Corporate Banner
Satellite Banner
Metabolomics & Lipidomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Study Explains how Bread Consumption can Improve Cardiovascular Health

Published: Friday, November 30, 2012
Last Updated: Friday, November 30, 2012
Bookmark and Share
Researchers identify metabolic factors related to bread's beneficial effects on cardiovascular health.

The study has been led by the professor Rafael Llorach, Ramon y Cajal researcher from the Department of Nutrition and Bromatology at the Faculty of Pharmacy and from the Food and Nutrition Torribera campus of the UB. This new research identified the metabolic factors which are possibly related to bread’s beneficial effects on lipid profile, and on the cardiovascular health of its consumers.
 The work, which is part of the Functional Foods Consolider-Ingenio Project and is promoted by the initiative Pan Cada Día, use techniques of metabolomics in order to analyse the impact of bread consumption (white and wholemeal) in a population sample made up of 275 advanced years volunteers who are in high cardiovascular and are take part in the study PREDIMED.

According to the professor Rafael Llorach, “the data obtained in the study indicate that daily bread consumption, especially wholemeal one, as an element of a balanced diet, is associated to a healthier lipid profile that shows lower insulin blood concentrations”. In the opinion of the professor Cristina Andrés-Lacueva, co-director of the project and head of the Research Group on Biomarkers and Nutritional and Food Metabolomics, “the metabolomics study drove us to identify the potential metabolic factors hid behind the positive effects that bread consumption has on the lipid profile and which can be determinant to be in a better cardiovascular health”. To be precise, the authors of the study identified a metabolite related to PPAR-alfa activity (a nuclear receptor involved in lipid metabolism which is raised in wholemeal bread consumers).

A healthier lipid profile

The study points out that people who daily consumes bread, white or wholemeal, show a healthier lipid profile —lower levels of LDL cholesterol and higher levels of HDL cholesterol— than the people who consume it sporadically or don’t consume it. The study also reveals that regular bread consumption is associated with a lower insulin concentration. “This is a really important data, when the body does not answer in a correct way to the insulin’s action, glucose cannot reach the inner part of cells and it is accumulated in blood”, explains Andrés-Lacueva. This mechanism —insulin resistance— is a key pathological process in the development of type 2 diabetes mellitus, also associated with a high risk of cardiovascular disease.

The results of the study coincide with other scientific works that also talk about a possible prevention effect of fibre consumption —especially the wholemeal ones— against the development of insulin resistance. Moreover, this study shows the regular consumption of bread, a good source of carbohydrates, vitamins, minerals and fibre, what represents an increase in the consumption of carbohydrates is not related to an increase of body weight.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 4,000+ scientific posters on ePosters
  • More than 5,300+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Metabolite Promotes Cancer Cell Transformation
Researchers have identified a metabolite that promotes cancer cell transformation and colorectal cancer spread.
Gut Bacteria Affect Our Metabolism
Study confirms, mice that receive gut bacteria transplants from overweight humans gain more weight than mice transplanted with gut bacteria from normal weight subjects.
The Benefits of a Mediterranean-style Diet
A Western-style diet, with more omega-6 fatty acids than the Mediterranean, dysregulates lipid signaling in aged mice and promotes inflammation.
Gut Bacteria Control Glucose Metabolism
Researchers have uncovered a link between the immune system, gut bacteria and glucose metabolism.
Peer Review is in Crisis, But Should be Fixed, Not Abolished
After the time to get the science done, peer review has become the slowest step in the process of sharing studies, and some scientists have had enough.
Plants Modulate Metabolite Accumulation at Organ Level
Scientists develop computational metabolomic approach to measure metabolic diversity in different plant tissues.
Gut Microbiome Linked to Inflammatory Proteins
Study looking at influence of genetics, microbiome and environment on immune response links intestinal microbial population to production of inflammatory proteins.
How it Works: Advanced Data Analysis Using Visualization
Visualisation of data can be used to help molecular biologists tackle the vast datasets their experiments create.
Cell Metabolism Linked to Spread of Cancer
Scientists discover macrophage metabolism can be attuned to prevent the spread of cancer.
Integrated Omics Analysis
Studying multi-omics promises to give a more holistic picture of the organism and its place in its ecosystem, however despite the complexities involved those within the field are optimistic.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
4,000+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,300+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!