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  Application Notes

Automating ELISAs on Tecan’s Freedom EVO® using Optimiser™ technology

Tecan Group Ltd.
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Automating Protein Digestion for Reproducible Proteomics

Beckman Coulter Life Sciences
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Avoiding Housekeeping Protein Detection Saturation

Bio-Rad Laboratories
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BD Cytometric Bead Array Cell Signaling Flex Set System

BD Biosciences
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BRD4 Bromodomain 1 Inhibitor Screening Using a Homogeneous Proximity A

BioTek Instruments
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Charge and Interaction Analysis for Predicting Antibody Formulation St

Wyatt Technology Corporation
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Comparison of Performance: EnSpire Multimode Plate Reader and Corning®

PerkinElmer
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Data Independent Label-Free Quantification of Low Abundance Proteins

Waters Corporation
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Determining the Appropriate Film Exposure Time

Bio-Rad Laboratories
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Scientific News
Structure of Brain Plaques in Huntington's
Researchers at the University of Pittsburgh School of Medicine have shown that the core of the protein clumps found in the brains of people with Huntington's disease have a distinctive structure, a finding that could shed light on the molecular mechanisms underlying the neurodegenerative disorder.
Visualizing a Cancer Drug Target at Atomic Resolution
Using cryo-electron microscopy, researchers were able to view, in atomic detail, the binding of a potential small molecule drug to a key protein in cancer cells.
Pumpjack" Mechanism for Splitting and Copying DNA
High-resolution structural details of cells' DNA-replicating proteins offer new insight into how these molecular machines function
The Power of Three
Overlooked portion of cell “death receptor” critical in some cancers, autoimmune diseases.
Biomarker for Recurring HPV-Linked Oropharyngeal Cancers
A look-back analysis of HPV infection antibodies in patients treated for oropharyngeal (mouth and throat) cancers linked to HPV infection suggests at least one of the antibodies could be useful in identifying those at risk for a recurrence of the cancer, say scientists at the Johns Hopkins University.
Light Signals from Living Cells
Fluorescent protein markers delivered under high pressure.
Cellular 'Relief Valve'
A team led by scientists at The Scripps Research Institute (TSRI) has solved a long-standing mystery in cell biology by showing essentially how a key “relief-valve” in cells does its job.
Genomic Signature Shared by Five Types of Cancer
National Institutes of Health researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.
Protein Protects Against Flu in Mice
The engineered molecule doesn’t provoke inflammation and may hail a new class of antivirals.
Cat Stem Cell Therapy Gives Humans Hope
By the time Bob the cat came to the UC Davis veterinary hospital, he had used up most of his nine lives.
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