Corporate Banner
Satellite Banner
Pharma Outsourcing
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Aesica Announces Collaboration with QRxPharma

Published: Tuesday, July 23, 2013
Last Updated: Tuesday, July 23, 2013
Bookmark and Share
Agreement for the worldwide promotion of Stealth Beadlets® abuse deterrence technology.

Aesica Pharmaceuticals has announced the signing of an agreement between its subsidiary, Aesica Formulation Development Ltd, and QRxPharma Limited, for the global promotion of QRxPharma’s proprietary Stealth Beadlets® abuse deterrence technology.

Aesica supplies pharmaceutical contract development and manufacturing services internationally and operates six manufacturing sites across the UK, Germany and Italy.

The company provides controlled drug services across the supply chain, for which abuse or diversion may occur, and is actively building relationships for supplying controlled drug APIs and finished dose products to market.

Under the non-exclusive Collaboration Agreement, Aesica will promote QRxPharma’s Stealth Beadlets technology for specific use in controlled drugs formulations.

The company will enter into fee-for-service contracts with customers for the development of the new Abuse Deterrent Formulations (ADF) of specific drugs, whilst QRxPharma will negotiate license terms directly with the Aesica clients concerned.

QRxPharma’s proprietary Stealth Beadlets abuse deterrence technology was developed for the MOXDUO® CR (controlled release) formulation for the treatment of chronic pain.

This programme is ready for Phase 2 studies and has already shown that Stealth Beadlets, incorporated into the Company’s delayed release technology, provide a potential once to twice-a-day formulation.

Work is underway to assure that this ADF technology fully conforms with FDA guidelines for the provision of abuse deterrence statements in product labelling.

Stealth Beadlets can be incorporated into almost any potentially abused drug (e.g. opioids, amphetamines, sedatives, etc.) that are sold in solid dosage forms (e.g. tablet, capsule, sachet). They provide significant resistance against the extraction of active ingredients if crushed, solubilized or heated.

Moreover, Stealth Beadlets have no effect on the active ingredient release profile and consist entirely of patient-safe, low cost, excipients that have GRAS (Generally Regarded As Safe) status with FDA.

Patent applications for the ADF technology are currently under review at the U.S. patent office, and, if granted, will provide for product exclusivity through to 2029.

Alan Raymond, Sales and Marketing Director at Aesica Pharmaceuticals commented: “Aesica is very pleased to have secured this contract with QRxPharma. Indeed, we are committed to providing our customers with the most advanced technologies available for best performance and, consequently, the provision of Stealth Beadlets abuse deterrence technology in formulation development is set to be a highly beneficial addition for our customers in the pharmaceutical and life science markets.”

He continued: “We look forward to making this innovative technology readily available to customers across our international network.”

Remarking on the collaboration, Dr. John Holaday, Managing Director and Chief Executive Officer at QRxPharma, said: “We are delighted to announce our collaboration with Aesica. Their extensive experience in formulation development and contract manufacturing, together with their established client base in the controlled drugs market, creates a wonderful opportunity for our companies to collaborate in the application of our proprietary abuse deterrence technology by third party pharma companies”.

He added: “A head-to-head comparison between Stealth Beadlets and a market leading abuse deterrent technology showed that Stealth Beadlets were more than twice as effective in reducing the percentage of oxycodone that could be extracted from a crushed controlled release tablet.”


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,500+ scientific posters on ePosters
  • More than 5,000+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Aesica Opens New Development Centre
Strategic relocation of development and clinical manufacturing services from Nottingham to Queenborough is now complete.
Thursday, January 21, 2016
Aesica Concentrates Investment in Lucrative German Formulations Business
Zwickau site introduces roller compaction unit for dry granulation production.
Saturday, July 12, 2014
Aesica and CMIC Sign Collaborative Agreement
Memorandum of Understanding between the two companies will identify reciprocal consultation and manufacturing opportunities for clients in Japan and Europe whilst enabling joint collaborative development in the US.
Thursday, October 17, 2013
Scientific News
Drug to Treat Alcohol Use Disorder Shows Promise Among Drinkers With High Stress
The findings suggest that potential future studies with drugs targeting vasopressin blockade should focus on populations of people with AUD who also report high levels of stress.
Scientists Find Lethal Vulnerability in Treatment-Resistant Lung Cancer
The study describes how the drug Selinexor killed lung cancer cells and shrank tumors in mice when used against cancers driven by the aggressive and difficult-to-treat KRAS cancer gene.
Advanced Lymphoma in Remission After T-Cell Therapy
63% of trial participants who recieved two-drug combination chemo plus intermediate dose of engineered T cells went into complete remission.
New Treatment for Immune Cancers
Clinical trial shows new drug holds promise for treating advanced mastocytosis.
Sickle Cell Gene Therapy Passes Test
Researchers found a precision-engineered gene therapy virus reduced sickle-induced red-cell damage in mice with sickle cell disease.
Opening Door to Oesophageal Cancer Targeted Treatments
Scientists have discovered that oesophageal cancer can be classified into three different subtypes.
Vitamin C May Boost Leukemia Treatment
Studies show that supplementing an epigenetic cancer drug with vitamin C enhanced the drug's effectiveness.
Inovio Launches Zika Vaccine Trial
Inovio launches Zika vaccine trial in midst of Puerto Rico epidemic to explore early signals of vaccine efficacy.
New Hope for Zika Treatment Found in Large-Scale Screen of Existing Drugs
Johns Hopkins researchers join collaborative group to screen 6,000 existing drugs in hopes of finding treatments for Zika Virus infection
FINCH Filgotinib Phase 3 Program Initiated
Galapagos NV reports the initiation of the FINCH global Phase 3 program in rheumatoid arthritis patient populations.
Scroll Up
Scroll Down
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,000+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!