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  Events - November 2012


Clinical Trials in CNS

05 Nov 2012 - 06 Nov 2012 - London, UK



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The SMi Group is proud to present their 11th annual Clinical Trials in CNS conference that will discuss the latest developments in preclinical discovery, clinical trial design, clinical trial management and the latest developments in neurodegenerative treatments.

Key reasons to attend:

· Learn of the latest drug developments combating the key diseases in CNS, from Alzheimer's and dementia, to depression and schizophrenia 

· Discuss the cutting issues of the industry, from the ethics of outsourcing, to proving efficacy 

· Explore the latest innovations in pre-clinical discovery, trial optimisation and biomarker identification 

· Discover new ways to manage and adapt a clinical trial to ensure its success and efficiency  

· Network with key members of the industry involved in every part of clinical trials: from bench to   bedside 

Key Speakers Include:

· Johan Luthman, Senior Programme Leader, Merck & Co.

· Florian Von Raison, Global Program Head, Novartis

· Michael O’Neill, Senior Research Advisor, Eli Lilly

· Bruno Pitrosky, Global Program Lead, Primary Care, Pfizer PGRD

· Lars Bauer, Senior Medical Director, TA CNS, UCB Biosciences GmbH

· Frank Miller, Senior Statistician and Principal Scientist, AstraZeneca




Further information
Scientific News
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Study to Assess Shorter-Duration Antibiotics in Children
Physicians plan a clinical trial to evaluate whether short course anti-biotics are effective at treating CAP in children.
Cancer Gene Predicts Treatment Response in Leukaemia
Study indicates the patients suffering from a lethal for of acute myeloid leukemia may live longer when receiving milder chemotherapy drugs.
Injectable Biologic Therapy Reduces Triglycerides
Study finds first-of-its-kind therapy promising for patients with high triglycerides, cholesterol.
Testing Zika Vaccine in Humans Begins
The first of five planned clinical trials to test ZPIV vaccine in humans has begun.
Combination Therapy Improved Chemoresistance in Ovarian Cancer
The study demonstrates how an existing class of targeted therapies could be used to potentiate the tumor suppression induced by cisplatin.
Gene Therapy for Blistering Skin Disease Shows Promise
Grafting genetically altered skin onto patients’ chronic wounds marks the first time skin-based gene therapy has been demonstrated to be safe and effective in humans.
Alzheimer’s Treatment Moves a Step Closer
Merck scientists have reported the discovery of verubecestat, a structurally unique, orally bioavailable small molecule that has been shown to target the most visible sign of the disease in the brain.
Lynparza Phase III Progression-Free Survival Benefit
AstraZeneca announces results from Phase III SOLO-2 trial designed to determine the efficacy of Lynparza as a monotherapy for ovarian cancer.
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