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Light-activated Drug Could Reduce Side Effects of Diabetes Medication
Scientists have created a drug for type 2 diabetes that is switched on by blue light, which they hope will improve treatment of the disease.
Getting Metabolism Right
Analysis of 89 models of metabolic processes finds flaws in 44 of them — but suggests corrections.
Biologists Find An Early Sign Of Cancer
Patients show boost in certain amino acids years before diagnosis of pancreatic cancer.
Comparison of Caffeinated and Decaffeinated Coffee - Implications for Alzheimer's Disease
Researchers from the National University of Singapore successfully demonstrated the viability of GC-TOF-MS as an analytical platform for metabolomics analysis of coffee samples.
Single Enzyme is Necessary for Development of Diabetes
12-LO enzyme promotes the obesity-induced oxidative stress in the pancreatic cells.
A New Player in Lipid Metabolism Discovered
Specially engineered mice gained no weight, and normal counterparts became obese on the same high-fat, obesity-inducing Western diet.
UT Southwestern Researchers Uncover New Brain Pathways
New therapies for treating Type 2 diabetes and obesity.
Mass Spec-Based Metabolomics Workflows to Evaluate Plant Immunity
This article reviews metabolomics studies used to evaluate plant immunity with an emphasis on mass spectrometry in its many forms.
Assessing Anticancer Drugs Efficacy by Amino Acid Metabolomics
Researchers aimed to develop a method that determines the therapeutic efficacy of anticancer drugs based on the changes in amino acid metabolism at the cellular level.
Time Of Day Crucial to Accurately Test for Diseases
A new study published in PNAS has found that time of day and sleep deprivation have a significant effect on our metabolism.
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Challenges in the Development of Tissue Biomarkers
Steven Hewitt, Chief, Tissue Array Research Program, National Cancer Institute, Maryland, speaking at Microarray World Congress 2009
Date Posted: Wednesday, December 02, 2009
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Antibodies Against Abnormal Glycoproteins Identified as Possible Biomarkers for Cancer Detection
Scientists have found that cancer patients produce antibodies that target abnormal glycoproteins made by their tumors.
Thursday, February 04, 2010
Gene Mutations Reveal Potential new Targets for Treating a Type of Non-Hodgkin's Lymphoma
Findings provide insight into a mechanism that cancer cells may use to survive.
Friday, January 08, 2010
New Biomarker Method Could Increase the Number of Diagnostic Tests for Cancer
Researchers develop a potential method to increase accuracy in detecting real cancer biomarkers that is highly reproducible across laboratories.
Friday, July 03, 2009
Researchers Identify a Novel Mechanism that could be Targeted to Prevent Cancer Spread
Researchers find that function of a specific protein helps control the levels of critical proteins that suppresses the spread of cancer.
Monday, June 29, 2009
Cancer Immunotherapy Can Use Small Numbers of Stem-Like Immune Cells to Destroy Large Tumors in Mice
New approach to stimulating immune cells enhances their anticancer activity, resulting in a powerful anti-tumor response in mice.
Friday, June 26, 2009
Genetic Variant Associated with Resistance to Chemotherapy Drug in Women with Breast Cancer
Findings show how a genetic variant may affect how a person responds to the chemotherapy drug cyclophosphamide.
Wednesday, June 10, 2009
New Early Detection Studies of Lung Cancer in Non-Smokers Launched
Government and private sector cancer scientists have launched a research partnership to find biomarkers for lung cancer that develops in people who have never smoked.
Wednesday, May 06, 2009
NIH Center for Interventional Oncology Offers new Venue for Research Collaborations
The new center offers new and expanded opportunities to investigate cancer therapies that use imaging technology to diagnose and treat localized cancers.
Thursday, April 30, 2009
Researchers Discover Potential Functional Role of Genetic Variation in Prostate Cancer Risk
The study uncovered how a small change in the DNA of the gene impacts the biology of prostate cancer risk.
Monday, April 27, 2009
Compound Can Distinguish Between Benign Tissue and Localized and Metastatic Prostate Cancer
Researchers have determined that a molecule produced by the body's metabolism could be used to differentiate between prostate cancers.
Thursday, February 12, 2009
New Tool Developed to Predict Colorectal Cancer Risk
A newly launched online tool for calculating colorectal cancer risk is based on a new risk-assessment model developed by researchers at NCI.
Thursday, January 01, 2009
New Targeted Fluorescent-Imaging Compound Allows Researchers to Detect Viable Cancer Cells in Mice
Researchers develop a new type of imaging compound to visualize viable breast cancer cells that have spread to the lungs in mice.
Tuesday, December 09, 2008
Variations in Gene Activity Can Predict the Survival of Patients with Lymphoma
Patterns of gene activity in a type of non-Hodgkin lymphoma has given researchers a better understanding of factors that contribute to the survival of patients treated for the disease.
Monday, December 01, 2008
NCI Launches First-Ever Study to Determine if Biomarkers Can Help Guide Treatment for Lung Cancer
The study, called MARVEL, will attempt to definitively establish the future value of selecting patients for treatment based on the presence or absence of EGFR activation.
Monday, October 06, 2008
Laboratory and Mouse Studies Show Targeted Drug Blocks the Growth of Breast Cancer Cells that Spread to the Brain
Researchers have found that a small molecule capable of targeting specific proteins on the surface of breast cancer cells can inhibit the growth of breast cancer cells that migrate to the brain.
Wednesday, July 30, 2008
 
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