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Scientific News
Metabolic Mystery Solved, Lending Insight Into Lafora Disease
Scientists at the University of Kentucky College of Medicine have determined how an enzyme essential for energy metabolism functions, solving a mystery eluding molecular biologists for decades.
First Major Analysis Of Human Protein Atlas Published
A research article published in Science presents the first major analysis based on the Human Protein Atlas, including a detailed picture of the proteins that are linked to cancer, the number of proteins present in the bloodstream, and the targets for all approved drugs on the market.
Chestnuts Roasting On An Open Fire
ORNL work with scientists funded by The American Chestnut Foundation confirms increased blight-resistance of former forest giant.
Metabolomics Data Normalization with EigenMS
In this study, a singular value decomposition-based method, called EigenMS, for normalization of metabolomics data was tested.
Circadian Variation Of The Human Metabolome
Real-time breath analysis was used to study circadian metabolism.
Discovery Links Shift In Metabolism To Stem Cell Renewal
Mouse cells exposed to the metabolite alpha-ketoglutarate became more likely to renew themselves.
Bridging Quantitative Analysis and Untargeted Metabolomics
Untargeted metabolomics has become a popular tool in metabolite biomarker discovery and in the evaluation of metabolic pathway changes associated with disease.
Light-activated Drug Could Reduce Side Effects of Diabetes Medication
Scientists have created a drug for type 2 diabetes that is switched on by blue light, which they hope will improve treatment of the disease.
Getting Metabolism Right
Analysis of 89 models of metabolic processes finds flaws in 44 of them — but suggests corrections.
Biologists Find An Early Sign Of Cancer
Patients show boost in certain amino acids years before diagnosis of pancreatic cancer.

Challenges in the Development of Tissue Biomarkers
Steven Hewitt, Chief, Tissue Array Research Program, National Cancer Institute, Maryland, speaking at Microarray World Congress 2009

Immunoprofiling of Cancer-Specific Antibodies on Protein Microarrays of Novel Tumor Antigens
Michael Tainsky, Professor, Wayne State University, speaking at Microarray World Congress 2009

Genome-wide Profiling of DNA Methylation Patterns in Colon Cancers and its Utility in Biomarker Development for Early Detection and Prognosis
Sungwhan An, Chief Scientific Officer, Genomictree, speaking at Microarray World Congress 2009

The Future Impact of Proximity Ligation Assays in Cancer Diagnostics Through Senstive And Multiplexed Protein-based Biomarker Assays in Plasma and Tissue Samples
Simon Fredriksson, Chief Scientific Officer, Olink, speaking at Molecular Diagnostics Europe 2009

Detection of Angiogenic Growth Factor by Microcantilever Biosensors
Riccardo Castagna, PhD Student, Politecnico di Torino, speaking at Molecular Diagnostics Europe 2009

Information Integration and Biological Discovery
John Quackenbush, Professor, Harvard School of Public Health, speaking at the Molecular Diagnostics World Congress 2009

CYP Poor Metaboliser Genotyping on the Agilent Bioanalyzer and Clinical Application
Irina Piatkov, Senior Hospital Scientist, Diversity Health Institute, speaking at the Molecular Diagnostics World Congress 2009

Biomarkers as Expression Signatures: Combinatorial Problem Solved with Gene Networks
Audrey Alexenko, Researcher, Stockholm Bioinformatics Centre, speaking at the Molecular Diagnostics World Congress 2009

SOSA and Parallel in silico Screening: Merging Medicinal Chemistry Tradition with a Modern Computational Approach
Thierry Langer, CEO, Prestwick Chemicals, speaking at MedChem Europe 2009

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