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Scientific News
Metabolic Mystery Solved, Lending Insight Into Lafora Disease
Scientists at the University of Kentucky College of Medicine have determined how an enzyme essential for energy metabolism functions, solving a mystery eluding molecular biologists for decades.
First Major Analysis Of Human Protein Atlas Published
A research article published in Science presents the first major analysis based on the Human Protein Atlas, including a detailed picture of the proteins that are linked to cancer, the number of proteins present in the bloodstream, and the targets for all approved drugs on the market.
Chestnuts Roasting On An Open Fire
ORNL work with scientists funded by The American Chestnut Foundation confirms increased blight-resistance of former forest giant.
Metabolomics Data Normalization with EigenMS
In this study, a singular value decomposition-based method, called EigenMS, for normalization of metabolomics data was tested.
Circadian Variation Of The Human Metabolome
Real-time breath analysis was used to study circadian metabolism.
Discovery Links Shift In Metabolism To Stem Cell Renewal
Mouse cells exposed to the metabolite alpha-ketoglutarate became more likely to renew themselves.
Bridging Quantitative Analysis and Untargeted Metabolomics
Untargeted metabolomics has become a popular tool in metabolite biomarker discovery and in the evaluation of metabolic pathway changes associated with disease.
Light-activated Drug Could Reduce Side Effects of Diabetes Medication
Scientists have created a drug for type 2 diabetes that is switched on by blue light, which they hope will improve treatment of the disease.
Getting Metabolism Right
Analysis of 89 models of metabolic processes finds flaws in 44 of them — but suggests corrections.
Biologists Find An Early Sign Of Cancer
Patients show boost in certain amino acids years before diagnosis of pancreatic cancer.

Predicting Clinical Resistance to Gleevec Treatment by in vitro Applied Stable Isotope-based Dynamic Metabolic Profiling
Laszlo G. Boros, Los Angeles Biomedical Research Institute at UCLA and SIDMAP, LLC, speaking at Advances in Metabolic Profiling 2005

Metabolic Profiles and Biomarkers for Detection and Prediction of Drug Effects
Hans Senn of F. Hoffmann-La Roche AG speaking at Advances in Metabolic Profiling 2005.

Predicting the Safety of FDA Regulated Products with Metabolomics
Laura Schnackenberg, Center for Metabolomics Research, speaks at Advances in Metabolic Profiling 2005.

The Application of Metabolic Profiling Techniques in Biomarker Discovery in Drug R&D
Dr. Ina Schuppe Koistinen, AstraZeneca R&D speaking at Advances in Metabolic Profiling 2005

Metabolomics as a Tool for Biomarker Discovery
Dr. Chris Beecher, Vice President of Biochemistry and Technology, Metabolon, Inc., speaking at Advances in Metabolic Profiling 2005

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