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Clinical Evaluation of induced pluripotent stem cells (iPSc) to cure patients with Psoriasis Vulgaris. An Open Study.
Timothy S. Andersson, David K. Chin, Wendy H. Wong

To evaluate the clinical efficacy of iPSc directed to interfere T-cell activation to cure patients with psoriasis. Twenty subjects were enrolled. Each patient was administered iv with syngenic iPS. Those showing lower PASI score were considered cured. The study states that induced iPSCs are safe and impart significant clinical efficacy to cure patients with psoriasis.

Ethnicity and Help-seeking
Kyle L. Gravel¹, Christina J. Sun², Nana Sadamura¹, Erin Moniz¹

Ethnic minorities have traditionally underutilized mental health services. It has been proposed that both willingness to see a counselor and attitudes towards seeking psychological help may impact utilization of psychological services among ethnic minority populations. The aim of this study was to explore the relationship between willingness to see a counselor and attitudes toward seeking psychological help among college students.

Clinical Outcomes and Emerging Challenges after 5 years of ART in Khayelitsha, South Africa
Gilles Van Cutsem1, Katherine Hilderbrand1,2, David Coetzee2,3, Carol Cragg3, Eric Goemaere1 & Andrew Boulle2,3

One of the first primary care antiretroviral treatment programs in Africa shows good patient outcomes at 5 years. Saturation of services has led to increased losses to follow-up.

Panic attack and suicide risk: A multivariate logistic regression analysis of a national epidemiological survey
Curren Katz, Ramin Mojtabai, Leo Bierman, Kathleen Camacho, Janine Samuel, Gillian Jennings, Igor Galynker

To examine the relationship between panic attack and suicide risk, we analyzed data from a representative epidemiological survey of 43,093 adults (NESARC) using logistic regression controlling for socio-demographic and clinical variables. In depression, panic attacks are associated with increased odds of suicide attempt even after controlling for demographic and clinical variables. Furthermore, panic attacks can differentiate those who attempt suicide from those with ideation only.

Panic attack and suicide risk: A multivariate logistic regression analysis of a national epidemiological survey
Curren Katz, Ramin Mojtabai, Leo Bierman, Kathleen Camacho, Janine Samuel, Gillian Jennings, Igor Galynker

To examine the relationship between panic attack and suicide risk, we analyzed data from a representative epidemiological survey of 43,093 adults (NESARC) using logistic regression controlling for socio-demographic and clinical variables. In depression, panic attacks are associated with increased odds of suicide attempt even after controlling for demographic and clinical variables. Furthermore, panic attacks can differentiate those who attempt suicide from those with ideation only.

What reduces ambulatory sensitive hospitalisation?
Arindam Basu and David Brinson

This poster showcases our review of interventions that were found to be effective in reducing ambulatory sensitive hospitalisations (ASH). ASH refers to those conditions where hospitalisations an be avoided by measures taken by clinicians and other carers at outpatient departments or in the community.

SYBR® Green I as a biomarker for schizophrenia
Davood Zaeifi, Mehdi Rahmati, Vahab Piranfar

The purpose of this study were to examine if the mRNA of the peripheral dopamine receptor is changed in schizophrenia patients. 50 Naive patients were enrolled. After extracting RNA from white blood cells, cDNA is synthesized. After doing the quantitative Real-time PCR, expression of D3 receptors in healthy persons and patients were compared. Results of this examinations reveals that expression of D3 receptor is increased in compared with controls sample.

What reduces ambulatory sensitive hospitalisation?
Arindam Basu and David Brinson

This poster showcases our review of interventions that were found to be effective in reducing ambulatory sensitive hospitalisations (ASH). ASH refers to those conditions where hospitalisations an be avoided by measures taken by clinicians and other carers at outpatient departments or in the community.

T cell response to cholera infection
Weil AA, Arifuzzaman M, Bhuiyan TR, Harris JB, Kendall EA, Hossain A, LaRocque RC, Harris AM, Tarique AA, Chowdhury F, Khan AI, Banerjee KK, Ryan ET, Qadri F, Calderwood SB

Natural Vibrio cholerae infection generates a robust B-cell response that wanes for T-cell independent antigens, suggesting that B-cell responses may be mediated in a T-cell dependent manner. Patients with cholera develop a memory-effector T-cell response to cholera antigens, and B-cell activation occurs after T-cell population expansion, suggesting that T-cells may play an important role in the development and maintenance of memory B-cell responses to T-cell dependent antigens.

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Showing Results 31 - 40 of 53
Scientific News
Advanced Lymphoma in Remission After T-Cell Therapy
63% of trial participants who recieved two-drug combination chemo plus intermediate dose of engineered T cells went into complete remission.
New Treatment for Immune Cancers
Clinical trial shows new drug holds promise for treating advanced mastocytosis.
Sickle Cell Gene Therapy Passes Test
Researchers found a precision-engineered gene therapy virus reduced sickle-induced red-cell damage in mice with sickle cell disease.
Opening Door to Oesophageal Cancer Targeted Treatments
Scientists have discovered that oesophageal cancer can be classified into three different subtypes.
Vitamin C May Boost Leukemia Treatment
Studies show that supplementing an epigenetic cancer drug with vitamin C enhanced the drug's effectiveness.
Inovio Launches Zika Vaccine Trial
Inovio launches Zika vaccine trial in midst of Puerto Rico epidemic to explore early signals of vaccine efficacy.
New Hope for Zika Treatment Found in Large-Scale Screen of Existing Drugs
Johns Hopkins researchers join collaborative group to screen 6,000 existing drugs in hopes of finding treatments for Zika Virus infection
FINCH Filgotinib Phase 3 Program Initiated
Galapagos NV reports the initiation of the FINCH global Phase 3 program in rheumatoid arthritis patient populations.
Stem Cell Therapy Heals Injured Mouse Brain
A team of researchers has developed a therapeutic technique that dramatically increases the production of nerve cells in mice with stroke-induced brain damage.
Zika Vaccine Testing in Humans
The NAAID has initiated a clinical trail of a vaccine candidate for the prevention of the Zika virus infection.
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