Corporate Banner
Satellite Banner
Proteomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

ASU Partners With Life Tech on Development of Technologies to Rapidly Assess Radiation Dose

Published: Tuesday, January 22, 2013
Last Updated: Tuesday, January 22, 2013
Bookmark and Share
Arizona State University enters next phase of a multi-million-dollar, multi-institutional research project to develop a medical device to rapidly assess an individual’s exposure to radiation in the event of a nuclear incident.

The project enters a $9.33 million contract option as part of a five-year, $35.44 million project funded by the Biomedical Advanced Research and Development Authority (BARDA) within the Office of the Assistant Secretary for Preparedness and Response, US Department of Health and Human Services.  This phase will focus on prototype development of a gene-expression based system for individuals exposed to abnormal levels of radiation.

“We are pleased that Life Technologies is joining our team as a commercial partner,” said Lee Cheatham, Ph.D., deputy director of ASU’s Biodesign Institute® and lead investigator of the project. “We have completed initial scientific feasibility and now must develop a working device.  Life Technologies’ experience in delivering FDA-cleared assay systems to the marketplace is a great fit for this project.  Their strong product focus will ensure that we develop for BARDA an effective and easy-to-use system.”

“In the event of a nuclear emergency, potentially thousands of people would need to be screened per day,” said Ronnie Andrews, president of medical sciences at Life Technologies. “We are very proud of the robustness of our instruments that they would be selected for this type of application.”

The partnership is designed to develop genetic assays that would be run on several Life Technologies real-time PCR instruments including the Applied Biosystems® 7500 Fast Dx and the QuantStudio™ Dx[1]. All of these instruments perform a reaction called real-time PCR (polymerase chain reaction), a method of rapidly producing DNA from a small starting amount, detecting genetic matches if present and reporting the results.

Since the project was launched in 2010, ASU has led the research activities, demonstrating that the science of gene expression is a viable approach to directly measure radiation exposure.  Of the eleven project teams launched in 2010, the ASU team is one of six continuing development.

Developing the system required the identification and validation of biomarker signatures to provide an accurate indication for the level of absorbed radiation.  Dr. Joshua LaBaer, director of the institute’s Virginia G. Piper Center for Personalized Diagnostics is leading the biomarker effort.  Sally Amundson, Ph.D., Columbia University Medical Center in New York City, is providing extensive experience in the identification of radiation responsive genes and biodosimetry measurements.  Researchers from Translational Genomics Institute (TGen) in Phoenix, HTG Molecular in Tucson, and the University of Arizona have also contributed to the early phases of the project.

The ASU effort is part of BARDA’s congressionally mandated program to develop medical countermeasures against chemical, biological, radiological and nuclear threats, and against pandemic influenza and emerging infectious disease outbreaks and other natural and intentional threats to public health.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,000+ scientific posters on ePosters
  • More than 4,500+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
HIV Particles Used to Trap Intact Mammalian Protein Complexes
Belgian scientists from VIB and UGent developed Virotrap, a viral particle sorting approach for purifying protein complexes under native conditions.
Potential “Good Fat” Biomarker
New method to measure the activity of energy consuming brown fat cells could ease the testing weight loss drugs.
Computational Model Finds New Protein-Protein Interactions
Researchers at University of Pittsburgh have discovered 500 new protein-protein interactions (PPIs) associated with genes linked to schizophrenia.
New Insights into Gene Regulation
Researchers have solved the three-dimensional structure of a gene repression complex that is known to play a role in cancer.
Controlling RNA in Living Cells
Modular, programmable proteins can be used to track or manipulate gene expression.
Soy Shows Promise as Natural Anti-Microbial Agent
Soy isoflavones and peptides may inhibit the growth of microbial pathogens that cause food-borne illnesses, according to a new study from University of Guelph researchers.
Potential Target for Revolutionary Antibiotics
An international team of including the Lomonosov Moscow State University researchers discovered which enzyme enables Escherichia coli bacterium (E. coli) to breathe.
DNA Barcodes Gone Wild
A team of researchers at University of Toronto’s Donnelly Centre and Sinai Health System’s Lunenfeld-Tanenbaum Research Institute (LTRI) has developed a new technology that can stitch together DNA barcodes inside a cell to simultaneously search amongst millions of protein pairs for protein interactions.
Biomarkers for Profiling Prostate Cancer Patients
Exiqon A/S has announced the publication of validation of prognostic microRNA biomarkers for the aggressiveness of prostate cancer in independent cohorts.
Grant to Fund Million Peaks Project
The European Research Council (ERC) has awarded a prestigious Advanced Grant to Prof. Peter Schoenmakers, Prof. Albert Polman and Prof. Huib Bakker, all three of whom work at the University of Amsterdam (UvA).
Scroll Up
Scroll Down
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,000+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,500+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!