions encompassing United States, Canada, Europe, Asia-Pacific, and Japan.
Bioinformatics
RI Technologies

This report gives a market insight into products and services used in the bioinformatics industry. The market is analyzed by product and applications; Database, Software and Hardware form the product categories, finding applications in Genomics, Proteomics, Metabolomics, and other (Drug Discovery, Cheminformatics, and Pharmacogenomics).
Biomarkers
RI Technologies

This report on focuses on the different types of biomarkers and their impact on various disease areas. The study also provides global market analysis for biomarkers by disease area and by prominent biomarker identification technologies.
Biomarkers in Drug Discovery - Integration in Early Stage Promotes Use of Companion Diagnostics to Optimize Therapeutic Outcomes
Global Data

The report describes the history of biomarkers and their role in fulfilling the unmet needs of the conventional drug discovery process. The drivers and barriers for the biomarkers market, along with the key issues faced in the application of biomarkers in the drug discovery process, are highlighted.
Life Science Software 2013: Markets and Opportunities
Biopharm Reports

This reports into in the life science field examines the use of specialist software and databases relating to the conduct of PCR, DNA sequencing, DNA microarray, flow cytometry, mass spectrometry and disease biomarker studies. The studies were carried out to assist software developers and vendors to identify market opportunities in these fields.
Life Science Consumables 2013: Markets and Opportunities
Biopharm Reports

Techniques such as PCR, DNA microarray, DNA sequencing, mass spectrometry and flow cytometry have grown significantly in the last decade and by 2015 markets for these five areas are expected to exceed $50 billion, globally. In these and related fields, consumables are generally the second or third largest area in cost terms, after instrumentation.
Scientific News
Giant Panda Microbiome Poorly Adapted for a Bamboo Diet
Researchers have found that the microbiome of the Giant Panda lacks key bacterial species typically found in herbivores.
Infant Antibiotic use Linked to Adult Diseases
A new study has found a three-way link among antibiotic use in infants, changes in the gut bacteria and disease later in life.
Potential Forensic Uses for Human Microbiome
A recent study suggests microbial communities found on or in some sites in an individual's body can be used as fingerprint-like identifiers.
Ease of Weight Loss Influenced by Individual Biology
NIH study finds varied responses to calorie restriction in obese adults.
LECO Announces Special Events at ASMS
Company to host a series of events during the conference held at the America’s Center, Saint Louis, MO on May 31-June 4.
Metabolic Link Discovered Between Colon Cancer and Bacterial Biofilms
A research team writes in Cell Metabolism that they have uncovered a clue to how bacteria may promote some colon cancers.
Blood Markers Could Help Predict Outcome Of Infant Heart Surgery
New research suggests it may be possible to predict an infant’s progress following surgery for congenital heart disease by analysing a number of important small molecules in the blood.
Scherer to Receive Banting Medal for Diabetes Research
Medal recognizes significant, long-term contributions to the understanding, treatment, or prevention of diabetes.
Urine Profiles Provide Clues To How Obesity Causes Disease
Scientists have identified chemical markers in urine associated with body mass, providing insights into how obesity causes disease.
Cells Exercise Suboptimal Strategy to Survive
Rice University study shows it’s not always good for cells’ metabolism to work at peak efficiency.
Business News
SCIEX and Hepregen Announce Co-Marketing Agreement
Alliance establishes SCIEX and Hepregen as a one-stop solution provider for drug metabolism investigators.
Sciex, Hepregen Team up on Metabolite Identification Offering
This recently announced collaboration aims to provide practical solutions for drug metabolism researchers.
Quotient Clinical Reports Another Successful Year of Record Growth
Operating capacity set to more than double in response to rising demand.
UK-China Collaboration For Data Sharing In Metabolomics
The European Bioinformatics Institute, The Genome Analysis Centre (TGAC), BGI and GigaScience receive funding from BBSRC for a UK-China consortium in metabolomics data sharing.
UT Southwestern’s Dr. Philipp Scherer Receive Banting Medal
Dr. Scherer will receive the prestigious Medal for diabetes research.
Agilent Collaborate with National University of Singapore
Company to support NUS Medicine's research for safer, more effective medicine for heart disease.
CMXC Announces Additional Results of Preliminary Analysis of Metabolomic Assays
New findings reveal enhanced transport as well as utilization of glucose during a treatment.
Canada’s New Genomics Innovation Network Unveiled
10 “Nodes” located in BC, Alberta, Ontario and Quebec to provide leading-edge technologies to researchers across Canada.
SCIEX and Mass Consortium Corporation Announce Exclusive Reseller Agreement
SCIEX to provide customers with XCMSplus software solution for simplified and accelerated metabolomics workflows.
CMXC Announces Results of Preliminary Analysis of Metabolomic Assays
Analysis of metabolomic assays taken during the Phase 1 pilot clinical trial.

