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The Next Phase of Life-Sciences Spaceflight Research: Harnessing the Power of Functional Genomics

Published: Monday, April 02, 2012
Last Updated: Monday, April 02, 2012
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This article discusses potential applications of RNAi and GFP in spaceflight studies and the ramifications of these experiments for the future of space life-sciences research.

Spaceflight appears to induce metabolic changes in all species yet studied, many of which are suggested to have detrimental consequences for crew health and performance. These (mal)adaptations represent a major obstacle preventing the worlds’ space agencies from safely achieving their common goal of sending humans on long duration deep-space exploratory missions, and ultimately the human habitation of other planetary bodies. To overcome this obstacle we must first understand the molecular mechanisms regulating spaceflight-induced alterations and, second, utilize this knowledge to effectively target efforts to develop therapeutic strategies.

This article is published online in Communicative and Integrative Biology and is free to access.


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