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Lucentis Effective for Proliferative Diabetic Retinopathy
NIH-funded clinical trial marks first major advance in therapy in 40 years.
Blocking the Transmission Of Malaria Parasites
Vaccine candidate administered for the first time in humans in a phase I clinical trial led by Oxford University’s Jenner Institute, with partners Imaxio and GSK.
First Therapy Appearing to Reverse Decline in Parkinson’s
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Gene Therapy Staves Off Blindness from Retinitis Pigmentosa in Canine Model
NIH-funded study suggests therapeutic window may extend to later-stage disease.
Treatment for Rare Bleeding Disorder is Effective
Researchers in Manchester have demonstrated for the first time the relative safety and effectiveness of treatment, eltrombopag, in children with persistent or chronic immune thrombocytopenia (ITP), as part of an international duo of studies.
HIV Vaccine Human Trials Begin
Baltimore-based Institute has begun enrolling volunteers for initial phase 1 clinical trials.
New Therapy Reduces Symptoms of Inherited Enzyme Deficiency
A phase three clinical trial of a new enzyme replacement medication, sebelipase alfa, showed a reduction in multiple disease-related symptoms in children and adults with lysosomal acid lipase deficiency, an inherited enzyme deficiency that can result in scarring of the liver and high cholesterol.
Fixing Holes in the Heart Without Invasive Surgery
UV-light enabled catheter is a medical device which represents a major shift in how cardiac defects are repaired.
Atriva Therapeutics GmbH Develops Innovative Flu Drug
Highly effective against seasonal and pandemic influenza.
Study Removes Cancer Doubt for Multiple Sclerosis Drug
Researchers from Queen Mary University of London are calling on the medical community to reconsider developing a known drug to treat people with relapsing Multiple sclerosis after new evidence shows it does not increase the risk of cancer as previously thought.
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Rising R&D costs, increasing expectations in the areas of productivity and quality, and a growing need to establish operations in close proximity to emerging markets are driving the international expansion of drug-discovery organizations. This global shift is driving new trends in the area of career development and hiring, such as the need for experienced scientific professionals at different locations all over the globe. Although the global pharmaceutical industry is going through significant changes, the role of medicinal chemistry in identifying and optimizing potential new drug candidates remains substantial. Going forward, current and future candidates in the area of medicinal chemistry and other scientific disciplines who have a willingness to work overseas may gain a competitive advantage when entering or advancing within the drug discovery field. 

During the past 10 years, there has been limited growth in the number of approved new chemical entities entering the marketplace in spite of a significant increase in overall R&D spending. For a number of reasons, R&D activities have also become more global during this time. As a result of this globalization associated with expanding international operations, there is an increased need for talent – principally with discovery and development skill sets – that may favor candidates who are willing to consider working in these non-traditional locations. 

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