Events
63rd ASMS Conference on Mass S
31 May 2015
63rd ASMS Conference on Mass S ...
More information
Webinar: Mass spectrometry bas
11 Jun 2015
Webinar: Mass spectrometry bas ...
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Metabolism in Cancer & Stromal
08 Sep 2015
Metabolism in Cancer & Stromal ...
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Diabetes Therapy & Management
16 Nov 2015
Diabetes Therapy & Management ...
More information

ePosters
"In-vitro studies on hydroxamic acid- CT DNA binding"
Research Scholar

In vitro studies of five the interaction between five different derivatives of hydroxamic acids, N-phenyl 2,4dichloro phenoxybutyro, N-m-tolyl 2,4 dichlorophenoxyglutero, N-m-tolyl-4-chlorophenoxyaceto, N-m-chloro-phenyl-tertiarybutylbenzo and N-p-tolyl-iso-valero hydroxamic acids and calf thymus DNA was investigated under simulated physiological condition.
MsCompare: An Untargeted LC & GC/MS Metabolomics Platform for Quality Control, Precise Deconvolution and Data Analysis
MsMetrix, the Netherlands

A GC/MS or LC/MS workflow for Metabolomics applications includes a number of distinct steps: experimental design, sampling, sample preparation, data acquisition, data processing, deconvolution, identification and data interpretation.

The MsXelerator software includes Quality Control procedures and Analysis of Variance (ANOVA) to properly control each step in this workflow and to obtain reliable results for both quantitation and identification.
Gut Microbial Metabolites and Hepatic Xenobiotic Metabolism: A High Throughput Screening Approach
University of Reading, AstraZeneca

This poster highlights the combination of metabonomics and high throughput screening by the identification of gut microbial metabolites and a screening assay designed to determine their cytotoxicity to liver-like cell cultures.
Searching for Urinary Biomarkers of Exposure to Heterocyclic Amines (HCAs)
Kingston University, National Food Institute, Technical University of Denmark, Lund University

Heterocyclic amines (HCAs) are foodborne carcinogens present in cooked meat and fish, mainly. Metabolites of HCAs have been determined in urine from volunteers following a controlled meal.
Metabolic Stability Assay Using Human Hepatocyte Co-cultures and Integrated Qualitative/Quantitative High Resolution Mass Spectrometry
QPS, Hepregen Corporation

Purpose: To investigate Sequential Window Acquisition of all Theoretical fragment ion spectra (SWATH™) based integrated qualitative and quantitative (qual/quant) assay for simultaneous metabolic stability and metabolite profiling assessments.
Mixtures Analysis of Complex Mixtures
Mestrelab Research

We describe an NMR method to quantify mixture components in wine, edible oils, etc. The method is fully customizable, and amenable to high throughput operation.
A Complete Wine Analysis Using Multiplets Detection
1Mestrelab Research, www.mestrelab.com; 2Institut Heidger, Germany, www.institut-heidger.de

NMR mixtures analysis can be used to determine the concentration of key components in wine. Here we show the analysis using SMA from Mestrelab.
DPPH scavenging activities of selected flavonoids and their mixtures
(1) Department of Pharmacognosy and Botany, Faculty of Pharmacy, Comenius University in Bratislava, Slovakia

The aim is to identify the ati-oxidant activity of selected flavonoids (quercetin, luteolin and galangin) and their mixtures using DPPH method including their synergistic or antagonistic interactions.
Correlation between plasma levels of lutein and oxidized low density lipoproteins: a short human intervention study
Università Politecnica delle Marche

The increase of plasma carotenoids, in particular lutein, after dietary treatment for two weeks is associated with a significant protective effect against lipid peroxidation of plasma lipoproteins.
Automatic Characterization of Lipids Using Charge Remote Fragmentation Ions and Peaks Characteristic of Fatty Acid Fragmentation From MALDI MS/MS Data
(1)PREMIER Biosoft, Indore, India; (2)PREMIER Biosoft, Palo Alto, U.S.A; (3)AB SCIEX, Darmstadt, Germany; (4)AB SCIEX, Framingham, U.S.A.

