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Scientific News
Imperial College Employs Parallel Synthesis to Develop Better Catalysts
Asynt DrySyn MULTI and parallel synthesis kits to provide safer, more convenient way to perform heated catalytic reactions in parallel.
Antimalarial Drug Launched
Twelve years after a breakthrough discovery in his UC Berkeley laboratory, professor of chemical engineering Jay Keasling is seeing his dream come true.
From Bead to Flask: Synthesis of a Complex ß-amido-amide for Probe-Development Studies
This study reports the synthesis of LLW62, which is a complex benzimidazole-substituted ß-amido-amide similar in structure to inhibitors of p21 that were reported previously to support studies of this compound as a biological probe.
Simultaneous Saccharification and Co-Fermentation for Bioethanol Production at Lab, PDU and Demo Scales
In this study, researchers designed a SSCF process and scaled up from lab to demo scale reaching 4% (w/v) ethanol using xylose rich corncobs.
Mechanochemistry Assisted Asymmetric Organocatalysis: A Sustainable Approach
This review highlights the progress in asymmetric organocatalytic reactions assisted by mechanochemical techniques.
Flow Photochemistry: Old Light Through New Windows
This review highlights the use of flow reactors in organic photochemistry, allowing a comparison of the various reactor types to be made.
Heterogeneously Catalyzed Continuous-Flow Hydrogenation Using Segmented Flow in Capillary Columns
Researchers have utilized wall-catalyzed segmented flow to overcome monitoring and yield problems.
Ask the Experts: The Challenges and Benefits of Flow Chemistry to Optimize Drug Development
In this article a variety of experts from within Medicinal Chemistry discuss key issues concerning the use of flow chemistry to optimize drug development.
A Quantitative Approach to Nucleophilic Organocatalysis
In this review article researchers demonstrate that important information can be obtained by specifically synthesizing relevant intermediates and studying the kinetics of their reactions with nucleophiles or electrophiles.
N-Heterocyclic Carbene/Brønsted Acid Cooperative Catalysis as a Powerful Tool in Organic Synthesis
Cooperative catalysis is a powerful technique for the highly selective synthesis of a variety of target structures, in this commentary the concept of N-heterocyclic carbene/Brønsted acid cooperative catalysis will be highlighted.

Continuous Flow Multi-Step Organic Synthesis - Methods and Applications
Tim Jamison, Professor at Massachusetts Institute of Technology, speaking at Flow Chemistry Congress 2012.

Improving Organic Synthesis by Exploiting Flow Reactor
Professor Paul Watts, The University of Hull, speaking at Flow Chemistry Congress 2012.

Strategic Applications of Flow Chemistry within Drug Discovery
Paul Richardson, Synthesis Group Leader, Pfizer, speaking at Flow Chemistry Congress 2012.

Outsourcing in Discovery Chemistry Strategy Selection Success
Hansjoerg Lehmann, Novartis Pharma AG, speaking at Discovery Chemistry Congress 2012.

Thinking Small so as to Gain the Bigger Picture: Progress in High Throughput Bioprocess Development
Professor Nigel Titchener-Hooker, University College London, speaking at Bioprocessing, Biologics and Biotherapeutics Congress 2011.

Discovery Chemistry Outsourcing: Optimising the Process
Luigi LaVecchia, Director, Global Discovery Chemistry, Novartis speaking at Pharma Outsourcing Congress 2011

Chemical Synthesis and Rapid Scale-Up in Continuous Flow Reactors
Paul Watts, Senior Lecturer, University of Hull, speaking at Advances in Synthetic Chemistry

Scaling Out an SNAr Reaction in Microwave Flow Reactors
Jonathan Moseley, Associate Principal Scientist, AstraZeneca, speaking at Advances in Synthetic Chemistry

Heterogeneous Catalysis under Power Ultrasound and Microwaves
Giancarlo Cravotto, Professor, University of Torino, speaking at Advances in Synthetic Chemistry

Automated Sample Pretreatment of Environmental
Matrix elimination is a method of sample preparation that removes certain matrix species from a sample, typically by specifically binding matrix species to a solid phase. Interfering compounds can be removed before the analyte determination, thus improving the quality of results as well as lengthening the lifetime of consumables such as columns.

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