Corporate Banner
Satellite Banner
Chemical Process Scale Up
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Free Webinar Explores Safe Scaling of Pressure Reactions

Published: Friday, May 24, 2013
Last Updated: Friday, May 24, 2013
Bookmark and Share
Robust in situ technology allows cost effective scale-up pressure reactions.

Mettler Toledo has presented the next installment in its thought-leading, on-demand webinar series. Entitled “Characterize, Optimize and Scale-up Pressure Reactions - Challenges and Solutions” and presented by Mettler Toledo Market Manager Brian Wittkamp, PhD, the free presentation reviews critical pressure-reaction design parameters.

It also explores enabling technologies such as Fourier Transform Infrared technology (FTIR) that help chemists gain better reaction control and more valuable reaction information for easier, safer and more cost-effective scale-up.

Although the objectives of chemical development have not changed in recent years, Dr. Wittkamp notes that the market has.

Chemists must bring new products to market faster, necessitating quick identification of workable opportunities and even quicker rejection of untenable ones.

FTIR instruments (ReactIR) helps deliver a process that is safe, economically viable and robust by providing critical understanding at small scale where lab resources, including development time, can be limited.

The data collected then allows these findings to be applied at larger scales.

Using a Mettler Toledo Easy Max synthesis workstation combined with Mettler Toledo ReactIR technology, two pressurized hydrogenation reactions are analyzed.

In the first, a one-step hydrogenation of a substitute 2-cyclohexene-1-one, mix rates are shown to influence reaction times. In the second, a complex hydrogenation of substituted hydrobenzene, accumulation of unstable hydroxylamine intermediate is prevented.

In each case, in situ FTIR data provides higher-value reaction chemistry information when compared with potentially time-consuming and error-prone offline sampling techniques.

Precise FTIR monitoring of critical parameters is shown to enhance researchers’ understanding and enable faster, safer optimization.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,900+ scientific posters on ePosters
  • More than 4,200+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Lab Scale Manufacturing Using Continuous Crystallization
A new METTLER TOLEDO On-demand webinar explores recent research that could revolutionize pharmaceutical production.
Tuesday, April 15, 2014
Mettler-Toledo Awarded Foreign Designated Manufacturer Certification
Mettler Toledo is the first balance manufacturer to win FDM certification in Japan.
Friday, July 26, 2013
Scientific News
Tiny 'Flasks' Speed Up Chemical Reactions
Self-assembling nanosphere clusters may improve everything from drug synthesis to drug delivery.
The Manufacturing Challenges of Nanotechnology
Head of NanoManufacturing at the Department of Engineering’s Institute for Manufacturing (IfM) Dr Michaël de Volder explains why manufacturing carbon nanotubes is so difficult – and so important.
New Material Lays Waste to Mercury Pollution
A brand new, dirt cheap, non-toxic polymer that literally sucks mercury out of water and soil is set to become a game changer in the battle against one of the world’s most reviled pollutants.
Shocking New Way to Get the Salt Out
MIT team invents efficient shockwave-based process for desalination of water.
Chemical Design Made Easier
Rice University scientists prepare elusive organocatalysts for drug and fine chemical synthesis.
2015 ACS GCI Pharmaceutical Roundtable Research Grant
Request for proposals: Greener Continuous Chemistry & Engineering Technology.
'Crumpled' Filter to Slash Energy Consumption
Scientists have developed an ultra-thin, super-strong membrane to filter liquids and gases, with the potential to cut energy consumption in industry.
Tackling Chemical Safety Rules and Regulations
Helsinki Chemicals Forum continues to lead international chemicals safety and management discussions.
Pioneering New Method to Map Enzyme Activity
Cardiff University researchers new discovery could have wide-reaching implications for the creation of manufactured goods, biofuels and therapeutic drugs.
Euro Vision turns Reality for Australia’s Iconic ‘Green Whistle’
Patients will soon benefit from a unique invention, with emergency pain killer Penthrox receiving initial regulatory approval for sale in the European and UK markets.
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,200+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!