Corporate Banner
Satellite Banner
Proteomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Thermo Fisher Scientific and BrainMet Centre Collaborate on Dementia Research

Published: Thursday, March 04, 2010
Last Updated: Thursday, March 04, 2010
Bookmark and Share
The collaboration will advance dementia research by studying the effects of metals and metalloproteins in ageing and neurodegenerative diseases.

Thermo Fisher Scientific Inc. has announced that it is collaborating with the BrainMet (Bioimaging of Metals in Brain and Metallomics) Centre at Forschungszentrum, Julich, Germany to advance dementia research by studying the effects of metals and metalloproteins in ageing and in the origin of neurodegenerative diseases like Alzheimer’s and Parkinson’s diseases and Wilson’s syndrome.

To carry out the challenging research in the BrainMet laboratory, a Thermo Scientific XSERIES 2 inductively coupled plasma mass spectrometer (ICP-MS) was installed, combining third-generation collision cell and protective ion extraction technologies with an ergonomic, compact design.

Led by Dr. habil. Sabine Becker, the BrainMet Centre was officially opened in collaboration with Thermo Fisher by Juergen Srega, vice president global products, scientific instruments, Thermo Fisher Scientific in December 2009 to investigate new technologies for dementia research.

In most neurodegenerative diseases, abnormal accumulations of metals are observed in the brain, leading to the destruction of the neural network and subsequent cell death. Analysts at the BrainMet Centre are researching the quantitative distribution of essential and toxic metals in thin native tissue sections on the brain. When combining the studies on the bioimaging of metals to metallomics it is possible to explore the relationship between metal ions and metalloproteins in brain tissue and neurodegenerative diseases, such as Alzheimer’s disease.

The resulting data from these studies are successfully combined by BrainMet with neuro-scientific imaging procedures (MRI, PET, auto-radiography, histochemical and optical imaging techniques) to enable high-tech biomedical research.

Dr. habil. J. Sabine Becker, head of the Analytical BrainMet Centre, comments: “We are delighted to have entered into this exciting collaboration with Thermo Fisher. The state-of-the-art XSERIES 2 has been extremely efficient for quantitative bioimaging of metals of healthy and diseased samples of brain tissue and also for investigating the growth of brain tumors and strokes. Our ultimate goal is to advance dementia research and help the pharmaceutical industry introduce new therapies. The XSERIES 2 is very reliable and easy to use while providing the high signal to background ratio and excellent sensitivity that is required for our research.”


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,100+ scientific posters on ePosters
  • More than 4,500+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Thermo, Children’s Hospital Los Angeles Partner
Children’s Hospital Los Angeles (CHLA) and Thermo Fisher Scientific have agreed to develop a next-generation sequencing (NGS)-based panel designed specifically for pediatric cancer research. The assay would be CHLA’s first NGS panel designed to target biomarkers associated with childhood cancers.
Friday, February 19, 2016
Thermo Fisher Agrees to Buy Alfa Aesar for $403M
The company announced a definitive agreement to buy the research chemical manufacturer for $403 million.
Friday, June 26, 2015
Thermo Fisher Q3 Revenues up 31 Percent
Thermo Fisher announced that revenues grew 31% to $4.17 billion for the third quarter ended September 27, 2014.
Thursday, October 23, 2014
Thermo Completes Sale of Cole-Parmer to GTCR
Thermo Fisher Scientific Inc. announced that it has completed the sale of its Cole-Parmer customer channel business to private equity firm GTCR LLC for approximately $480 million in cash.
Wednesday, August 20, 2014
Thermo to Sell Cole-Parmer for $480M
Company has signed a definitive agreement to sell its Cole-Parmer channel business to private equity firm GTCR, LLC for $480 million in cash.
Monday, July 21, 2014
Biodesign Institute, Thermo Fisher Partner on $9M Radiation Test
Partnership enters a new, $9M phase of a project to produce a diagnostic test to rapidly measure an individual’s level of absorption of ionizing radiation.
Wednesday, June 04, 2014
Thermo, Nuclea Biotechnologies Collaborate to Develop Diabetes Markers
Companies pooling their expertise to develop novel multiplexed research methods for high-throughput quantification of native insulin and its therapeutic analogs.
Monday, June 02, 2014
Thermo Reports 22% Revenue Rise in Q1 2014
Results include the addition of Life Technologies as of February 4, 2014, and exclude the previously announced related divestitures as of March 22, 2014.
Wednesday, April 23, 2014
Thermo, Harvard Establish Center for Multiplexed Proteomics
Thermo Fisher Scientific Center for Multiplexed Proteomics at Harvard Medical School aims to expedite understanding of complex disease mechanisms.
Thursday, March 20, 2014
Thermo Reports 6% Q4 Revenue Growth
Thermo Fisher Scientific Inc. reported its financial results for the fourth quarter and full year ended December 31, 2013.
Friday, January 31, 2014
Thermo Fisher Scientific and the DTU Form Systems Biology Collaboration
Orbitrap Fusion Tribrid LC-MS technology to power new cellular signaling network research.
Monday, September 02, 2013
Thermo Scientific Forms Technology Alliance Partnership With University of Birmingham
Collaboration aimed at advancing LC-MS techniques in life science research.
Friday, March 29, 2013
Record Revenues for Thermo Fisher Scientific
Revenue for the quarter grew 6% to $3.26 billion in 2012, versus $3.09 billion in 2011.
Thursday, January 31, 2013
Thermo Scientific Forms Technology Alliance Partnership with Barnett Institute
Collaboration focuses on advancing LC-MS techniques for protein analysis.
Monday, January 28, 2013
Thermo Scientific Enters into a Long-Term Agreement with Fujirebio
Combination of Thermo Scientific B•R•A•H•M•S PCT assay and Lumipulse platforms to test patients suspected of having sepsis.
Thursday, November 22, 2012
Scientific News
Advancing Protein Visualization
Cryo-EM methods can determine structures of small proteins bound to potential drug candidates.
Alzheimer’s Protein Serves as Natural Antibiotic
Alzheimer's-associated amyloid plaques may be part of natural process to trap microbes, findings suggest new therapeutic strategies.
Structure of Essential Digestive Enzyme Uncovered
Using a powerful combination of techniques from biophysics to mathematics, researchers have revealed new insights into the mechanism of a liver enzyme that is critical for human health.
Getting a Better Look at How HIV Infects and Takes Over its Host Cells
A new approach, developed by a team of researchers led by The Rockefeller University and The Aaron Diamond AIDS Research Center (ADARC), offers an unprecedented view of how a virus infects and appropriates a host cell, step by step.
Untangling Disease-Related Protein Misfolding
Work advances understanding of genetic forms of thrombosis, emphysema, cirrhosis of the liver, neurodegenerative diseases and inflammation, among others.
Scientists Find Evidence That Cancer Can Arise Changes
Researchers at Rockefeller University have found a mutation that affects the proteins that package DNA without changing the DNA itself can cause a rare form of cancer.
US-India Collab Finds Molecular Signatures of Severe Malaria
Study may be a significant advancement in understanding the causes of severe malaria.
Triple-Negative Breast Cancer Target Is Found
Researchers at UC Berkeley discover a target that drives cancer metabolism in triple-negative breast cancer.
Crucial Reaction for Vision Revealed
Scientists have tracked the reaction of a protein responding to light, paving the way for a new understanding of life's essential reactions.
Cancer Can Arise from Histone Mutations
A mutation that affects the proteins that package DNA—without changing the DNA itself—can cause a rare form of cancer.
Scroll Up
Scroll Down
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,100+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,500+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!