Chromatin immunoprecipitation and DNA methylation assays followed by next generation sequencing is a powerful technique for generating genome-wide profiles of epigenetic modifications and transcription factor binding sites. The SX-8G IP-Star® Compact Automated System provides the flexibility needed to change multiple parameters in the protocols to achieve optimal experimental conditions. Samples generated on the system are compatible with popular downstream applications such as QPCR, microarrays and next generation sequencing platforms. In addition to automated ChIP and DNA methylation protocols, this system contains a wide variety of protocols including next generation sequencing library preparation and sample purification.
Decoding the Genome of the Olive Tree A team of scientists from three Spanish centers has sequenced, for the first time ever, the complete genome of the olive tree. This work will facilitate genetic improvement for production of olives and olive oil, two key products in the Spanish economy and diet.Four Newly-Identified Genes Could Improve Rice A Japanese research team have applied a method used in human genetic analysis to rice and rapidly discovered four new genes that are potentially significant for agriculture. These findings could influence crop breeding and help combat food shortages caused by a growing population. What Makes a Good Scientist? It’s the journey, not just the destination that counts as a scientist when conducting research.Biomarkers That Could Help Give Cancer Patients Better Survival Estimates Discovered UCLA research may also help scientists suppress dangerous genetic sequences.Mobile Laboratories Help Track Zika Spread Across Brazil Researchers from the University of Birmingham are working with health partners in Brazil to combat the spread of Zika virus by deploying a pair of mobile DNA sequencing laboratories on a medical ‘road trip’ through the worst-hit areas of the country.How “Silent” Genetic Changes Drive Cancer The researchers found that EXOSC2 expression is enhanced in metastatic tumors because their cells have increased levels of a tRNA called GluUUC.‘Jumping Gene’ Took Peppered Moths To The Dark Side Researchers from the University of Liverpool have identified and dated the genetic mutation that gave rise to the black form of the peppered moth, which spread rapidly during Britain’s Industrial Revolution.Benchtop Automation Trends Gain a better understanding of current interest in and future deployment of benchtop automated systems.How Did The Giraffe Get Its Long Neck? Clues about the evolution of the giraffe’s long neck have now been revealed by new genome sequencing.Big Data Can Save Lives The sharing of genetic information from millions of cancer patients around the world could be key to revolutionising cancer prevention and care, according to a leading cancer expert from Queen's University Belfast.