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Bio-Rad Announced the Capability of its MicroRotofor™

Published: Wednesday, July 12, 2006
Last Updated: Wednesday, July 12, 2006
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The instrument enables scientists to enrich low abundance proteins for biomarker discovery.

Bio-Rad Laboratories, Inc. has announced the capability of its MicroRotofor™ cell instrument to enrich low-abundance proteins for biomarker discovery.

Biomarker discovery requires the ability to dig deeper into the proteome to find proteins that are of relatively low-abundance.

The effective study of low-abundance proteins often requires a fractionation step to reduce sample complexity and improve the concentration of low-abundance proteins.

With the MicroRotofor cell, formerly undetectable proteins can be enriched to levels that allow analysis by 2-D gel electrophoresis/mass spectrometry (2-D/MS) and liquid chromatography/tandem mass spectrometry (LC-MS/MS), methods that are commonly used in proteomics for the separation and identification of proteins.

The MicroRotofor cell is applied upstream of both 2-D/MS and LC-MS/MS workflows.

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