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Saturday, November 29, 2014
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Scientific News
Two Drugs are No More Effective Than One to Treat Common Kidney Disease
NIH study finds limited kidney benefit from more rigorous blood pressure treatment.
Gene Therapy Provides Safe, Long-Term Relief for Patients with Severe Hemophilia B
Gene therapy pioneered by St. Jude Children’s Research Hospital, University College London and the Royal Free Hospital provides men with hemophilia B reliable relief from the bleeding disorder.
Themis Bioscience’s Vaccine Against Chikungunya Successful in Phase 1
Results presented at international conferences in Philadelphia and New Orleans.
Anti-Leukemia Drug May Also Work Against Ovarian Cancer
An antibody therapy already in clinical trials to treat chronic lymphocytic leukemia (CLL) may also prove effective against ovarian cancer – and likely other cancers as well.
Novel Cancer Vaccine Approach for Brain Tumors
Researchers unravel the mechanisms behind a novel cancer vaccine for brain tumors, paving the way for further development.
Almac Announces Launch of CLIA Validated Next Generation Sequencing Assay
P53 considered important biomarker for cancer drug discovery.
Classification of Gene Mutations in Neuroblastoma
Penn Medicine and CHOP experts define riskier mutations in neuroblastoma, setting stage for clinical trial.
New Vaccine Generates Strong Immune Response Against Hepatitis C
A new hepatitis C vaccine has shown promising results in an early clinical trial at Oxford University, generating strong and broad immune responses against the virus causing the disease.
Immune Booster Helps Improve Survival In Metastatic Melanoma
Patients with metastatic melanoma who were treated with ipilimumab, an immune checkpoint blocker, survived 50 percent longer – a median 17.5 months vs. 12.7 months – if they simultaneously received an immune stimulant.
Protecting us from Our Cells
Growth factor boosts natural defence against auto-immune disorders.
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Drug Discovery Outsourcing: the Importance of Integration in the Selection of Higher Quality Clinical Candidates
Simone Braggio, Director, Head of Drug Metabolism & Pharmacokinetics, Aptuit speaking at Pharma Outsourcing Congress 2011

RNA-Seq for High Throughput Clinical Studies
Wenzhong Xiao, Assistant Professor of Bioinformatics, Massachusetts General Hospital, speaking at Next-Gen Sequencing Congress 2011.

Preclinical Drug Safety: High Quality Data obtained with a New Automated Patch Clamp Platform
Olaf Scheel, CSO, Cytocentrics AG speaking at Pharma Outsourcing Congress 2011

Discovery Chemistry Outsourcing: Optimising the Process
Luigi LaVecchia, Director, Global Discovery Chemistry, Novartis speaking at Pharma Outsourcing Congress 2011

In a Virtual World, Where Are the Walls of the House?  The New Outsourcing
Katya Tsaioun, President, Apredica speaking at Pharma Outsourcing Congress 2011

Clinical Trials Utilising Radioactivity in Support of Drug Development
Stephen Madden, Head, Metabolism and Pharmacokinetics, Charles River speaking at ADMET Europe 2011

Selecting the right CMO partner
David Downey, VP, Commercial Operations, Almac Group speaking at Pharma Outsourcing Congress 2011

How to Obtain a Solid Track Record in Medicinal Chemistry Research Services
Bruno Giethlen, Chief Scientific Officer, Prestwick Chemicals speaking at Pharma Outsourcing Congress 2011

Biomarkers of Metabolic Syndrome in Clinical Trials
This will discuss the latest developments in biomarkers for metabolic syndrome. The topics will include: 1) Pre-analytical and analytical concerns regarding gut and incretin hormones, 2) dysfunctional HDL biomarkers in metabolic syndrome, and 3) kidney injury markers and their usefulness in diabetic nephropathy.

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