EMBO | EMBL Symposium: Frontiers in Metabolism: From Molecular Physiology to Systems Medicine
17 Nov 2014 - 20 Nov 2014 - Heidelberg, Germany
This symposium will offer an integrated view of metabolism, highlighting the emerging concept that metabolism exerts an important homeostatic role on multiple pathways involved in human disease.
Conversion and processing of small molecules by cellular metabolic networks provides the cell with the necessary nutrients, biomass precursors and energy resources. Metabolism has therefore traditionally been seen as a downstream effector layer in the regulatory architecture of the cell. Recent work, however, revealed that metabolism commands cellular and organismal physiology and is closely intertwined with multiple signalling pathways.
This symposium will bring together leading researchers from a variety of disciplines and disease areas to stimulate cross-fertilising discussions and exchanges, offering an integrated view of metabolism and highlighting the emerging concept that metabolism exerts an important homeostatic role on multiple pathways involved in human disease, including tumour cell growth, inflammation, neuronal functions and epigenetic reprogramming.
Topics covered include:
• Mitochondria and metabolism
• Large-scale analysis of metabolism across species
• Metabolic sensors and effectors
• Stress pathways and metabolic homeostasis
• Stem cells, cancer and metabolism
• Metabolism and aging