Automated identification of lipids using CRF ions and high energy MS/MS fragment ions and novel software.
Application Notes
Qualitative and Quantitative Characterization of the Metabolome, Lipidome, and Proteome of Human Hepatocytes Stably Transfected with Cytochrome P450 2E1 Using Data Independent LC/MS
Waters Corporation

Drug toxicity is a major reason for the failure of candidate pharmaceuticals during their development. Therefore, it is important to realize the potential for toxicity in a timely fashion. A label-free multi-omics approach has been applied for the analysis of the transfected human hepatocyte cells by implementing LC/HDMSE, providing both qualitative and quantitative information within a single experiment.
TransOmics Informatics Powered by Nonlinear Dynamics
Waters Corporation

This application note introduces the workflow of TransOmics Informatics Software that has been specifically developed for the larger scale analysis of ion mobility MS data from proteomics and metabolomics data sets, comprising technical and biological replicates.
Quantitative Determination of Total Bile Acids with a Thermo Scientific Varioskan Flash Multimode Reader Using a Kinetic Enzyme Cycling Assay
Thermo Fisher Scientific

Serum total bile acids (TBA) level is a long-established and accepted indicator of liver diseases. This application note presents a simple photometric measurement of serum TBA.
Optimization of Instrument Settings and Measurement Parameters for Kinetic Fluorometric and Luminometric Assays
Thermo Fisher Scientific

When fluorometric and luminometric assays are performed in microplate format, a high number of samples can be analyzed at a time. The speed of the reaction kinetics of the assay determines the requirements for the detection instrument and measurement parameters for achieving the best possible performance of the assay.
Pipetting performance of Thermo Scientific Finnpipette F2 in combination with Thermo Scientific Finntip Flex
Thermo Fisher Scientific

The Finnpipette® F2 product family has been designed by taking into account the demands of today´s laboratory work and the require¬ments of the end users. It offers superior comfort, performance, reliability and repeatability in one of the lightest pipettes available.
Using a Thermo Scientific Microplate Photometer to Choose an Optimum Reagent for Cytotoxicity Assays
Thermo Fisher Scientific

A number of different reagents can be used to perform photometric cell proliferation and viability assays. A microplate photometer can quickly determine which reagent is the best choice for an assay and then optimize the assay. Significant time savings and productivity gains can be achieved with this tool.
Ergonomics and Usability Study of Thermo Scientific Finnpipette F1 and F2 Pipettes
Thermo Fisher Scientific

The objective of the study was to evaluate the ergonomics and usability of six manual, singlechannel pipettes. This was done by measuring the load and strain symptoms exhibited by workers’ muscles and joints, and evaluating the usability features of pipettes in a simulated work situation.
Promega’s ADP-Glo™ Kinase Assay performed on BMG LABTECH’s PHERAstar FS and POLARstar Omega
BMG Labtech

The PHERAstar FS as well as the POLARstar Omega offer the ability to perform the ADP-Glo™ assay from Promega in a 384-well format. The ADP-Glo™ Kinase Assay is a homogenous luminescent assay to detect ADP in concentrations ranging from 1 mM to 0.01 µM. Instrument settings and standard ATP/ADP curves over a wide concentration range are presented for both the PHERAstar FS and the POLARstar Omega.
RADAR, a Xevo TQ-S function, combined with Low-High pH UPLC Screening for Fast, Simple Bioanalysis Methods Development
Waters Corporation

Here, we demonstrate the productivity gains possible with Xevo TQ-S for use in bioanalytical methods. Xevo TQ-S employs a unique RADAR functionality to collect data in the time scale of a narrow 1- to 2-second peak.
The Transcreener® ADP2 FI Assay performed on PHERAstar and Omega microplate readers
BMG LABTECH


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