Tissue of Origin Determines Cancer-associated CpG Island Promoter Hypermethylation Patterns
Published: Friday, October 05, 2012 Last Updated: Friday, October 05, 2012
Meehan, Sproul and co-workers conclude that general aberrant promoter hypermethylation in cancer does not promote tumorigenesis, but instead reinforces transcription repression inherited from pre-cancerous tissue.
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