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Webcasts
Characterising Plant Genomes The Good The Bad and The UglyCharacterising Plant Genomes The Good The Bad and The Ugly
Dave Edwards, University of Queensland, speaking at Advances in Plant Genomics 2014
Next Generation Genomics and Genetics for Accelerating Genetic Gain in Plant Breeding: Some Examples in Grain LegumesNext Generation Genomics and Genetics for Accelerating Genetic Gain in Plant Breeding: Some Examples in Grain Legumes
Rajeev Varshney, International Crops Research Institute for the Semi Arid Tropics, speaking at Advances in Plant Genomics

Market Reports
Gene Expression Analysis Market by Technology, Consumables, Services & Applications - Global Forecast to 2018
MarketsandMarkets

Over the years, the gene expression analysis market, comprising of instruments, consumables, and services, has witnessed various technological advancements. These advancements have led to a growth in the number of gene expression applications.
DNA Sequencing
RI Technologies

This report presents an in depth analysis of DNA sequencing market. The study emphasizes on both, the methods and instruments/software of DNA sequencing in medical research, agriculture and animal husbandry and DNA testing and forensics application areas.
Big Data Market in India 2013
Netscribes

The report highlights the current as well as the future big data market scenario in India. The report furnishes explicit details on the crucial aspects of the overall market to provide a holistic view, with the aide of crisp and insightful representation of market data.
Life Science Software 2013: Markets and Opportunities
Biopharm Reports

This reports into in the life science field examines the use of specialist software and databases relating to the conduct of PCR, DNA sequencing, DNA microarray, flow cytometry, mass spectrometry and disease biomarker studies. The studies were carried out to assist software developers and vendors to identify market opportunities in these fields.
DNA Sequencing 2013: Market Developments, Growth Areas and Opportunities
Biopharm Reports

DNA sequencing is important in all areas of biological research and increasing demand for this technique is driving advances in this field, in the form of next-generation techniques. Today, laboratories use a number of different sequencing methods, however common goals include increasing throughputs and speeds, while reducing costs.
Life Science Consumables 2013: Markets and Opportunities
Biopharm Reports

Techniques such as PCR, DNA microarray, DNA sequencing, mass spectrometry and flow cytometry have grown significantly in the last decade and by 2015 markets for these five areas are expected to exceed $50 billion, globally. In these and related fields, consumables are generally the second or third largest area in cost terms, after instrumentation.
Benchtop Automation Trends 2013
HTStec

This market report summarizes the results of HTStec's industry-wide global web-based benchmarking survey on small-scale or benchtop automation carried out in January 2013.
Next-Gen Sequencing Trends 2012
HTStec

This market report summarizes the results of HTStec’s 3rd industry-wide global web-based benchmarking survey on next-generation sequencing (NGS) carried out in November 2012.
High Throughput qPCR Assay Trends
HTStec

This market report summarizes the results of HTStec’s global web-based benchmarking survey on high throughput real-time quantitative PCR (HT qPCR) assays carried out in January 2012.
The Future of Molecular Diagnostics: Innovative technologies driving market opportunities in personalized medicine
Business Insights

