Corporate Banner
Satellite Banner
Scientific Community
Become a Member | Sign in
Home>News>This Article

Ubiquigent Announces £0.5M Funding

Published: Thursday, September 19, 2013
Last Updated: Thursday, September 19, 2013
Bookmark and Share
Company also strengthens board of directors with key appointment.

Ubiquigent Limited has announced that it has received £0.5 million in funding from IP Group plc and the Scottish Investment Bank, the investment arm of Scottish Enterprise.

The investment will be used to accelerate the development and commercialization of these drug discovery platforms.

Ubiquigent has also announced an appointment to strengthen its board of directors. Joining the board as a Non-Executive Director, effective immediately, is Dr Mark Treherne.

Mark has been active in the pharmaceutical industry for over 25 years. In this time, he has been involved in starting and raising over £140 million for a number of early-stage biotechnology companies.

Amongst these, Mark was a co-founder and Chief Executive of Cambridge Drug Discovery, which was acquired by BioFocus plc. Mark has served on the boards of over 14 private and public biopharmaceutical companies in both executive and non-executive roles.

Located at the University of Dundee and with direct access to the leading scientific expertise of the Medical Research Council Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU), Ubiquigent develops and provides a range of reagents, kits, assay development, drug lead compound profiling (including DUBprofiler for profiling deubiquitylase enzyme inhibitors) and other services.

These products and services support academic and pharmaceutical researchers to understand the role of protein ubiquitylation in regulating many aspects of cellular functions and the development and optimization of drug candidate compounds that target the system addressing a number of critical therapeutic areas.

Ubiquigent already has a significant pharmaceutical and biotechnology client list and has delivered on a number of major high-throughput screening (HTS) assay development and compound profiling projects.

Involving the modification of proteins through the attachment of the protein ubiquitin, or ubiquitin-like proteins (Ubls), ubiquitylation and related Ubl modifications are key to the control of cellular protein homeostasis as well as signalling, akin to the critical role played by phosphorylation (approximately 20% of compounds in drug development target phosphorylation enzymes), and holds similar potential for clinical utility. The ubiquitin system offers many new drug discovery target opportunities across multiple therapeutic areas including oncology, neurodegeneration, cardiovascular and metabolic disorders.

The Company’s Scientific Advisory Board (SAB) is chaired by Professor Sir Philip Cohen, FRS, a world leading expert on the role of protein modifications in cellular regulation and the translation of this knowledge towards the treatment of human disease.

Also sitting on Ubiquigent’s SAB and contributing deep subject expertise are Professor Dario Alessi FRS (Director of the MRC-PPU) and Professor Ron Hay FRS.

Commenting on the funding Professor Cohen said: “The potential for developing drugs targeted at the ubiquitin system is very significant. The funding for Ubiquigent will ensure that novel capabilities are developed to enable ubiquitin-system drug discovery thus facilitating the addressing of new therapeutic targets across a wide range of disease areas.”

Dr Mark Treherne said: “I look forward to working closely with the Ubiquigent team to support the company in the planning and execution of its strategy in this high growth potential field. I also welcome the opportunity to work again alongside Professor Cohen with whom I had a very productive commercial collaboration in the past.”

Dr Jason Brown, Managing Director of Ubiquigent Ltd, added “We would like to thank IP Group plc and Scottish Enterprise for supporting the Company at this stage of its development. I look forward to working closely with Mark Treherne and other members of the management and Scientific Advisory Boards to lead the business through the next phase and deliver new approaches that help realize the full potential of this key area of drug discovery.”

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Scientific News
A Cellular Symphony Responsible for Autoimmune Disease
Broad Institute researchers have used a novel approach to increase our understanding of the immune system as a whole.
Non-Disease Proteins Kill Brain Cells
Scientists at the forefront of cutting-edge research into neurodegenerative diseases such as Alzheimer’s and Parkinson’s have shown that the mere presence of protein aggregates may be as important as their form and identity in inducing cell death in brain tissue.
Closing the Loop on an HIV Escape Mechanism
Research team finds that protein motions regulate virus infectivity.
New Class of RNA Tumor Suppressors Identified
Two short, “housekeeping” RNA molecules block cancer growth by binding to an important cancer-associated protein called KRAS. More than a quarter of all human cancers are missing these RNAs.
Gut Microbes Signal to the Brain When They're Full
Don't have room for dessert? The bacteria in your gut may be telling you something.
Turning up the Tap on Microbes Leads to Better Protein Patenting
Mining millions of proteins could become faster and easier with a new technique that may also transform the enzyme-catalyst industry, according to University of California, Davis, researchers.
Exploring the Causes of Cancer
Queen's research to understand the regulation of a cell surface protein involved in cancer.
Measuring microRNAs in Blood to Speed Cancer Detection
A simple, ultrasensitive microRNA sensor holds promise for the design of new diagnostic strategies and, potentially, for the prognosis and treatment of pancreatic and other cancers.
Novel Proteins Linked to Huntington's Disease
University of Florida Health researchers have made a new discovery about Huntington's disease, showing that the gene that causes the fatal disorder makes an unexpected "cocktail" of mutant proteins that accumulate in the brain.
Enzyme Critical to Maintaining Telomere Length Discovered
New method expected to speed understanding of short telomere diseases and cancer.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos