Corporate Banner
Satellite Banner
Metabolomics & Lipidomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Patti Wins Sloan Research Fellowship

Published: Thursday, February 20, 2014
Last Updated: Wednesday, February 19, 2014
Bookmark and Share
Award honors outstanding early-career scientists.

The Alfred P. Sloan Foundation has announced Feb. 17th that WUSTL’s Gary Patti has been awarded a 2014 Sloan Research Fellowship. He is among 126 outstanding U.S. and Canadian researchers selected as fellowship recipients this year.

Awarded annually since 1955, the fellowships are given to early-career scientists and scholars whose achievements and potential identify them as rising stars, the next generation of scientific leaders.

“For more than half a century, the Sloan Foundation has been proud to honor the best young scientific minds and support them during a crucial phase of their careers when early funding and recognition can really make a difference,” said Dr. Paul L. Joskow, President of the Alfred P. Sloan Foundation. “These researchers are pushing the boundaries of scientific knowledge in unprecedented ways.”

“I am pleased and excited that Gary has been named a Sloan Fellow,” said William Buhro, PhD, professor and chair of chemistry. “Patti is a pioneer in the rapidly developing field of metabolomics, in which the wide arrays of small-molecule metabolites in biological systems are profiled. Metabolomics presents a massive data-analysis challenge, to which Gary is contributing new technologies. He is also applying his new metabolomics technologies to study the biochemistry of disease states, which will advance medical therapies.”

“The goal of metabolomics is to take a urine, blood or tissue sample, analyze it with an instrument called a mass spectrometer, and acquire a complete profile of all of the small molecules in the sample,” said Patti, PhD, assistant professor in the departments of chemistry, genetics and medicine. The profile might reveal whether the sample donor is ill, at risk of developing a disease, has been exposed to a toxin, or is unable to tolerate a drug therapy.

Metabolomics has already provided unparalleled insight into previously opaque illnesses, such as chronic pain. “We identified a molecule that, prior to our studies, was not known to be a naturally occurring compound. We have demonstrated that this molecule is an important player in mediating chronic pain, and this has opened up new avenues for therapies that could help millions of people,” Patti said.

His lab is also hot on the trail of sarcopenia, the muscle wasting that occurs in some elderly patients and leads to “fraility” that has also resisted scientific inquiry in the past. They identified six small molecules associated with aging in Caenorhabditis elegans, a worm that scientists use as a model system.

Two of these compounds change as a function of age in healthy human skeletal tissue and may be involved in sarcopenia. In the meantime the group is establishing a library of metabolite levels in long-lived model organisms.

Past Sloan Research Fellows include physicist Richard Feynman and game theorist John Nash. Since the beginning of the program in 1955, 42 fellows have received a Nobel Prize in their respective field, 16 have won the Fields Medal in mathematics, 13 have won the John Bates Clark Medal in economics, and 63 have received the National Medal of Science.

Scientists in eight scientific and technical fields-chemistry, computer science, economics, mathematics, evolutionary and computational molecular biology, neuroscience, ocean sciences, and physics-are eligible for the awards.

The fellowships are awarded through close cooperation with the scientific community. Candidates must be nominated by their fellow scientists, and winning fellows are selected by an independent panel of senior scholars on the basis of a candidate’s independent research accomplishments, creativity, and potential to become a leader in his or her field.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,900+ scientific posters on ePosters
  • More than 4,200+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Study: Can Vitamin D Slow Heart Complications from Diabetes?
Researchers evaluate whether vitamin D can slow the development of cardiovascular problems in African Americans.
Thursday, May 15, 2014
Scientific News
Cancer Cells Kill Off Healthy Neighbours
Cancer cells create space to grow by killing off surrounding healthy cells, according to UK researchers working with fruit flies.
Future of Medicine Could be Found in a Tiny Crystal Ball
A Drexel University materials scientist has discovered a way to grow a crystal ball in a lab. Not the kind that soothsayers use to predict the future, but a microscopic version that could be used to encapsulate medication in a way that would allow it to deliver its curative payload more effectively inside the body.
Toxicity Testing With Cultured Liver Cells
Microreactor replaces animal testing.
Proteins Seek, Attack, Destroy Tumor Cells in Bloodstream
Using white blood cells to ferry potent cancer-killing proteins through the bloodstream virtually eliminates metastatic prostate cancer in mice, Cornell researchers have confirmed.
Why Do Some Infections Persist?
In preparing for the possibility of an antibiotic onslaught, some bacterial cultures adopt an all-for-one/one-for-all strategy that would make a socialist proud, University of Vermont researchers have found.
Flipping Molecular 'Switch' May Reduce Nicotine's Effects in the Brain
Scientists at The Scripps Research Institute (TSRI) have discovered that a lipid (fat molecule) in brain cells may act as a “switch” to increase or decrease the motivation to consume nicotine.
TSRI Team Comes Together with Rare Disease Community
Don’t worry, science fiction fans, the machines aren’t taking over quite yet. It turns out humans still beat computers at reading and comprehending text.
Magnesium Intake May Reduce Pancreatic Cancer Risk
Indiana University researchers have found that magnesium intake may be beneficial in preventing pancreatic cancer.
Gut Microbes: Burning Calories While You Sleep?
Study links changes in gut bacteria to lower resting metabolic rate and weight gain in mice.
Cooperating Bacteria Isolate Cheaters
Bacteria, which reciprocally exchange amino acids, stabilize their partnership on two-dimensional surfaces and limit the access of non-cooperating bacteria to the exchanged nutrients.
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,200+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!