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Thursday, June 20, 2013
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Scientific News
Big Multiple Sclerosis Breakthrough
Phase 1 trial safely resets patients’ immune systems, reduces attack on myelin protein.
Combined Immunotherapy Shows Promising Results Against Advanced Melanoma
Combining two cancer immunotherapy drugs in patients with advanced melanoma produced rates of tumor regression that appeared greater than in prior trials with either drug alone.
NIH to Fund Clinical Research Network on Antibacterial Resistance
Researchers at Duke University will lead the initiative.
Combined Immunotherapy Shows Promising Results Against Advanced Melanoma
Tumor regression rates are produced by combining two cancer immunotherapy drugs.
Promising Drug Prevents Cancer Cells from Shutting Down Immune System
Data from Phase 1 trial presented at the 2013 annual meeting of the ASCO in Chicago.
Double Dose of Tamiflu Offers No Added Benefit in Severe Flu
Early treatment with Tamiflu is beneficial for patients with uncomplicated flu infection.
Enzyme-Activating Antibodies Revealed As Marker for Severe Rheumatoid Arthritis
Finding could lead to earlier diagnosis and new, more aggressive treatment for worst cases.
Researchers Identify Novel Class of Drugs for Prostate Cancers
A new study on prostate cancer describes a novel class of drugs that interrupts critical signaling needed for prostate cancer cells to grow.
Icahn School of Medicine at Mount Sinai and Rensselaer Polytechnic Institute Collaborate
Partnership will accelerate the pace of discovery and innovation in Biomedical Sciences.
First Patient Dosed in the Phase I/II Study of UC1010 for PMDD Patients
First patient has been dosed with UC1010 in a double-blind, multicenter study.
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Companies in Translation with CIRM
Dr Alan Trounson, California Institute for Regenerative Medicine, speaking at Stem Cells 2012

Drug Discovery Outsourcing: the Importance of Integration in the Selection of Higher Quality Clinical Candidates
Simone Braggio, Director, Head of Drug Metabolism & Pharmacokinetics, Aptuit speaking at Pharma Outsourcing Congress 2011

RNA-Seq for High Throughput Clinical Studies
Wenzhong Xiao, Assistant Professor of Bioinformatics, Massachusetts General Hospital, speaking at Next-Gen Sequencing Congress 2011.

Preclinical Drug Safety: High Quality Data obtained with a New Automated Patch Clamp Platform
Olaf Scheel, CSO, Cytocentrics AG speaking at Pharma Outsourcing Congress 2011

Discovery Chemistry Outsourcing: Optimising the Process
Luigi LaVecchia, Director, Global Discovery Chemistry, Novartis speaking at Pharma Outsourcing Congress 2011

In a Virtual World, Where Are the Walls of the House?  The New Outsourcing
Katya Tsaioun, President, Apredica speaking at Pharma Outsourcing Congress 2011

Clinical Trials Utilising Radioactivity in Support of Drug Development
Stephen Madden, Head, Metabolism and Pharmacokinetics, Charles River speaking at ADMET Europe 2011

Selecting the right CMO partner
David Downey, VP, Commercial Operations, Almac Group speaking at Pharma Outsourcing Congress 2011

How to Obtain a Solid Track Record in Medicinal Chemistry Research Services
Bruno Giethlen, Chief Scientific Officer, Prestwick Chemicals speaking at Pharma Outsourcing Congress 2011

Biomarkers of Metabolic Syndrome in Clinical Trials
This will discuss the latest developments in biomarkers for metabolic syndrome. The topics will include: 1) Pre-analytical and analytical concerns regarding gut and incretin hormones, 2) dysfunctional HDL biomarkers in metabolic syndrome, and 3) kidney injury markers and their usefulness in diabetic nephropathy.

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