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Discrimination of Meat Species Using Raman Spectroscopy and PCA
Reyhan Selin Uysala, Tümay Temiza, Ismail Hakki Boyacia,b, Hasan Murat Veliogluc, Ugur Tamerd

Discrimination of meat species and meat products was performed with using Raman spectroscopy and principal component analysis (PCA).

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Accurate Determination of Moisture Content of Soft Contact Lenses by Near-Infrared (NIR) Spectroscopy
Dr. Hari Narayanan, Dr. Keith Freel

NIR spectroscopy was used to determine moisture content in soft contact lenses to and accuracy of 1%. Various sample presentation methods were used and the results were compared.

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Accurate Determination of Moisture Content of Soft Contact Lenses by Near-Infrared (NIR) Spectroscopy
Dr. Hari Narayanan, Dr. Keith Freel

NIR spectroscopy was used to determine moisture content in soft contact lenses to and accuracy of 1%. Various sample presentation methods were used and the results were compared.

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Investigation of Chemical Contaminants in Soils Following Superstorm Sandy
Amy C Mandigo*, Dana J DiScenza*, Alison R Keimowitz†, and Neil Fitzgerald*

Investigation of Chemical Contaminants in Soils Following Superstorm Sandy

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Rapid analysis of 3D tumour spheroids in soft agar and on ultra-low attachment plates using a laser scanning imaging system
Anne F Hammerstein, Diana Caracino, and Paul Wylie

The requirement for better in-vitro models that are compatible with high-throughput screening campaigns has led to the development of 3D cell cultures models, especially muliticellular spheroids, which retain many of the morphological and genetic traits of tumours.
Here we describe the formation of such spheroids by two methods: on ultra-low attachment plates and in semi-solid agarose. Both methods are compatible with 96- and 384-well microplate formats.

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Combining low and high volume liquid handling capabilities for ADME screening
Joby Jenkins, Kevin Moore, Stephen Fowler, Pascal Schenk

In this study we demonstrate the integration of two liquid handlers to extend the volume dispensing range creating low-volume assay-ready plates with high accuracy and precision. This was then successfully applied to a CYP inhibition assay.

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Does the increase of exosomal microRNAs reflect an activated immune system in melanoma?
Nina Koliha, Florian S. Dreyer , Jochen Dindorf , Andreas Bosio, Andreas S. Baur , and Stefan Wild

Cutaneous malignant melanoma is a form of skin cancer that accounts for 65% of skin cancer-related deaths. The incidence increases continuously, and while early detection leads to nearly 100% survival rates, the mortality raises to greater than 80% for patients with advanced disease.

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A New Approach to Increase Yields and Improve Functionality of Recombinant Proteins
Antti Vasala, BioSilta Oy, Oulu, Finland

The ability to express and extract fully functional proteins in sufficient quantities from bacterial cultures is a prerequisite for many projects in which recombinant proteins are required for structural studies, functional characterization, as assay components or for other applications. However, low yield, poor solubility and lack of functionality are often associated with, what should be, a routine procedure.

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Fingerprinting analytical strategy used for authentication of honey
Oana Romina DINCAa,b, Roxana Elena IONETEa*, Raluca POPESCUa, Radu TAMAIANa, Diana COSTINELa, Gabriel Lucian RADUb

The goal of the current study is mainly to establish potential origin markers, and not to build a model for prediction. This research provides a database for comparison of honey samples from Romania with other honey samples from the world. Data on d13C, d18O and d2H of honey measured by IRMS together with the stable isotopes (deuterium by SNIF-NMR and carbon 13 - IRMS) in ethanol from fermented honeys were reported.

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Showing Results 51 - 60 of 174
Scientific News
Peptide Mimics as a Drug Target for Ebola
University of Utah researchers create a tool to develop treatments for Ebola using Protein Technologies’s peptide synthesizer.
Misfolded Proteins Clump Together in a Surprising Place
Stowers researchers create new framework for protein aggregation under acute stress.
New Technique Yields Drug, Biomedical Test Results in One Minute
Slug flow microextraction makes it possible to quickly detect the presence of drugs or to monitor certain medical conditions using only a single drop of blood or urine.
New Clues For Early Colorectal Cancer Detection
Study identifies new biomarkers which could help detect colorectal cancer.
New 'Lab-on-a-Chip' Could Revolutionize Early Diagnosis of Cancer
Faster result times, reduced costs, minimal sample demands and better sensitivity of analysis.
First Pictures of BRCA2 Protein Show How it Works to Repair DNA
Researchers purified the protein and used electron microscopy to reveal its structure.
NanoString, Brigham and Women’s Hospital Collaborate
Research collaboration to accelerate translation of genomic discoveries into clinical diagnostics in oncology.
Protein that Causes FTD also Implicated in Alzheimer’s Disease
Low levels of the naturally occurring protein progranulin exacerbate cellular and cognitive dysfunction, while raising levels can prevent abnormalities in an Alzheimer model.
Protein ‘Map’ Could Lead to Potent New Cancer Drugs
Findings will help scientists to design drugs that could target NMT enzyme.
Blood Test May Help Determine Psychosis Risk
A study led by University of North Carolina at Chapel Hill researchers represents an important step forward in the accurate diagnosis of people who are experiencing the earliest stages of psychosis.
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