Corporate Banner
Satellite Banner
Metabolomics & Lipidomics
Scientific Community
Become a Member | Sign in
Home>News>This Article

Study: Can Vitamin D Slow Heart Complications from Diabetes?

Published: Thursday, May 15, 2014
Last Updated: Thursday, May 15, 2014
Bookmark and Share
Researchers evaluate whether vitamin D can slow the development of cardiovascular problems in African Americans.

Researchers at Washington University School of Medicine in St. Louis are evaluating whether vitamin D can slow the development of cardiovascular problems in African Americans with diabetes. They are more likely to die from cardiovascular disease than Caucasians with diabetes.

The researchers are seeking to enroll about 90 African Americans who are 45 to 80 years old and have type 2 diabetes. Study volunteers must not have heart disease or have suffered a stroke.

“Cardiovascular disease is a major health problem and cause of mortality in African Americans,” said Carlos Bernal-Mizrachi, MD, the study’s principal investigator. “Compared to Caucasians, African Americans suffer disproportionately from type 2 diabetes and heart disease.”

Nationally, African Americans with diabetes are 36 percent more likely than Caucasians with diabetes to die of cardiovascular disease. In past studies, Bernal-Mizrachi has found that low levels of vitamin D can double the risk of cardiovascular disease in patients with type 2 diabetes. His research also shows that blood vessels near the heart are less likely to clog in people who get adequate levels of the key vitamin.

Study volunteers will be screened at the School of Medicine to determine their vitamin D status. Those with low vitamin D levels will be asked to return for a second assessment, during which investigators will evaluate participants’ risk for coronary heart disease by measuring electrolyte levels, kidney function, blood cell counts, average blood sugar levels and cholesterol levels.

“In general, vitamin D deficiency is more common among African Americans, and that may help explain why they are so much more likely than Caucasians to have severe cardiovascular complications related to diabetes,” said Bernal-Mizrachi, associate professor of medicine and of cell biology and physiology.

Volunteers who meet the study’s criteria will be randomly assigned to one of two groups. Those in the first group will take 600 international units of vitamin D daily to try to raise their levels of the vitamin to the standard recommended for good health. Participants in the second study group will take 4,000 international units of the vitamin daily.

Subjects will be evaluated about every two months to measure blood sugar levels, hypertension, heart function and various markers of inflammation - all risk factors for heart disease.

“Compared to other potential interventions, vitamin D is very inexpensive and doesn’t have many known side effects,” said Bernal-Mizrachi. “We believe vitamin D could have a very big impact if the study shows that it can prevent or delay heart problems in African Americans with diabetes.”

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Patti Wins Sloan Research Fellowship
Award honors outstanding early-career scientists.
Thursday, February 20, 2014
Scientific News
Gut Microbes Signal to the Brain When They're Full
Don't have room for dessert? The bacteria in your gut may be telling you something.
Turning up the Tap on Microbes Leads to Better Protein Patenting
Mining millions of proteins could become faster and easier with a new technique that may also transform the enzyme-catalyst industry, according to University of California, Davis, researchers.
Drug May Prevent Life-Threatening Muscle Loss in Advanced Cancers
New data describes how an experimental drug can stop life-threatening muscle wasting (cachexia) associated with advanced cancers and restore muscle health.
Cancer-Fighting Tomato Component Traced
The metabolic pathway associated with lycopene, the bioactive red pigment found in tomatoes, has been traced by researchers at the University of Illinois.
Circadian Clock Controls Insulin and Blood Sugar in Pancreas
Map of thousands of genes suggests new therapeutic targets for diabetes.
Cellular Stress Process Identified in Cardiovascular Disease
Combining the investigative tools of genetics, transcriptomics, epigenetics and metabolomics, a Duke Medicine research team has identified a new molecular pathway involved in heart attacks and death from heart disease.
Predicting Adverse Drug Reactions with Higher Confidence
A new integrated computational method helps predicting adverse drug reaction—which are often lethal—more reliably than with traditional computing methods.
A New Way to Starve Lung Cancer?
Metabolic alterations in lung cancer may open new avenues for treating the disease.
Evidence of How Incurable Cancer Develops
Researchers in the West Midlands have made a breakthrough in explaining how an incurable type of blood cancer develops from an often symptomless prior blood disorder.
Building a Better Liposome
Computational models suggest new design for nanoparticles used in targeted drug delivery.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos