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Salford Lung Study - The First Real World Clinical Trial
In this podcast, we learn about the Salford Lung Study and its potential to revolutionize the way we assess new drugs and treatments around the world.
NIH Contributes to Global Effort to Prevent and Manage Lung Diseases
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Anti-Inflammatory Drugs Could Help Treat Depression
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Questioning the Safety of Selenium to Combat Cancer
Research indicates the need for change in practice as selenium supplements cannot be recommended for preventing colorectal cancer.
Scientists at NIH and Emory Achieve Sustained SIV Remission in Monkeys
The finding suggest that the immune systems of these animals are controlling SIV replication in the absence of antiretroviral therapy.
Painting the Way to Tumour Imaging
Tumour paint used in emergency surgery to aid cell identification for surgeons.
Anti-Cancer Drug Uses Tumour mRNA to Identify Responders
Phase I study of novel anti-cancer drug uses tumour mRNA expression to identify patients who will respond to the drug.
Targeting Estrogen Receptor Improves Survival in Breast Cancer
Trial finds estrogen receptor degrader significantly increases progression-free survival in patients with advanced breast cancer.
Clinical Trial Finds Medicine Program Alters Blood Serum
Meditation, yoga and vegetarian diet linked to decline in plasma metabolites associated with inflammation and cardiovascular disease risk.
Alzheimer’s Linked Protein Can Be Removed From Brain Without Hindering Memory, Learning
Researchers at UTSW have found that the mice can maintain their learning and memory when virtually all ApoE is removed from the brain but kept present in the liver to filter cholesterol.
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Rising R&D costs, increasing expectations in the areas of productivity and quality, and a growing need to establish operations in close proximity to emerging markets are driving the international expansion of drug-discovery organizations. This global shift is driving new trends in the area of career development and hiring, such as the need for experienced scientific professionals at different locations all over the globe. Although the global pharmaceutical industry is going through significant changes, the role of medicinal chemistry in identifying and optimizing potential new drug candidates remains substantial. Going forward, current and future candidates in the area of medicinal chemistry and other scientific disciplines who have a willingness to work overseas may gain a competitive advantage when entering or advancing within the drug discovery field. 

During the past 10 years, there has been limited growth in the number of approved new chemical entities entering the marketplace in spite of a significant increase in overall R&D spending. For a number of reasons, R&D activities have also become more global during this time. As a result of this globalization associated with expanding international operations, there is an increased need for talent – principally with discovery and development skill sets – that may favor candidates who are willing to consider working in these non-traditional locations. 

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