Corporate Banner
Satellite Banner
Scientific Community
Become a Member | Sign in
Home>News>This Article

3 Steps to Safer and Simpler DNA Gel Electrophoresis

Published: Friday, July 05, 2013
Last Updated: Friday, July 05, 2013
Bookmark and Share
‘Safe’ Series of products from Cleaver Scientific.

Helping to make DNA electrophoresis procedures safer, more convenient and more economical are the fundamental principles behind the development of the ‘Safe’ Series of products from Cleaver Scientific (CSL).

Laboratories around the world will acknowledge that there are two main hazards with traditional DNA gel electrophoresis.

For example, the stain most commonly used is Ethidium Bromide which is a mutagen and carcinogen, whilst the illumination source most often used is Ultra Violet, which can cause eye and skin damage.

Furthermore, traditional DNA electrophoresis is usually performed without the researcher knowing much about what is happening on the gel unit until is stopped and checked.

This is essentially a ‘blind, stop and start’ process where the electrophoresis run is stopped at the time the researcher thinks that the samples have separated out enough.

The gel is then taken to another room for checking and photographing and if the samples have not run enough, the gel is taken back to the tank and the time consuming process is repeated. If the samples have run too far the situation is worse because an entire new gel must be cast and run.

The ‘Safe’ Series offers a safer and more user-friendly alternative to traditional methods as it eliminates the need for Ethidium Bromide and the need for ultra violet light, without compromising the results of electrophoresis procedures.

The ‘Safe’ Series comprises runSafe, a completely safe stain for DNA and runView, a gel electrophoresis system that utilizes safe blue light and finally runDoc, a bench top gel documentation system which sits above the gel tank and enables multiple real-time images of the process to be taken.

With runView and runSafe, the separation of the DNA bands can be viewed in real-time, allowing the researcher to have complete control of the time of the electrophoresis run to achieve exactly the separation required.

In summary, the runView, runSafe and runDoc system provides a safe, economic, convenient and easy-to-use integrated solution for DNA electrophoresis covering each stage of the process.

It enables casting, loading, running, staining, viewing and documentation of DNA and RNA gels in a completely safe environment which requires no additional equipment, space or dark room.

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Environmentally Friendly Agarose for Nucleic Acid Electrophoresis
Cleaver Scientific, specialists in gel electrophoresis has introduced a new range of high grade agarose for nucleic acid electrophoresis.
Wednesday, May 27, 2015
Scientific News
Measuring microRNAs in Blood to Speed Cancer Detection
A simple, ultrasensitive microRNA sensor holds promise for the design of new diagnostic strategies and, potentially, for the prognosis and treatment of pancreatic and other cancers.
Novel Proteins Linked to Huntington's Disease
University of Florida Health researchers have made a new discovery about Huntington's disease, showing that the gene that causes the fatal disorder makes an unexpected "cocktail" of mutant proteins that accumulate in the brain.
Enzyme Critical to Maintaining Telomere Length Discovered
New method expected to speed understanding of short telomere diseases and cancer.
New Method Identifies Up to Twice as Many Proteins and Peptides
An international team of researchers developed a method that identifies up to twice as many proteins and peptides in mass spectrometry data than conventional approaches.
Metabolic Profiles Distinguish Early Stage Ovarian Cancer with Unprecedented Accuracy
Studying blood serum compounds of different molecular weights has led scientists to a set of biomarkers that may enable development of a highly accurate screening test for early-stage ovarian cancer.
New Way to Force Stem Cells to Become Bone Cells
Potential therapies based on this discovery could help people heal bone injuries or set hardware, such as replacement knees and hips.
Long-Sought Protein Sensor for the ‘Sixth Sense’ Discovered
In a study led by scientists from The Scripps Research Institute (TSRI)the sensor protein for propioception has been identified.
How Viruses Commandeer Human Proteins
Researchers have produced the first image of an important human protein as it binds with ribonucleic acid (RNA), a discovery that could offer clues to how some viruses, including HIV, control expression of their genetic material.
Tracking How Herpes Simplex Virus Moves Through Cells
In a recent study, Derek Walsh, PhD, associate professor of Microbiology-Immunology, and his team showed how the herpes simplex virus (HSV) exploits microtubule plus-end tracking proteins to initiate transport and infection in human cells.
Essential Component of Antiviral Defense Identified
Infectious disease researchers at the University of Georgia have identified a signaling protein critical for host defense against influenza infection.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos