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Rapid Detection of Somatic Mutations in Cancer Genes
Michael J. Powell et. al.,

Rapid higly sensitive detection of tumor gene mutations in DNA derived from FFPE or plasma samples can be achieved with QClamp PCR technology.

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Accurate Normalization of Grain Samples Using Pressure-Based Volume Measurement Technology
Bill Gigante, John Thomas Bradshaw, Tanya Knaide

A common challenge experienced by sample screening facilities is identifying individual sample quantity prior to DNA extraction. Accurately identifying sample quantity allows the user to pipette exact amounts of extraction buffer into each well.

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Specificity of highly potent miRNA inhibitors
Barbara Roberston, Andrew Dalby, Yuriy Fedorov, Jon Karpilow, Anastasia Khvorova, Devin Leake, Annaleen Vermeulen

Specificity of highly potent miRNA inhibitors

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Expression of Wnt5a in Urothelial Carcinoma as a Potential Prognostic Marker
Mark Saling 1, Jordan K. Duckett 1, Scott Jenkinson 2 and Ramiro Malgor 3

Our results support the previous studies that suggest Wnt5a plays a pathological role in urothelial carcinoma.

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DHPLC Technology as a High-throughput Detection of Mutations in a Durum Wheat TILLING Population
Colasuonno P.1, Incerti O. 1, Lozito M.L. 1, Sbalzarini M. 2, Zaccagna P. 2, Papadimitriou S. 2, Blanco A. 1, Gadaleta A. 1

This study is a beautiful example of DHPLC technology application and shows an alternative tool to current strategies of SNP detection based on genotyping array.

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IDENTIFICATION AND DIFERENTIATION OF Verticillium SPECIES WITH PCR MARKERS AND SEQUENCING OF ITS REGION
Taja Jesenicnik, Nataša Štajner, Jernej Jakše, Sebastijan Radišek and Branka Javornik

The genus Verticillium is a group of ascomycete fungi, including plant-pathogenic species capable of affecting the vasculature of many agricultural crops, and therefore causes major economic losses worldwide. In 2011, a new taxonomic classification of the genus was proposed, which is now referred to as Verticillium sensu stricto, comprising ten species: V. dahliae V. albo-atru, V. alfalfae, V. longisporum, V. nonalfalfae, V. tricorpus, V. zaregamsianum, V. nubilum, V. isaacii and V. klebahnii. <

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Automated detection and control of controlled substances
Joe Bradley, Ian Johns

Scitegrity, in conjunction with the Pistoia Alliance and a number of pharmaceutical companies, have developed Controlled Substances Squared to scan large chemical libraries (millions of compounds) and determine whether a compound is considered as controlled in a selected country.

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Population characterization of Brazilian isolates of Ceratocystis spp. using microsatellites
Edson Luiz Furtado, Ana Carolina Firmino,  Michael Mbenoun, Denise Nakada Nosaki, Ariska Van der Nest, Jolanda Roux, Irene Bernes, Mike Wingfield

The genus Ceratocystis includes several species of economically important plant pathogens and has a global distribution. In Brazil, species in the genus cause disease and death of hosts such as cacao, eucalypts and mango. This study aimed to characterize the population structure and diversity of isolates of Ceratocystis fimbriata sensu lato collected from diseased Eucalyptus species and to compare these to isolates from cacao, mango, teak, fig, rubber and atemoya.

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Geneious R8: A Powerful and Comprehensive Suite of Molecular Biology Tools

Christian Olsen, Kashef Qaadri, Richard Moir, Matt Kearse, Simon Buxton, Matthew Cheung, Hengjie Wang, Jonas Kuhn, Steven Stones-Havas, Chris Duran

Geneious R8: A powerful and comprehensive suite of molecular biology tools.

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Showing Results 51 - 60 of 252
Scientific News
Cellular Contamination Pathway for Heavy Elements Identified
Berkeley Lab scientists find that an iron-binding protein can transport actinides into cells.
Lemon Juice and Human Norovirus
Citric acid may prevent the highly contagious norovirus from infecting humans, scientists discovered from the German Cancer Research Center.
Signature of Microbiomes Linked to Schizophrenia
Studying microbiomes in throat may help identify causes and treatments of brain disorder.
Structural Discoveries Could Aid in Better Drug Design
Scientists have uncovered the structural details of how some proteins interact to turn two different signals into a single integrated output.
Protein Found to Play a Key Role in Blocking Pathogen Survival
Calprotectin fends off microbial invaders by limiting access to iron, an important nutrient.
Study Identifies the Off Switch for Biofilm Formation
New discovery could help prevent the formation of infectious bacterial films on hospital equipment.
How DNA ‘Proofreader’ Proteins Pick and Edit Their Reading Material
Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have discovered how two important proofreader proteins know where to look for errors during DNA replication and how they work together to signal the body’s repair mechanism.
Protein Found to Control Inflammatory Response
A new Northwestern Medicine study shows that a protein called POP1 prevents severe inflammation and, potentially, diseases caused by excessive inflammatory responses.
X-ray Laser Experiment Could Help in Designing Drugs for Brain Disorders
Scientists found that when two protein structures in the brain join up, they act as an amplifier for a slight increase in calcium concentration, triggering a gunshot-like release of neurotransmitters from one neuron to another.
Team Identifies Structure of Tumor-Suppressing Protein
An international group of researchers led by Carnegie Mellon University physicists Mathias Lösche and Frank Heinrich have established the structure of an important tumor suppressing protein, PTEN.
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