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January 2013
Scientific News
Charting Kidney Cancer Metabolism
Changes in cell metabolism are increasingly recognized as an important way tumors develop and progress, yet these changes are hard to measure and interpret. A new tool designed by MSK scientists allows users to identify metabolic changes in kidney cancer tumors that may one day be targets for therapy.
"Dark Side" of the Transcriptome
New approach to quantifying gene "read-outs" reveals important variations in protein synthesis and has implications for understanding neurodegenerative diseases.
Advancing Synthetic Biology
Living systems rely on a dizzying variety of chemical reactions essential to development and survival. Most of these involve a specialized class of protein molecules — the enzymes.
Structure of Brain Plaques in Huntington's
Researchers at the University of Pittsburgh School of Medicine have shown that the core of the protein clumps found in the brains of people with Huntington's disease have a distinctive structure, a finding that could shed light on the molecular mechanisms underlying the neurodegenerative disorder.
Visualizing a Cancer Drug Target at Atomic Resolution
Using cryo-electron microscopy, researchers were able to view, in atomic detail, the binding of a potential small molecule drug to a key protein in cancer cells.
Pumpjack" Mechanism for Splitting and Copying DNA
High-resolution structural details of cells' DNA-replicating proteins offer new insight into how these molecular machines function
The Power of Three
Overlooked portion of cell “death receptor” critical in some cancers, autoimmune diseases.
Biomarker for Recurring HPV-Linked Oropharyngeal Cancers
A look-back analysis of HPV infection antibodies in patients treated for oropharyngeal (mouth and throat) cancers linked to HPV infection suggests at least one of the antibodies could be useful in identifying those at risk for a recurrence of the cancer, say scientists at the Johns Hopkins University.
Light Signals from Living Cells
Fluorescent protein markers delivered under high pressure.
Cellular 'Relief Valve'
A team led by scientists at The Scripps Research Institute (TSRI) has solved a long-standing mystery in cell biology by showing essentially how a key “relief-valve” in cells does its job.
SLAS2013 – 2nd Annual Conference and Exhibition
12 Jan 2013 - 16 Jan 2013
Orlando, Florida, USA
SLAS2013 – 2nd Annual Conference and Exhibition
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15 Jan 2013 - 21 Feb 2013
Live-on-the-web
LC/MS Fundamentals and Applications
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Biomarkers Summit
16 Jan 2013 - 17 Jan 2013
London, UK
Biomarkers Summit
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20 Jan 2013 - 23 Jan 2013
Lillehammer, Norway
15th Nordic Conference in Mass Spectrometry
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PepTalk - The Protein Science Week
21 Jan 2013 - 25 Jan 2013
Palm Springs, California
PepTalk - The Protein Science Week
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22 Jan 2013 - 23 Jan 2013
Sheraton Hotel Brussels Belgium
Training ADME PK DM | Evaluation of ADMET Drug Properties in Drug Discovery and Development
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22 Jan 2013 - 23 Jan 2013
Boston, MA, USA
2nd Stratified Medicine Conference
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28 Jan 2013 - 30 Jan 2013
Washington DC
Phaciliate's Protein Therapeutics
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30 Jan 2013 - 01 Feb 2013
Pacific Grove, CA, USA
60th Annual Western Spectroscopy Association Conference
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