Corporate Banner
Satellite Banner
Proteomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Dezima In-Licenses CETP Inhibitor Program from MTPC

Published: Thursday, April 25, 2013
Last Updated: Thursday, April 25, 2013
Bookmark and Share
World-renowned dyslipidemia experts join Dezima’s Scientific Advisory Board.

Dezima Pharma (‘Dezima’) has announced the in-licensing of a cholesteryl ester transfer protein (CETP) inhibitor DEZ-001 (formerly TA-8995) from Mitsubishi Tanabe Pharma Corporation (MTPC). Terms of the deal were not disclosed.

DEZ-001 has completed single and multiple ascending dose studies showing an unprecedented effect on high density lipoprotein (HDL) and low density lipoprotein (LDL) levels in healthy volunteers with a very favourable side-effect profile.

The company plans to support clinical development of DEZ-001 to Phase 3 clinical trials.

Professor John Kastelein, founder of Dezima, co-founder of UniQure and advisor to Forbion Capital Partners, identified DEZ-001 as a potentially best-in-class, potent and safe CETP inhibitor.

At the same time, Dezima also reported the strengthening of its Scientific Advisory Board (SAB) with the addition of two world-leading experts in the dyslipidemia space: Dr Philip Barter, President of the International Atherosclerosis Society and Conjoint Professor at The University of New South Wales, Sydney, Australia, and Dr Bryan Brewer, Director at Washington Cardiovascular Associates and Senior Research Consultant of Lipoprotein and Atherosclerosis Research at the Medstar Research Institute, Washington DC, USA.

Professor Kastelein, Dezima’s CSO and Chairman of its SAB, commented: “CETP inhibitors hold enormous potential to further normalize lipid levels in millions of dyslipidemic patients worldwide. This product was a compelling in-licensing prospect because of its promising early clinical efficacy and safety profile. By applying a smart development program, DEZ-001 could potentially enter the market at a time similar to competing CETP inhibitors.”

Sander van Deventer, Dezima’s interim-CEO and General Partner at Forbion Capital Partners, who seed-financed Dezima together with BioGeneration Ventures, added: “The dyslipidemia space represents an attractive investment opportunity due to the continued high unmet medical need and the introduction of several next-generation therapeutic approaches. The addition of these two renowned experts to Dezima’s SAB will support the company in advancing DEZ-001, and in helping to identify additional earlier-stage dyslipidemia assets in order to develop a range of promising therapies in the CVD field.”


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,500+ scientific posters on ePosters
  • More than 5,000+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Dezima Initiates Phase 2b TULIP Study on CETP Inhibitor Program DEZ-001
TULIP study will investigate the effects of different doses of DEZ-001 on CVD biomarkers.
Friday, August 30, 2013
Scientific News
Mass Spec Technology Drives Innovation Across the Biopharma Workflow
With greater resolving power, analytical speed, and accuracy, new mass spectrometry technology and techniques are infiltrating the biopharmaceuticals workflow.
One Step Closer to Precision Medicine for Chronic Lung Disease Sufferers
A study led by University of North Carolina at Chapel Hill, and National Jewish Health, has provided evidence of links between SNPs and known COPD blood protein biomarkers.
New Imaging Technique in Alzheimer’s Disease
Study confirms new imaging technique corresponds a higher degree of actual brain changes.
Ancient Eggshell Protein Breaks Through DNA Time Barrier
Fossil proteins from a 3.8million year-old eggshell have been identifed, suggests proteins could give insight into evolutionary tree.
New Weapon Against Hard-to-Treat Bacterial Infections
Using peptides, researchers have been able to prevent drug-resistance bacteria from forming abscesses.
Designing Drugs with a Whole New Toolbox
Researchers develop methods to design small, targeted proteins with shapes not found in nature.
Protein Studies Discover Molecular Secrets
Two protein studies have mapped proteins that reveal the secrets to recycling carbon and healing cells.
Tapping Evolution to Improve Biotech Products
Researchers show how 'ancestral sequence reconstruction' can be used to guide engineering of a blood clotting protein.
Death-or-Repair Switch Protein Identified
Researchers have identified a protein that plays a key role in the decision process of cell damage repair or cellular suicide.
Gene Deletion Reveals Cell Secrets
Researchers have deleted 174 genes in yeast to analyse the effect of individual gene deletion.
Scroll Up
Scroll Down
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,000+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!