This report analyzes the current and potential world markets for molecular diagnostics, including advances in the field. This report generally forecasts future growth to 2015. The report breaks down market forecasts by type of test and by geography. It indicates which companies have key products in the market place. It also analyzes key drivers of this market.
Scientific News
What Drives Advanced Prostate Cancer?
Large international study finds 90% have anomaly that could influence treatment.
Beyond Average
Researchers have created new platforms to genetically barcode tens of thousands of cells at a time allowing unprecedented detail to be uncovered when studying whole tissue samples.
‘Measuring Stick’ Standard for Gene Sequencing Now Available from NIST
New reference material, NIST RM 8398, to “map” DNA for genetic testing.
Single-cell Analysis Hits its Stride
Advances in technology and computational analysis enable scale and affordability, paving the way for translational studies.
Normal Skin Accrues High Number of Mutations Associated with Cancer
Researchers used genomic sequencing to gain insights into how somatic mutations build up in normal cells before the onset of cancer, a process that is poorly understood.
Diversity of the Global Ocean Microbiome
The Tara Oceans Consortium have revealed the huge diversity of species living in the oceans including viruses, prokaryotes and picoeurokaryotes.
Giant Panda Microbiome Poorly Adapted for a Bamboo Diet
Researchers have found that the microbiome of the Giant Panda lacks key bacterial species typically found in herbivores.
Study Looks at the Diagnostic Utility of Whole-Genome Sequencing
New research explores the potential of whole genome sequencing to revolutionize the diagnosis of genetic disorders in a clinical setting.
Using Microbial Communities to Assess Environmental Contamination
First there were canaries in coal mines, now there are microbes at nuclear waste sites, oil spills and other contaminated environments.
Potential Forensic Uses for Human Microbiome
A recent study suggests microbial communities found on or in some sites in an individual's body can be used as fingerprint-like identifiers.
Business News
Pacific Biosciences and RainDance Technologies Partner
Partnership combines Pacific Biosciences’ Single Molecule, Real-Time (SMRT®) Sequencing and informatics capabilities with RainDance’s proprietary digital droplet and single molecule barcoding technology.
Illumina Files New Patent Infringement Suit
Company has filed a new suit against Ariosa Diagnostics, Inc. and Roche Molecular Systems, Inc.
New Affordable Advanced NGS Cancer Test Launched by EKF subsidiary
Selah and GHS have partnered to produce an NGS technology, PrecisionPath, which will allow doctors to provide tailored cancer treatment based on a patients genes.
AstraZeneca and Montreal Heart Institute Partner
AstraZeneca and Montreal Heart Institute to screen 80,000 samples for cardiovascular and diabetes genetic traits.
GenomeDx Launches Genomics Data-Sharing Program
The company have launched a clinical genomics data-sharing program with the Sidney Kimmel Cancer Centerat Thomas Jefferson University as the first institutional partner.
Affymetrix Acquires Assets of Eureka Genomics
Aquisition will enable provision of high throughput and economical crop and animal genotyping.
SYGNIS Reports Financial Results for Fiscal Year 2014
Successful change in product and commercialization strategy with strong focus on proprietary product portfolio.
WaferGen & Genentech Collaborate
WaferGen’s SmartChipTM platform has potential to accelerate pharmaceutical drug discovery and development.
The Agrigenomics Market
Exponential population growth and changing climate patterns are creating unique challenges for the agriculture industry. To continue to address global food needs, many researchers, breeders, and farms are turning to genomics, or DNA science, to optimize production.
SYGNIS Signs Non-exclusive Distribution Agreement with Cambridge Bioscience
Significant expansion of product roll-out into one of the most important life science markets in Europe.

Events
International Conference on Ad
28 May 2015
International Conference on Ad ...
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3rd Annual Next Generation Seq
15 Jun 2015
3rd Annual Next Generation Seq ...
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Plant Genomics Congress USA
14 Sep 2015
Plant Genomics Congress USA ...
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Next Generation Sequencing, Si
28 Sep 2015
Next Generation Sequencing, Si ...
More Information

ePosters
Bovine RNA-seq data analysis of liver and pituitary gland
(1) Functional Genomics Lab. Faculty of Biology and Environmental Protection, Nicolaus Copernicus University, Torun, Poland, (2) Interdisciplinary Centre of Modern Technology, Nicolaus Copernicus Uni

Two key applications of RNA-seq i.e., i) transcriptome read mapping to a reference genome and ii) SNP detections were investigated to analysis of bovine liver and pituitary gland transcriptome. Here, we have presented ONLY the obtained results of bovine pituitary gland.
Improved Small RNA Library Preparation Workflow for Next-Generation Sequencing
TriLink BioTechnologies

We describe an optimized workflow which suppresses adapter dimers, works with low RNA input and eliminates the need for a gel purification step.
Whole Transcriptome RNA-SEQ with Ion Torrent Platform: FFPE, Fresh LCM and FFPE LCM Samples. Increasingly Difficult
1Pisa Science Founda:on, Pisa; Italy 2Department of Pathology, Pisa University Hospital, Pisa, Italy

We developed a high performance method to analyze the whole transcriptome of our FFPE samples, obtaining a very high number of reads (78,186,377 usable reads) perfectly comparable with samples with a large amount of RNA such as samples obtained from cells or fresh tissues.
Study Of The Active Bacterial Community In Two Membrane Bioreactors
1 Research Institute of Water and Environmental Ingeneering (IIAMA), Polytechnic University of Valencia 2 I+D+i Department , Urbaser S.A.

In this work, bacterial communities from two MBR systems treating leachates were evaluated using the 16S rRNA metagenomics approach, with and without a viability dye (Propidium Monoazide, PMA).
Innovative technology that enables RNAi in difficult to transfect cells
GE Healthcare Dharmacon, Inc.

Investigations at Dharmacon have led to the development of innovative siRNA molecules that can be delivered into difficult-to-transfect cells without additional lipid reagents, virus, or instruments. This technology, Accell siRNA reagents, enables gene knockdown for functional genomic studies in a wide variety of cell types. In some instances, cells can be continuously dosed with Accell siRNAs to enable target gene knockdown for extended durations.
LOHA Comprehensive Assay for Single Nucleotide Polymorphism, Copy Number Variants and Loss of Heterozygosity Using SureSelect Target Enrichment
Agilent Technologies, Diagnostics and Genomics Group

Here we describe a comprehensive assay that enables researchers to identify SNP, INDEL, CNV, and LOH using SureSelect target enrichment. This design can be employed as a standalone entity or in concert with other bait designs for SNP and INDEL detection. We also describe methods for data analysis and visualization.
Improved Small RNA Library Preparation Workflow for Next-Generation Sequencing
TriLink BioTechnologies

