Corporate Banner
Satellite Banner
Proteomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Malvern Announces Guest Presenter for March 18th Protein Characterization Webinar

Published: Thursday, March 06, 2014
Last Updated: Thursday, March 06, 2014
Bookmark and Share
Renowned protein scientist Prof. Dr. John F. Carpenter shows how combining DLS with Raman Spectroscopy delivers new insights in protein stability, aggregation and structure.

Malvern Instruments welcomes Prof. Dr. John F. Carpenter, from the University of Colorado Center for Pharmaceutical Biotechnology, as a guest presenter contributing to the company’s current series of webinars.

Professor Carpenter is a renowned expert in mechanisms for protein degradation and stabilization in pharmaceutical formulations. In his webinar on 18 March 2014 he will discuss how the combination of dynamic light scattering technology with Raman spectroscopy delivers new insights into the measurement and prediction of protein stability, aggregation and high order structure.

Webinar registration is free and is open to all as part of Malvern’s continuing program of information and education. For further details and to register, please visit www.malvern.com/dlsraman.

The non-invasive and non-destructive determination of numerous physicochemical properties of protein therapeutics and their aggregates is critical for developing formulation conditions that enhance product efficacy, stability and manufacturability.

To meet the analytical challenges in early stage development, where the amount of material is limited, tools that measure very small volumes are also highly desirable.

In his webinar presentation, Prof. Carpenter will describe the combination of two established analytical techniques, dynamic light scattering (DLS) and Raman spectroscopy.

Together they can be used to derive structural, thermodynamic and kinetic insights into the mechanisms of protein aggregation and the factors that influence protein stability.

He will present a number of examples using model systems and manufactured biopharmaceutical products to illustrate the synergies of the two techniques and the new insights afforded by the combined approach.

Looking forward to the webinar, Dr Lisa Newey-Keane, Biopharmaceutical Portfolio Manager for Malvern, said, “We are delighted that Prof. Carpenter has agreed to talk about the work that he has been doing and to describe the use of a combined DLS/Raman Spectroscopy approach to protein characterization. His expertise in protein systems, especially in biopharmaceutical formulations, will provide a highly informative backdrop to the combined application of these two techniques and the examples he plans to describe will put this into the context of solving real-world problems.”

Prof. Dr. John F. Carpenter is an expert in mechanisms for protein degradation and stabilization in pharmaceutical formulations, during bioprocessing and in delivery systems. He has published more than 200 peer-reviewed papers and is an inventor on 19 issued patents.

He is Editor for Reviews and Commentaries for Journal of Pharmaceutical Sciences and serves on the Editorial Advisory Boards for various pharmaceutical journals.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,900+ scientific posters on ePosters
  • More than 4,200+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Malvern Signs Exclusive Agreement with Affinity Biosensors
Agreement to distribute Affinity Biosensors’ Archimedes system extends Malvern Instruments’ biopharma solutions.
Tuesday, March 05, 2013
Malvern Specialist Discusses Light Scattering Techniques at BioProcess International Europe 2011
Dr Hanna Jankevics will present a poster at the 7th annual BioProcess International Europe conference in Nice (France).
Thursday, April 14, 2011
Malvern Specialist Tests Sensitivity Limits of Dynamic Light Scattering
Malvern’s Zetasizer Nano systems use light scattering techniques to measure the hydrodynamic size, zeta potential and molecular weight of proteins and nanoparticles.
Wednesday, October 06, 2010
Scientific News
Retractable Protein Nanoneedles
The ability to control the transfer of molecules through cellular membranes is an important function in synthetic biology; a new study from researchers at Harvard’s Wyss Institute for Biologically Inspired Engineering and Harvard Medical School (HMS) introduces a novel mechanical method for controlling release of molecules inside cells.
A Crystal Clear View of Biomolecules
Fundamental discovery triggers paradigm shift in crystallography.
Charting Kidney Cancer Metabolism
Changes in cell metabolism are increasingly recognized as an important way tumors develop and progress, yet these changes are hard to measure and interpret. A new tool designed by MSK scientists allows users to identify metabolic changes in kidney cancer tumors that may one day be targets for therapy.
"Dark Side" of the Transcriptome
New approach to quantifying gene "read-outs" reveals important variations in protein synthesis and has implications for understanding neurodegenerative diseases.
Advancing Synthetic Biology
Living systems rely on a dizzying variety of chemical reactions essential to development and survival. Most of these involve a specialized class of protein molecules — the enzymes.
Structure of Brain Plaques in Huntington's
Researchers at the University of Pittsburgh School of Medicine have shown that the core of the protein clumps found in the brains of people with Huntington's disease have a distinctive structure, a finding that could shed light on the molecular mechanisms underlying the neurodegenerative disorder.
Visualizing a Cancer Drug Target at Atomic Resolution
Using cryo-electron microscopy, researchers were able to view, in atomic detail, the binding of a potential small molecule drug to a key protein in cancer cells.
Pumpjack" Mechanism for Splitting and Copying DNA
High-resolution structural details of cells' DNA-replicating proteins offer new insight into how these molecular machines function
The Power of Three
Overlooked portion of cell “death receptor” critical in some cancers, autoimmune diseases.
Biomarker for Recurring HPV-Linked Oropharyngeal Cancers
A look-back analysis of HPV infection antibodies in patients treated for oropharyngeal (mouth and throat) cancers linked to HPV infection suggests at least one of the antibodies could be useful in identifying those at risk for a recurrence of the cancer, say scientists at the Johns Hopkins University.
Scroll Up
Scroll Down
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,200+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!