Corporate Banner
Satellite Banner
Proteomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Scientists Develop Artificial Biominerals

Published: Thursday, September 08, 2011
Last Updated: Thursday, September 08, 2011
Bookmark and Share
Scientists have created synthetic crystals whose structures and properties mimic of naturally occurring biominerals.

Scientists have successfully created synthetic crystals whose structures and properties mimic those of naturally occurring biominerals such as seashells.

The findings, published in the journal Nature Materials, could be an important step in the development of high-performance materials, which could be manufactured under environmentally-friendly conditions.

Biological minerals or ‘biominerals’ occur widely throughout nature in structures such as bones, teeth and seashells and frequently show remarkable shapes and properties compared with their synthetic counterparts.

A key feature of biominerals is that they are composite materials, made from an inorganic mineral such as calcium carbonate which contains a small amount of organic material, usually a protein.

The resulting structures are incredibly hard and their mechanical properties can rival those of man-made materials such as ceramics, which are typically manufactured under high temperatures and pressures, giving less opportunity for control over the material properties.

Scientists are interested in understanding how biology is able to perform such precision engineering in water at ambient temperatures so they can apply this principle to the design and production of synthetic materials that are much greener than existing ones.

Now a team led by Professor Fiona Meldrum, from the University of Leeds School of Chemistry, has succeeded in creating artificial biominerals that exhibit similar properties to biominerals such as sea urchin spines.

They did this by growing calcite crystals in the presence of synthetic polymer nanoparticles which act as artificial proteins. These nanoparticles are incorporated into the architecture of the crystal as it grows to create a composite material.

The researchers also tested the mechanical properties of the composite material using a nanoindenter, a small chisel-like tool that can prod a material and record its response to a force.

Professor Meldrum said: “This method of creating synthetic biominerals gives us a unique insight into the structure of these incredible materials and the way the organic molecules are incorporated into the crystal structure at a microscopic level. We can then relate this microscopic structure to the mechanical properties of the material.

“What we found is that the artificial biomineral we have created is actually much harder than the pure calcite mineral because it is a composite material - where you add something soft to a hard substance to create something even harder than either of the constituent parts.”

Co-author Professor Stephen Eichhorn, who has just moved to the University of Exeter from the University of Manchester, said: "Biological examples of calcium carbonate-based structures have a higher hardness than pure mineral without proteins present. It is remarkable that we have been able to achieve the same result using a synthetic 'pseudo' protein."

"When I began researching the mechanical properties of seashells at Manchester my first PhD student and I literally collected them with a bucket and spade on the beach. I didn't imagine that we would get to the stage of being able to measure similar properties for materials made in the lab."

The researchers will now try to replicate their technique using different minerals. The research was a collaboration between the Universities of Leeds, Sheffield, Manchester and York, and the Israel Institute of Technology. It was funded by the Engineering and Physical Sciences Research Council.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,000+ scientific posters on ePosters
  • More than 4,500+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Innovative Way of Developing New Drugs
Scientists have developed an innovative way of using one of the biggest problems facing health services—antibiotic resistance—to develop drugs to combat some of the most intractable diseases.
Wednesday, December 16, 2015
Controlling the ‘Social Life’ of Proteins Aims to Transform Drug Discovery
A new £3.4 million programme will develop new tools to understand which interactions between proteins in the human body are relevant to disease.
Wednesday, December 16, 2015
Study Finds Non-Genetic Cancer Mechanism
Cancer can be caused solely by protein imbalances within cells, a study of ovarian cancer has found.
Tuesday, July 28, 2015
Protein Responsible for Blood Vessel Growth in Tumours Discovered
Scientists have discovered a new protein which triggers the growth of blood vessels in breast cancer tumours which have spread to the brain, a common location which breast cancer can spread to.
Wednesday, July 01, 2015
Scientific News
New Autism Blood Biomarker Identified
Researchers at UT Southwestern Medical Center have identified a blood biomarker that may aid in earlier diagnosis of children with autism spectrum disorder, or ASD.
FNIH Launches Project to Evaluate Biomarkers in Cancer Patients
Company has announced that it has launched a new project to evaluate the effectiveness of liquid biopsies as biomarkers in colorectal cancer patients.
HIV Particles Used to Trap Intact Mammalian Protein Complexes
Belgian scientists from VIB and UGent developed Virotrap, a viral particle sorting approach for purifying protein complexes under native conditions.
Potential “Good Fat” Biomarker
New method to measure the activity of energy consuming brown fat cells could ease the testing weight loss drugs.
Computational Model Finds New Protein-Protein Interactions
Researchers at University of Pittsburgh have discovered 500 new protein-protein interactions (PPIs) associated with genes linked to schizophrenia.
New Insights into Gene Regulation
Researchers have solved the three-dimensional structure of a gene repression complex that is known to play a role in cancer.
Controlling RNA in Living Cells
Modular, programmable proteins can be used to track or manipulate gene expression.
Soy Shows Promise as Natural Anti-Microbial Agent
Soy isoflavones and peptides may inhibit the growth of microbial pathogens that cause food-borne illnesses, according to a new study from University of Guelph researchers.
Potential Target for Revolutionary Antibiotics
An international team of including the Lomonosov Moscow State University researchers discovered which enzyme enables Escherichia coli bacterium (E. coli) to breathe.
DNA Barcodes Gone Wild
A team of researchers at University of Toronto’s Donnelly Centre and Sinai Health System’s Lunenfeld-Tanenbaum Research Institute (LTRI) has developed a new technology that can stitch together DNA barcodes inside a cell to simultaneously search amongst millions of protein pairs for protein interactions.
Scroll Up
Scroll Down
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,000+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,500+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!