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Continuous-Flow Catalytic Asymmetric Hydrogenations: Reaction Optimization Using FTIR Inline Analysis
Researchers from RWTH Aachen University have coupled a ReactIR flow cell with the microreactor and applied as an inline monitoring device for optimizing the reactions.

Continuous-Flow Hydration-Condensation Reaction
Researchers from Aachen University report the synthesis of a,ß-unsaturated ketones from alkynes and aldehydes by using a heterogeneous solid acid catalyst.

Application of Modeling to Scale-Up Dissolution in Pharmaceutical Manufacturing
This article attempts to provide a model-based approach to scale-up dissolution process from a 2 l lab-scale vessel to a 4,000 l scale vessel used in manufacturing.

Continuous Preparation of Carbon-Nanotube-Supported Platinum Catalysts in a Flow Reactor Directly Heated by Electric Current
Researchers from Clausthal University of Technology present a continuous process for the production of highly active Pt catalysts supported by carbon nanotubes by use of an electrically heated tubular reactor.

Multistep Flow Synthesis of Vinyl Azides and their use in the Copper-Catalyzed Huisgen-type Cycloaddition under Inductive-Heating Conditions
In this article, researchers from Leibniz University Hannover report the multistep flow synthesis of vinyl azides and their application in the synthesis of vinyltriazoles.

Efficient and Selective Chemical Transformations under Flow Conditions: The Combination of Supported Catalysts and Supercritical Fluids
This paper reviews the current trends in the combined use of supported catalytic systems, either on solid supports or in liquid phases and supercritical fluids.

The Eschenmoser Coupling Reaction under Continuous-Flow Conditions
In this paper, researchers from Technische Universität Ilmenau investigate the reaction kinetics of the Eschenmoser coupling reaction.

Scaling up of Continuous-Flow, Microwave-Assisted, Organic Reactions by Varying the Size of Pd-Functionalized Catalytic Monoliths
Changing the volumetric capacity of the monolith under optimal reaction conditions was shown to increase the quantity of product from 31 mg per hour to 340 mg per hour.

Evaluation of a Commercial Packed Bed Flow Hydrogenator for Reaction Screening, Optimization and Synthesis
Scientists from Amgen have evaluated the performance of the ThalesNano H-Cube(®)in the context of small scale reaction screening and optimization.

Homocoupling of Aryl Halides in Flow: Space Integration of Lithiation and FeCl3 Promoted Homocoupling
Integration of the generation of aryllithiums by halogen–lithium exchange and FeCl3 promoted homocoupling has been effectively accomplished in an integrated flow microreactor system.