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Decoding the Genome of the Olive Tree
A team of scientists from three Spanish centers has sequenced, for the first time ever, the complete genome of the olive tree. This work will facilitate genetic improvement for production of olives and olive oil, two key products in the Spanish economy and diet.
Four Newly-Identified Genes Could Improve Rice
A Japanese research team have applied a method used in human genetic analysis to rice and rapidly discovered four new genes that are potentially significant for agriculture. These findings could influence crop breeding and help combat food shortages caused by a growing population.
What Makes a Good Scientist?
It’s the journey, not just the destination that counts as a scientist when conducting research.
Biomarkers That Could Help Give Cancer Patients Better Survival Estimates Discovered
UCLA research may also help scientists suppress dangerous genetic sequences.
Mobile Laboratories Help Track Zika Spread Across Brazil
Researchers from the University of Birmingham are working with health partners in Brazil to combat the spread of Zika virus by deploying a pair of mobile DNA sequencing laboratories on a medical ‘road trip’ through the worst-hit areas of the country.
How “Silent” Genetic Changes Drive Cancer
The researchers found that EXOSC2 expression is enhanced in metastatic tumors because their cells have increased levels of a tRNA called GluUUC.
‘Jumping Gene’ Took Peppered Moths To The Dark Side
Researchers from the University of Liverpool have identified and dated the genetic mutation that gave rise to the black form of the peppered moth, which spread rapidly during Britain’s Industrial Revolution.
Benchtop Automation Trends
Gain a better understanding of current interest in and future deployment of benchtop automated systems.
How Did The Giraffe Get Its Long Neck?
Clues about the evolution of the giraffe’s long neck have now been revealed by new genome sequencing.
Big Data Can Save Lives
The sharing of genetic information from millions of cancer patients around the world could be key to revolutionising cancer prevention and care, according to a leading cancer expert from Queen's University Belfast.
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OmicSoft Aligner
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OmicSoft Corporation

Whitepaper discussing the technique of aligning next generation sequencing (HTS) data.

OSA is Omicsoft's read aligner designed for high performance alignment of short or long reads to reference libraries (genomes or transcriptomes).

 Key features of OSA:
1. High performance for both single end alignment and paired end alignment. Works on reads with 17-65536 nucleotides.
2. For Illumina reads (17nt or longer), allow any number of mismatches and a single indel in the reads. Can identify and report all available alignments in the genome with specified mismatches/indel.
3. For long reads (e.g. 454 reads or PacificBio reads), allow any number of mismatches and indels in the reads. Use banded Smith-Waterman to find the optimal alignment.
4. Directly align RNA-Seq reads to genome by considering both known and novel exon junctions
5. Directly align fusion reads: reads spliced by two different genes or genomic regions
6. Automatic quality based trimming
7. Automatic adapter trimming
8. Support all common input formats (.fasta; .fastq; .qseq; .sff); directly support .gzip files allowing savings in file space
9. Support multiple threads

Further Information


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