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Big Genetics in BC: The American Society for Human Genetics 2016 Meeting
Themes at this year's meeting ranged from the verification, validation, and sharing of data, to the translation of laboratory findings into actionable clinical results.
Accelerating the Detection of Foodborne Bacterial Outbreaks
The speed of diagnosis of foodborne bacterial outbreaks could be improved by a new technique developed by researchers at the Georgia Institute of Technology.
Antibiotics Discovered While Sifting Through Human Microbiome
Researchers identify genes in a microbe’s genome that produce antibiotic compounds, then synthesize them without the need for bacterial culture.
A Genome-wide View of Human DNA Viruses
In this study, Duplex sequencing was used to accurately analyse the genome-wide rate of spontaneous mutation of human adenovirus C5 (HAdv5).
Peer Review is in Crisis, But Should be Fixed, Not Abolished
After the time to get the science done, peer review has become the slowest step in the process of sharing studies, and some scientists have had enough.
Rare Immunodeficiency Yields Unexpected Insights
Scientists uncover previously unknown gene mutation revealing the role of a key molecule involved in immune cell development.
Cancer Genetics: Key to Diagnosis, Therapy
When applied judiciously, cancer genetics directs caregivers to the right drug at the right time, while sparing patients of unnecessary or harmful treatments.
Illumina Contributes to ClinVar Database
The contribution includes variants of all classifications, from pathogenic to benign, identified during interpretation of whole genome sequences generated in the CLIA-certified, CAP-accredited Illumina Clinical Services Laboratory.
Agilent Presents Early Career Professor Award to Dr. Roeland Verhaak
JAX professor recognized for the development and implementation of workflows for the analysis of big-data from transcriptomics to next generation sequencing approaches.
Integrated Omics Analysis
Studying multi-omics promises to give a more holistic picture of the organism and its place in its ecosystem, however despite the complexities involved those within the field are optimistic.
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Next-Generation Data Storage
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Quantum Corp.

The explosion in life sciences data in general, and next-generation sequencing in particular, is nothing short of remarkable. At the 2010 Bio-IT World Expo, the director of IT at a leading genome institute casually remarked that he had just ordered 1.1 petabytes of storage to try to cope with the extraordinary surge in data generation. This puts a premium on sophisticated IT solutions not only for storing data, with reliable and secure backup and retrieval systems. Organizing the data, much of which is generated and viewed once and once only, is a problem that will require more work in future. In this Briefing On supplement, we present a selection of stories published in the past 12-24 months that have examined the technologies that are both creating and solving the next-gen data deluge (“The DNA Data Deluge”).

Increasingly, the value of next-gen sequencing studies is being validated with the identification of rare disease genes in studies of small families (“Next- Generation Genome Sequencing Identifies Disease Genes”). It is possible that the arrival of third-generation sequencing solutions, such as that from Pacific Biosciences (“PacBio’s Eleven”), will reduce the intense need to store image data, but IT managers aren’t popping the champagne corks just yet. One of the most interesting trends in next-gen data management is the potential of “on demand”.

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