Bringing Photochemistry to the Bench with Vapourtec Innovation
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Vapourtec (Suffolk, UK) has launched the easy-Photochem, a comprehensive, yet easy-to-use, system that aims to bring photochemistry to the bench chemist.
Photochemistry is a powerful yet under-utilized synthetic technique.
Recently there has been a resurgence in interest in photochemistry due to its ability to provide novel structures and alternative, greener synthetic routes. In developing the easy-Photochem, Vapourtec's aim is to bring photochemistry out of the hands of dedicated expert users and make the technique easily and safely available for general bench chemists.
Key features of the easy-Photochem include a high intensity medium pressure mercury lamp that can be controlled between 75 and 150 watts and a range of band-pass and long-pass filters that allow a desired range of wavelengths to be selected. In addition, narrow-band LED light sources are available for specific wavelengths in the range 365 nm to 500 nm.
It also delivers reaction temperature control between -5°C and 80°C, easily changed reactors, rugged self-priming pumps capable of metering gases, reaction pressures up to 10 bar and a touch-panel interface.
Vapourtec MD Duncan Guthrie explained: "Photochemistry is an under-utilized technique within medicinal chemistry with traditional batch photochemistry apparatus having their limitations.
"Continuous flow photochemistry has a number of significant advantages.
Firstly reaction products leave the reactor after exposure to the UV source delivering a cleaner reaction.
"Unstable intermediates resulting from reactions with photons can be immediately fed into a second reaction stage.
"In addition UV exposure times are precisely controlled and consistent and the UV penetration depth is not an issue as the thickness of the irradiated fluid is often less than 1.5mm.
"Continuous flow photochemical reactors are much smaller than their batch counterparts so the hazard of maintaining a large volume of solvent in close proximity to a discharge lamp is significantly reduced.
"Finally the photochemical reaction can be scaled simply by running the process for longer. Taken together, these benefits make the easy-Photochem a safe, easy-to-use, compact and affordable package," added Duncan.
