Corporate Banner
Satellite Banner
Proteomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

WHEATON® Offers a Turnkey Solution for CHO Cell Bioproduction

Published: Wednesday, August 07, 2013
Last Updated: Wednesday, August 07, 2013
Bookmark and Share
WHEATON® CELLine™ Bioreactor combined with an optimized CHO medium formulation by Irvine Scientific expedites small-scale antibody and protein production.

WHEATON® and Irvine Scientific have collaborated to introduce a high yield, small-scale solution for bioproduction. The solution consists of a WHEATON® CELLine™ bioreactor flask paired with Irvine Scientific’s BalanCD™ CHO Growth A animal component-free, chemically-defined medium.

Scientists may now quickly set up and perform small-scale antibody and protein production while decreasing the cost per milligram produced. This bundled product is available now from WHEATON® and its extensive distributor network.

Antibodies and proteins for research and therapeutic purposes are typically produced in a modified cloned cell. The most widely used cells for in vitro production methods are Chinese Hamster Ovary (CHO) cells due to their stable gene expression, rapid growth, high protein production rate, and rich background of published data.

The combination of a high-throughput bioreactor, an optimized medium formulation, and an easy to follow protocol for cultivating CHO cells, provides a highly productive development platform.

WHEATON® CELLine™ Bioreactors provide an ideal growth environment for high-density cell cultures.

Cells are separated from the bulk growth medium by a dialysis membrane that regulates the flow of nutrients and waste products to and from the cell chamber.

The lower side of the cell chamber is made of a gas permeable membrane allowing continuous exchange of oxygen and carbon dioxide promoting high-density cultures.

CELLine™ bioreactor increases overall yields, and reduces use of consumables and production costs.

Irvine Scientific, a large-scale producer of advanced cell culture media, developed BalanCD™ CHO Growth A medium for optimum CHO cell growth and production.

This particular formulation, in combination with the CELLine™ bioreactor, yields antibody levels higher than conventional methods without the use of a mechanical shaker or agitation.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,200+ scientific posters on ePosters
  • More than 4,600+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

WHEATON® Announces Acquisition of CELLine™
WHEATON has acquired the CELLine bioreactor flask line for antibody and protein production from Wilson Wolf Manufacturing Corporation.
Tuesday, July 10, 2012
Scientific News
ASMS 2016: Targeting Mass Spectrometry Tools for the Masses
The expanding application range of MS in life sciences, food, energy, and health sciences research was highlighted at this year's ASMS meeting in San Antonio, Texas.
Proteins in Blood of Heart Disease Patients May Predict Adverse Events
Nine-protein test shown superior to conventional assessments of risk.
Self-Assembling Protein Shell for Drug Delivery
Made-to-order nano-cages open possibilities of shipping cargo into living cells or fashioning small chemical reactors.
Molecular Map Provides Clues To Zinc-Related Diseases
Mapping the molecular structure where medicine goes to work is a crucial step toward drug discovery against deadly diseases.
Nanoprobe Enables Measurement of Protein Dynamics in Living Cells
Mass. General and Harvard researchers use device to measure how anesthetic affects levels of Alzheimer's-associated proteins.
Diagnosing Systemic Infections Quickly, Reliably
Team develop rapid and specific diagnostic assay that could help physicians decide within an hour whether a patient has a systemic infection and should be hospitalized for aggressive intervention therapy.
What Makes a Good Scientist?
It’s the journey, not just the destination that counts as a scientist when conducting research.
A New Tool Brings Personalized Medicine Closer
Scientists from EPFL and ETHZ have developed a powerful tool for exploring and determining the inherent biological differences between individuals, which overcomes a major hurdle for personalized medicine.
Blood Test That Detects Early Alzheimer’s Disease
A research team, led by Dr. Robert Nagele from Rowan University School of Osteopathic Medicine and Durin Technologies, Inc., has announced the development of a blood test that leverages the body’s immune response system to detect an early stage of Alzheimer’s disease – referred to as the mild cognitive impairment (MCI) stage – with unparalleled accuracy.
‘Missing Tooth’ Hydrogels Handle Hard-to-Deliver Drugs
Rice University’s custom hydrogel traps water-avoiding molecules for slow delivery.
Scroll Up
Scroll Down
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,200+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,600+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!