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Scientific News
Metabolic Mystery Solved, Lending Insight Into Lafora Disease
Scientists at the University of Kentucky College of Medicine have determined how an enzyme essential for energy metabolism functions, solving a mystery eluding molecular biologists for decades.
First Major Analysis Of Human Protein Atlas Published
A research article published in Science presents the first major analysis based on the Human Protein Atlas, including a detailed picture of the proteins that are linked to cancer, the number of proteins present in the bloodstream, and the targets for all approved drugs on the market.
Chestnuts Roasting On An Open Fire
ORNL work with scientists funded by The American Chestnut Foundation confirms increased blight-resistance of former forest giant.
Metabolomics Data Normalization with EigenMS
In this study, a singular value decomposition-based method, called EigenMS, for normalization of metabolomics data was tested.
Circadian Variation Of The Human Metabolome
Real-time breath analysis was used to study circadian metabolism.
Discovery Links Shift In Metabolism To Stem Cell Renewal
Mouse cells exposed to the metabolite alpha-ketoglutarate became more likely to renew themselves.
Bridging Quantitative Analysis and Untargeted Metabolomics
Untargeted metabolomics has become a popular tool in metabolite biomarker discovery and in the evaluation of metabolic pathway changes associated with disease.
Light-activated Drug Could Reduce Side Effects of Diabetes Medication
Scientists have created a drug for type 2 diabetes that is switched on by blue light, which they hope will improve treatment of the disease.
Getting Metabolism Right
Analysis of 89 models of metabolic processes finds flaws in 44 of them — but suggests corrections.
Biologists Find An Early Sign Of Cancer
Patients show boost in certain amino acids years before diagnosis of pancreatic cancer.

Utilizing GC and GCxGC Coupled with Time-of-Flight Mass Spectroscopy (TOMFS) for the Analysis of Metabolomic Samples
Mark Libardoni, Technical Director - Life Science and Chemical Analysis Centre, LECO Corporation, speaking at Advances in Metabolic Profiling

Alterations in Cardiolipin Profile Link Diabetic Cardiomyopathy and Mitochondrial Dysfunction in Murine Models of Diabetes: A Shotgun Lipidomics Study
Xianlin Han, Washington University, speaking at Advances in Metabolic Profiling 2007

Moving Metabolic Profiling from Mouse to Human and from Laboratory into the Clinic
Agnieszka Lichanska, Lecturer, University of Queensland, speaking at Advances in Metabolic Profiling 2007

Intergration of Isotopomer-based Metabolomics with Functional Genomics
Teresa Fan, Assistant Professor, University of Louisville, speaking at Advances in Metabolic Profiling 2007

Metabolomics Strategy to Identify Tissue Specific Drug Effects
Matej Orešic, Chief Research Scientist, VTT Technical Research Centre, speaking at the European Biomarker Summit, 2007

Novel Biomarker Discovery Using Metabolomics
Felice de Jong, Director, Metabolon Inc. speaking at the European Biomarkers Summit 2006.

LC/MS/MS Solutions for Targeted and Non-Targeted Small Molecule and Protein Biomarker Discovery, Verification and Validation
Henri Snijders, European Marketing Manager Small Molecules, Applied Biosystems speaking at the European Biomarkers Summit 2006.

Novel Approach to Active Metabolite Identification Allowing Early Access to Metabolic Profiling Studies to Improve Lead Candidate Selection
Dr. Danny van Elswijk, Screening Director, Kiadis BV, speaking at Advances in Metabolic Profiling 2005.

Identification of Major Metabolism Regulators from Metabolic Profiles
Dr. Anton Yuryev, Executive Director of Application Science, Ariadne Genomics Inc., speaking at Advances in Metabolic Profiling 2005.

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