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Imperial College Employs Parallel Synthesis to Develop Better Catalysts
Asynt DrySyn MULTI and parallel synthesis kits to provide safer, more convenient way to perform heated catalytic reactions in parallel. Antimalarial Drug Launched Twelve years after a breakthrough discovery in his UC Berkeley laboratory, professor of chemical engineering Jay Keasling is seeing his dream come true. From Bead to Flask: Synthesis of a Complex ß-amido-amide for Probe-Development Studies This study reports the synthesis of LLW62, which is a complex benzimidazole-substituted ß-amido-amide similar in structure to inhibitors of p21 that were reported previously to support studies of this compound as a biological probe. Simultaneous Saccharification and Co-Fermentation for Bioethanol Production at Lab, PDU and Demo Scales In this study, researchers designed a SSCF process and scaled up from lab to demo scale reaching 4% (w/v) ethanol using xylose rich corncobs. Mechanochemistry Assisted Asymmetric Organocatalysis: A Sustainable Approach This review highlights the progress in asymmetric organocatalytic reactions assisted by mechanochemical techniques. Flow Photochemistry: Old Light Through New Windows This review highlights the use of flow reactors in organic photochemistry, allowing a comparison of the various reactor types to be made. Heterogeneously Catalyzed Continuous-Flow Hydrogenation Using Segmented Flow in Capillary Columns Researchers have utilized wall-catalyzed segmented flow to overcome monitoring and yield problems. Ask the Experts: The Challenges and Benefits of Flow Chemistry to Optimize Drug Development In this article a variety of experts from within Medicinal Chemistry discuss key issues concerning the use of flow chemistry to optimize drug development. A Quantitative Approach to Nucleophilic Organocatalysis In this review article researchers demonstrate that important information can be obtained by specifically synthesizing relevant intermediates and studying the kinetics of their reactions with nucleophiles or electrophiles. N-Heterocyclic Carbene/Brønsted Acid Cooperative Catalysis as a Powerful Tool in Organic Synthesis Cooperative catalysis is a powerful technique for the highly selective synthesis of a variety of target structures, in this commentary the concept of N-heterocyclic carbene/Brønsted acid cooperative catalysis will be highlighted. 
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