We describe an optimized small RNA NGS library prep workflow using chemically modified adapters which suppresses adapter dimers, allows for RNA inputs down to 1 ng and eliminates the need for a gel purification step, thus allowing full automation not previously possible.
Non-invasive Liquid Biopsy
1 Life Technologies AS, Ullerchausséen 52, 0379, Oslo, Norway; 2Department of Immunology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway; 3 Centre for Cancer Biomedicine, Univ

Paramagnetic Dynabeads® magnetic beads provide a versatile, automation friendly tool for fast sensitive and high throughput isolation that can be tailored to isolate specific circulating biomarkers such as cells, exosomes and nucleic acids.
A multiplexed amplicon sequencing technology for FFPE and circulating, cell-free DNA
Swift Biosceinces

A novel amplicon approach allowing for hundreds of amplicons to be multiplexed in a single tube with a two workflow from sample to sequencer.
Reducing Biases in Small RNA Sequencing
Bioo Scientific

Small RNA-Seq libraries utilizing randomized adapters demonstrated significantly less bias and more even coverage due to reductions in ligase bias.
Application Notes
Improved Library Prep Offers Higher Percentage of On-target Reads and Better Coverage for SureSelectXT2 Target Capture
Bioo Scientific

The seamless compatibility between the NEXTflex Pre- and Post- Capture library preparation kit and all reagents required for target capture using Agilent’s SureSelectXT2 bait set is demonstrated.
Directional qRNA-Seq: Combining the Power of Stranded RNA-Seq with the Quantitative Precision of Molecular Labels
Bioo Scientific

Bioo Scientific introduces a novel product for advanced RNA-Seq library preparation that features strand-specific RNA sequencing and correction of PCR amplification bias by molecular indexing: the NEXTflex™ Rapid Directional qRNA-Seq™ Kit.
Approaching Single-Cell Sequencing by Understanding NGS Library Complexity and Bias
Swift Biosciences Inc

This application note describes the sequence coverage performance andp reservation of molecular complexity of next generation sequencing (NGS) libraries generated from human and microbial genomic DNA using the Accel-NGS™ 2S DNA Library Kit for whole-genome sequencing (WGS) on the Illumina® platform.
Automated Illumina TruSeq® Nano DNA Sample Preparation
Tecan Group Ltd.

The TruSeq Nano DNA Sample Preparation Kit enables efficient investigation of samples where the amount of DNA available is limited. This low-input method generates excellent quality data from as little at 100 ng of DNA, allowing the study of samples with restricted DNA availability, for example from tumors, and helping to preserve precious sample material for use in future studies.
Double stranded DNA quantitation using Promega QuantiFluor® Dyes
Tecan Group Ltd.

Achieving selective and sensitive quantitation of double stranded DNA (dsDNA) using spectrophotometric methods can be problematic. Recognizing these difficulties, researchers have incorporated fluorescence-based quantitation techniques in their workflows to obtain the required sensitivity and target selectivity.
Automated Illumina NGS Sample Preparation: TruSeq® Stranded mRNA on the Hamilton Microlab STAR
Hamilton Robotics

Illumina’s sample preparation kits produce high quality libraries for DNA and RNA sequencing. Hamilton offers the robust Microlab STAR line of robotic liquid handling workstations for automating sample preparation. Together, the automation of the TruSeq Stranded mRNA sample preparation protocol on the STAR gives the user hours of reliable, unattended library preparation.
Molecular indexing for improved RNA-Seq analysis
Bioo Scientific

Most modern methods for nucleic acid analysis require the use of enzyme processing, such as DNA polymerase reactions, in the sample preparation or measurement steps. Although necessary, these enzymatic steps introduce errors in the form of incorrect sequence and misrepresented copy number. NEXTflex™ qRNA-Seq™ Kit from Bioo Scientific adds no additional steps to the work flow, costs no more than a conventional library preparation kit and increases the precision of downstream analysis.
An Integrated Solution to Simplify Library Preparation and Multiplexing for NimbleGen Sequence Capture
Bioo Scientific

The studies described herein demonstrate the capability of Bioo Scientific’s novel NEXTFlex™ DNA Pre-Capture Combo Library construction kits used in conjunction with the NimbleGen Sequence Capture technology to obtain high coverage comparative genomic data from a panel of human HapMap DNA samples.
Next Generation Sequencing Method for Illumina TruSeq DNA Sample Preparation Protocol on the Hamilton STAR
Hamilton

The purpose of the TruSeq sample preparation protocol is to add adapter sequences onto the ends of DNA fragments to generate multiplexed sequencing libraries. Good liquid handling is crucial for pipetting precise volumes for example for Agilent Bioanalyzer.
Tools for Enhancing Sequence Diversity and Reducing Bias in DNA-seq Library Preparation
Bioo Scientific

The generation of high quality next generation sequencing data begins with libraries that have the desired insert size and proper adapter ligation.
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